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XLRN

Acceleron

$47.34

0.58 (1.24%)

05:51
07/10/18
07/10
05:51
07/10/18
05:51

Acceleron price target raised to $62 from $57 at UBS

UBS analyst Carter Gould raised his price target for Acceleron Pharma to $62 citing the positive results from the Phase 3 Believe study of luspatercept in beta-thalassemia. While not a surprise after the positive Medalist data two weeks ago, a "clear clinical win" was important given a lack of quantitative details in either press release, Gould tells investors in a research note. He keeps a Buy rating on Acceleron.

XLRN Acceleron
$47.34

0.58 (1.24%)

06/28/18
PIPR
06/28/18
NO CHANGE
Target $55
PIPR
Overweight
Acceleron price target raised to $55 at Piper Jaffray after luspatercept data
Piper Jaffray analyst Edward Tenthoff raised his price target on Acceleron (XLRN) to $55 and kept his Overweight rating after the company's Phase 3 MEDALIST trial of luspatercept in myelodysplastic syndromes - MDS - met the primary and secondary endpoints. The analyst notes that the company, along with its partner Celgene (CELG) will now report full data at a medical conference this year and then file an NDA and MAA in the first half of next year. Tenthoff adds that today's results increase his confidence for luspatercept in lower-risk, front-line MDS.
06/29/18
GSCO
06/29/18
UPGRADE
Target $40
GSCO
Neutral
Acceleron upgraded to Neutral from Sell at Goldman Sachs
Goldman Sachs analyst Terence Flynn upgraded Acceleron Pharma (XLRN) to Neutral and raised his price target for the shares to $40 from $21. The stock in premarket trading is up 26.5%, or $9.02, to $43.00. The Luspatercept Phase 3 myelodysplastic syndromes trial achieved a "highly" statistically significant improvement on the primary endpoint - transfusion independence compared to placebo, Flynn tells investors in a research note following last night's announcement. Following the trial success, the analyst expects the focus to shift increasingly to the drug's commercial opportunity. He raised his probability of success for Luspatercept to 90% from 75% in myelodysplastic syndromes and beta-thal. While the beta-thal Phase 3 trial is still ongoing, the safety commentary in the MDS trial release was a positive, Flynn argues. The analyst keeps a Sell rating on Acceleron's Luspatercept partner Celgene (CELG) while boosting his price target for the shares to $82 from $81. Celgene still needs to deliver on a number of upcoming pipeline events, Flynn says.
06/29/18
JPMS
06/29/18
NO CHANGE
Target $54
JPMS
Overweight
Acceleron shares have 30%-35% upside on 'clean win,' says JPMorgan
In a research note partially titled "Gooooal! A Clean Win for MEDALIST Phase 3," JPMorgan analyst Eric Joseph raised his price target for Acceleron Pharma to $54 from $52. While details on specific endpoints were light, the top-line announcement notes highly significant outcomes on both primary and key secondary endpoint, Joseph writes. The analyst views the outcome as a "clean win" that and "materially de-risks" the path forward to approval for luspatercept. He sees 30%-35% upside to current levels for Acceleron shares on higher probability of success assumptions across Street models on myelodysplastic syndromes alone. Joseph keeps an Overweight rating on Acceleron. The stock in premarket trading is up 26.5% to $43.00.
07/10/18
PIPR
07/10/18
DOWNGRADE
Target $52
PIPR
Neutral
Acceleron downgraded to Neutral from Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff downgraded Acceleron Pharma (XLRN) to Neutral and lowered his price target for the shares to $52 from $55. Acceleron and partner Celgene (CELG) last night announced positive Phase III Believe results for luspatercept in transfusion dependent beta thalassemia, Tenthoff tells investors in a research note. The stock in premarket trading is up $6.10, or 13%, to $53.50. This is a nice second win for luspatercept, but Acceleron shares are not a buy at current valuation levels, the analyst contends. He believes luspatercept does not command the same market opportunity in beta thalassemia due to the expected approval of curative gene therapy by 2020. As such, Tenthoff lowered his penetration rates for luspatercept in beta thal to account for gene therapy competition. He says, however, that partner Celgene could acquire Acceleron, which presents a risk to his downgrade.

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BOX

Box

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ALDX

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