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ACHN

Achillion

$2.98

-0.015 (-0.50%)

06:06
07/10/18
07/10
06:06
07/10/18
06:06

Achillion begins dosing in phase 1 trial of ACH-5548

Achillion Pharmaceuticals announced that the Company had begun dosing healthy volunteer subjects in a first-in-human phase 1 trial of ACH-5548, an oral small-molecule complement factor D inhibitor. ACH-5548 is the third clinical compound discovered and developed by Achillion from its complement factor D platform. ACH-5548 is structurally designed to achieve significant improvements in potency and pharmacokinetic properties over first-generation ACH-4471.

ACHN Achillion
$2.98

-0.015 (-0.50%)

12/11/17
LEER
12/11/17
NO CHANGE
Target $5
LEER
Outperform
Achillion '4471 on its way toward meaningful remissions, says Leerink
After speaking with MEDACorp nephrologists and conducting an analysis of recent data on the first two patients with C3 glomerulopathy treated with Achillion's ACH-4471, Leerink analyst Joseph Schwartz has an "enhanced appreciation" of the early signal of decreased proteinuria and market opportunity for it in C3G. The analyst believes '4471 is converging on modified partial remissions, which the FDA has stated may be used as a primary endpoint in other orphan kidney diseases. Schwartz is looking forward to data updates in 2018 on higher doses, longer duration of therapy, and more patients. He reiterates an Outperform rating and $5 price target on the shares.
12/15/17
LEER
12/15/17
NO CHANGE
Target $5
LEER
Outperform
Achillion CMO departure not a sign of problems with pipeline, says Leerink
Leerink analyst Joseph Schwartz spoke with Achillion after news that CMO David Apelian delivered his resignation and the analyst believes his departure is not indicative of any problems with the company's pipeline programs. Schwartz, who continues to see current levels as an attractive entry point to buy shares ahead of more de-risking data next year in the C3G market, keeps an Outperform rating on Achillion.
02/08/18
RILY
02/08/18
INITIATION
Target $3.5
RILY
Neutral
Achillion initiated with a Neutral at B. Riley FBR
B. Riley FBR analyst Madhu Kumar started Achillion Pharmaceuticals with a Neutral rating and $3.50 price target.
05/21/18
LEHM
05/21/18
UPGRADE
Target $5
LEHM
Equal Weight
Achillion upgraded to Equal Weight from Underweight at Barclays
Barclays analyst Geoffrey Meacham upgraded Achillion Pharmaceuticals to Equal Weight with an unchanged price target of $5. The analyst sees minimal downside risk from current valuation levels.

TODAY'S FREE FLY STORIES

BHLB

Berkshire Hills Bancorp

$40.80

0.15 (0.37%)

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PG

Procter & Gamble

$79.71

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GWW

Grainger

$338.99

33.78 (11.07%)

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MS

Morgan Stanley

$50.54

1.34 (2.72%)

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ESTA

Establishment Labs

$0.00

(0.00%)

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CNST

Constellation Pharmaceuticals

$0.00

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CARB

Carbonite

$37.90

0.6 (1.61%)

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TLRY

Tilray

$0.00

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  • 19

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JBLU

JetBlue

$19.97

0.44 (2.25%)

, EADSY

Airbus

$0.00

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EADSY

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  • 24

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PTC

PTC

$98.51

-0.4 (-0.40%)

20:28
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Recommendations
PTC analyst commentary at MUFG »

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  • 18

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PM

Philip Morris

$82.16

-0.17 (-0.21%)

, UNP

Union Pacific

$141.26

2.96 (2.14%)

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Earnings
Notable companies reporting before tomorrow's open »

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UNP

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DHR

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PPG

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KEY

KeyCorp

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FITB

Fifth Third

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NUE

Nucor

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GPC

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ADS

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DPZ

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DOV

Dover

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FFKT

Farmers Capital Bank

$53.50

0.65 (1.23%)

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APC

Anadarko

$71.49

0.06 (0.08%)

20:13
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  • 01

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HES

Hess Corp.

$64.14

0.67 (1.06%)

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Hess Corp. analyst commentary at MUFG »

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  • 25

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NBL

Noble Energy

$34.34

-0.11 (-0.32%)

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Noble Energy analyst commentary at MUFG »

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  • 03

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NDLS

Noodles & Company

$11.80

-0.35 (-2.88%)

, IBM

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Hot Stocks
On The Fly: After Hours Movers »

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RUN

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GSBC

Great Southern Bancorp

$58.55

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Earnings
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OMAB

OMA Airports

$45.82

-0.48 (-1.04%)

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OPTN

Optinose

$26.97

0.36 (1.35%)

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T

AT&T

$31.73

-0.02 (-0.06%)

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DOJ: AT&T-Time Warner ruling ignored 'basic economics,' FT reports »

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  • 24

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  • 09

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SBGI

Sinclair Broadcast

$27.35

-0.65 (-2.32%)

, TRCO

Tribune Media

$34.09

0.79 (2.37%)

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FCC votes unanimously to adopt hearing order on Sinclair-Tribune deal »

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SBGI

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$27.35

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TRCO

Tribune Media

$34.09

0.79 (2.37%)

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  • 08

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  • 06

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RUN

Sunrun

$15.16

-0.02 (-0.13%)

, JKS

JinkoSolar

$13.70

-0.1 (-0.72%)

18:25
07/18/18
07/18
18:25
07/18/18
18:25
Downgrade
Sunrun, JinkoSolar, Canadian Solar, Vivint Solar rating change at Goldman Sachs »

Sunrun downgraded to…

RUN

Sunrun

$15.16

-0.02 (-0.13%)

JKS

JinkoSolar

$13.70

-0.1 (-0.72%)

CSIQ

Canadian Solar

$12.83

0.15 (1.18%)

VSLR

Vivint Solar

$5.20

(0.00%)

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  • 07

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  • 09

    Aug

SBGI

Sinclair Broadcast

$27.35

-0.65 (-2.32%)

, TRCO

Tribune Media

$34.09

0.79 (2.37%)

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Periodicals
Breaking Periodicals news story on Sinclair Broadcast, Tribune Media »

FCC votes unanimously to…

SBGI

Sinclair Broadcast

$27.35

-0.65 (-2.32%)

TRCO

Tribune Media

$34.09

0.79 (2.37%)

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  • 08

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  • 06

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RUN

Sunrun

$15.16

-0.02 (-0.13%)

18:13
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Sunrun rating change at Goldman Sachs »

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  • 09

    Aug

UNH

UnitedHealth

$255.43

5.11 (2.04%)

, THC

Tenet

$34.57

-0.37 (-1.06%)

18:09
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18:09
Periodicals
UnitedHealth among suitors eyeing Tenet's Conifer unit, WSJ reports »

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UNH

UnitedHealth

$255.43

5.11 (2.04%)

THC

Tenet

$34.57

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  • 07

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