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BCRX

BioCryst

$5.86

0.01 (0.17%)

18:08
07/25/18
07/25
18:08
07/25/18
18:08

BioCryst: Phase 2 APeX-1 trial results for BCX7353 published in NEJOM

BioCryst Pharmaceuticals announced that results from the Phase 2, APeX-1 clinical trial of BCX7353 for the prevention of attacks in patients with hereditary angioedema are published online in the July 26th issue of The New England Journal of Medicine. The APeX-1 trial was a double blind, randomized, parallel group, placebo-controlled Phase 2 dose ranging trial comparing the safety and efficacy of 28 days of once-daily BCX7353 treatment, at doses of 62.5 mg, 125 mg, 250 mg, and 350 mg, with placebo. The trial demonstrated that oral administration of BCX7353 at a dose of 125 mg or more resulted in a significantly lower rate of attacks compared with placebo. Significant benefits with respect to quality of life were observed in the 125 mg and 250 mg dose groups. Mild gastrointestinal symptoms were the principal side effect, particularly in the 250 mg and 350 mg BCX7353 dose groups. "We are extremely pleased to have these important results published in The New England Journal of Medicine," said Jon P Stonehouse, President and CEO of BioCryst. "We look forward to confirming the results from APeX-1 in our pivotal Phase 3 trial, APeX-2, which we expect to report out in the first half of 2019."

BCRX BioCryst
$5.86

0.01 (0.17%)

06/22/18
06/22/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Sunlands Online (STG) initiated with an Outperform at Credit Suisse. 2. Micron (MU) initiated with a Buy at Benchmark. 3. Interpace Diagnostics (IDXG) initiated with a Buy at Ladenburg. 4. Alteryx (AYX) initiated with an Outperform at Oppenheimer. 5. BioCryst (BCRX) initiated with a Neutral at Seaport Global. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
07/11/18
JMPS
07/11/18
NO CHANGE
Target $12
JMPS
Outperform
BioCryst shareholders voting down Idera deal not surprising, says JMP Securities
JMP Securities analyst Liisa Bayko said she was "not overly surprised" that a majority of BioCryst (BCRX) shareholders voted against the proposed merger with Idera Pharmaceuticals (IDRA) given that Idera's second most advanced program, IMO-8400 in dermatomyositis, had a Phase 2 trial failure. Bayko, who continues to believe there is a disconnect between investor and physician perceptions of the value of BCX7353 for hereditary angioedema, keeps an Outperform rating and $12 price target on BioCryst shares.
07/17/18
BOFA
07/17/18
UPGRADE
BOFA
Neutral
BioCryst upgraded to Neutral from Underperform at BofA/Merrill
07/17/18
07/17/18
UPGRADE
Target $7

Neutral
BioCryst upgraded to Neutral at BofA/Merrill
As previously reported, BofA/Merrill upgraded BioCryst to Neutral from Underperform and raised its price target to $7 from $4. Analyst Tazeen Ahmad believes proof of concept data from the Zenith trial for acute treatment of hereditary angloedema, or HAE, could be a leading indicator of future success of Phase 3 data in chronic HAE in 2019. The analyst also increased his estimates for recently launched drugs saying they could help increase the addressable treatable population.

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