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ACHN

Achillion

$2.98

-0.015 (-0.50%)

06:06
07/10/18
07/10
06:06
07/10/18
06:06

Achillion begins dosing in phase 1 trial of ACH-5548

Achillion Pharmaceuticals announced that the Company had begun dosing healthy volunteer subjects in a first-in-human phase 1 trial of ACH-5548, an oral small-molecule complement factor D inhibitor. ACH-5548 is the third clinical compound discovered and developed by Achillion from its complement factor D platform. ACH-5548 is structurally designed to achieve significant improvements in potency and pharmacokinetic properties over first-generation ACH-4471.

ACHN Achillion
$2.98

-0.015 (-0.50%)

12/11/17
LEER
12/11/17
NO CHANGE
Target $5
LEER
Outperform
Achillion '4471 on its way toward meaningful remissions, says Leerink
After speaking with MEDACorp nephrologists and conducting an analysis of recent data on the first two patients with C3 glomerulopathy treated with Achillion's ACH-4471, Leerink analyst Joseph Schwartz has an "enhanced appreciation" of the early signal of decreased proteinuria and market opportunity for it in C3G. The analyst believes '4471 is converging on modified partial remissions, which the FDA has stated may be used as a primary endpoint in other orphan kidney diseases. Schwartz is looking forward to data updates in 2018 on higher doses, longer duration of therapy, and more patients. He reiterates an Outperform rating and $5 price target on the shares.
12/15/17
LEER
12/15/17
NO CHANGE
Target $5
LEER
Outperform
Achillion CMO departure not a sign of problems with pipeline, says Leerink
Leerink analyst Joseph Schwartz spoke with Achillion after news that CMO David Apelian delivered his resignation and the analyst believes his departure is not indicative of any problems with the company's pipeline programs. Schwartz, who continues to see current levels as an attractive entry point to buy shares ahead of more de-risking data next year in the C3G market, keeps an Outperform rating on Achillion.
02/08/18
RILY
02/08/18
INITIATION
Target $3.5
RILY
Neutral
Achillion initiated with a Neutral at B. Riley FBR
B. Riley FBR analyst Madhu Kumar started Achillion Pharmaceuticals with a Neutral rating and $3.50 price target.
05/21/18
LEHM
05/21/18
UPGRADE
Target $5
LEHM
Equal Weight
Achillion upgraded to Equal Weight from Underweight at Barclays
Barclays analyst Geoffrey Meacham upgraded Achillion Pharmaceuticals to Equal Weight with an unchanged price target of $5. The analyst sees minimal downside risk from current valuation levels.

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YEXT

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YEXT

Yext

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SLG

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HSBC

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ODT

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URI

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ORCL

Oracle

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$NSD

NASDAQ Market Internals

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XOM

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COF

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WFC

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