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AGN

Allergan

$175.85

0.21 (0.12%)

08:03
07/19/18
07/19
08:03
07/19/18
08:03

Allergan and Molecular Partners report 'positive' Phase 3 results for Abicipar

Allergan and Molecular Partners, a clinical-stage biopharmaceutical company developing a new class of drugs known as DARPin therapies, announced the release of two positive clinical trials, SEQUOIA and CEDAR for abicipar, demonstrating that both the 8-week and 12-week treatment regimens met the pre-specified primary endpoint of non-inferiority to ranibizumab. SEQUOIA and CEDAR are identical global phase 3 studies designed to assess the efficacy and safety of abicipar compared with ranibizumab in treatment-naive patients with neovascular age-related macular degeneration, or AMD. The primary endpoint measured the proportion of treated patients with stable vision at week 52. In both studies abicipar demonstrated similar efficacy after 6 or 8 injections, compared to 13 ranibizumab injections in the first year of this study. The overall adverse events were similar among the three treatment arms. SEQUOIA and CEDAR clinical trials continue on a masked basis for a second year. The filing for abicipar is planned for 1H19. Allergan will be requesting a meeting with the FDA to discuss the BLA submission.

  • 26

    Jul

AGN Allergan
$175.85

0.21 (0.12%)

07/12/18
CANT
07/12/18
INITIATION
Target $59
CANT
Overweight
Cantor puts $59 price target on 'undervalued' NASH play Galmed
Cantor Fitzgerald analyst Elemer Piros last night initiated coverage of Galmed Pharmaceuticals (GLMD) with an Overweight rating and $59 price target. The stock closed yesterday down 45c to $10.55. The company is developing Aramchol, a novel, once-daily, oral therapy to treat liver diseases using fattyacid/bile-acid conjugates, Piros tells investors in a research note. The analyst believes that by Q4 of 2019, only three meaningful non-alcoholic steatohepatitis pivotal programs will be in development: Allergan's (AGN) cenicriviroc, Madrigal Pharmaceuticals' (MDGL) MGL-3196, and Galmed's Aramchol. Of the three drugs, Galmed's has the highest likelihood of achieving improvement on NASH resolution without worsening of fibrosis, and improvement in fibrosis score without worsening of NASH, Piros argues. He believes Galmed is undervalued relative to peers in the NASH space.
07/09/18
MZHO
07/09/18
NO CHANGE
Target $194
MZHO
Neutral
Allergan price target raised to $194 from $176 at Mizuho
Mizuho analyst Irina Koffler raised her price target for Allergan to $194 after extending her model to 2025 to "assess the beneficial impact" of the company's pipeline. Her new price target reflects a long-term outlook but the analyst reiterates a Neutral rating on Allergan.
06/27/18
MAXM
06/27/18
INITIATION
Target $6
MAXM
Buy
VistaGen Therapeutics initiated with a Buy at Maxim
As reported earlier, Maxim analyst Caroline Palomeque initiated VistaGen Therapeutics (VTGN) with a Buy rating and a price target of $6 based on its lead drug candidate, AV-101, an oral antidepressant targeting modulation of the NMDA receptor which is an emerging new class of antidepressants. The analyst notes that while Johnson & Johnson (JNJ) and Allergan (AGN) have first mover advantage in the NMDA class, their respective intranasal and IV in-office administration differentiates AV-101 as an oral at-home alternative. Palomeque notes the company's is progressing with its clinical development, as AV-101 undergoes phase 2 studies in treatment resistant major depressive disorder and adjunctive therapy in frontline failed patients, with data expected in the second half of this year and first half of 2019 respectively.
06/13/18
WELS
06/13/18
NO CHANGE
Target $240
WELS
Outperform
Wells Fargo encouraged by data for Allergan's glaucoma treatment
Wells Fargo analyst David Maris said he was encouraged by the positive topline results reported by Allergan from the first of two Phase 3 studies of its glaucoma treatment Bimatoprost SR, which he believes will eventually strengthen the company's commercial glaucoma franchise. He projects Bimatoprost SR to enter the market in 2020 and grow to sales of $280M in 2022. Maris keeps an Outperform rating on Allergan shares.

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UBER

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USEG

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AAPL

Apple

$179.03

-0.64 (-0.36%)

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SPCB

SuperCom

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USEG

U.S. Energy

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MYOV

Myovant Sciences

$12.39

-0.465 (-3.62%)

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MYOV

Myovant Sciences

$12.39

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NVS

Novartis

$87.49

3.03 (3.59%)

, QGEN

Qiagen

$38.22

-0.255 (-0.66%)

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NVS

Novartis

$87.49

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QGEN

Qiagen

$38.22

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AVH

Avianca

$3.96

0.91 (29.84%)

16:56
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ANAC suspends flights, operations of Avianca Brasil, Reuters reports »

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AAPL

Apple

$179.03

-0.64 (-0.36%)

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SHSP

SharpSpring

$16.37

-0.24 (-1.44%)

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CREG

China Recycling Energy

$0.48

0.005 (1.05%)

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FENC

Fennec

$3.88

(0.00%)

16:36
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Fennec management to meet with Wedbush »

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TD

Toronto-Dominion

$56.66

0.65 (1.16%)

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CBUS

Cibus

$0.00

(0.00%)

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BA

Boeing

$355.14

4.57 (1.30%)

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FB

Facebook

$181.03

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, BA

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BA

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$355.14

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UAL

United Continental

$80.77

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SMI

SMIC

$5.23

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HPQ

HP Inc.

$20.03

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HPE

HP Enterprise

$14.36

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NVS

Novartis

$87.49

3.03 (3.59%)

CNC

Centene

$56.84

1.39 (2.51%)

WCG

WellCare

$275.45

0.99 (0.36%)

TSS

TSYS

$113.42

13.81 (13.86%)

GPN

Global Payments

$153.42

5.45 (3.68%)

HIBB

Hibbett Sports

$23.91

4.07 (20.51%)

DVAX

Dynavax

$5.77

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FL

Foot Locker

$44.39

-8.455 (-16.00%)

SPLK

Splunk

$119.13

-9.55 (-7.42%)

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VIX

Volatility Index S&P 500 Options

$0.00

(0.00%)

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

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NASDAQ market internals summary »

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$NYE

NYSE Market Internals

$0.00

(0.00%)

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NYSE market internals summary »

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RHE

Regional Health Properties

$2.06

0.09 (4.57%)

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TBIO

Translate Bio

$9.12

-0.09 (-0.98%)

16:14
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Breaking Syndicate news story on Translate Bio »

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  • 18

    Jun

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