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ANAB

AnaptysBio

$78.32

3.15 (4.19%)

06:58
08/07/18
08/07
06:58
08/07/18
06:58

AnaptysBio expects to report Phase 2a asthma data in Q3

AnaptysBio expects to report top-line efficacy and safety data, including improvement in Forced Expiratory Volume in One Second, from its ongoing double-blinded, placebo-controlled severe eosinophilic asthma trial Phase 2a trial, where approximately 24 adult severe eosinophilic asthma patients are treated with a 300mg intravenous single dose of etokimab versus placebo, each in combination with inhaled corticosteroids and long-acting beta agonists as background therapy, in Q3. Further, the company is enrolling a Phase 2b randomized, double-blinded, placebo-controlled, multi-dose study in 300 adult patients with moderate-to-severe atopic dermatitis, also referred to as the ATLAS clinical trial, to assess different dose levels and dosing frequencies of subcutaneously-administered etokimab for a 16-week treatment period followed by an eight-week follow-up period, with data expected in the second half of 2019.

  • 14

    Aug

ANAB AnaptysBio
$78.32

3.15 (4.19%)

04/04/18
RBCM
04/04/18
DOWNGRADE
Target $86
RBCM
Sector Perform
AnaptysBio downgraded to Sector Perform at RBC Capital on ANB020 uncertainty
As reported earlier, RBC Capital analyst Kennen MacKay downgraded AnaptysBio to Sector Perform from Outperform and lowered his price target to $86 from $144. MacKay cites "increasing skepticism regarding ANB020's path forward in peanut allergy" as post-data credibility concerns create an unfavorable risk-reward going into the company's phase 2a asthma readout expected in Q3. While the analyst expects the ANB020 readout to show a benefit vs. placebo, the results may be "challenging to interpret" relative to the treatment's competition.
05/29/18
JMPS
05/29/18
NO CHANGE
JMPS
JMP says AnaptysBio weakness ahead of asthma read-out a buying opportunity
After Aimmune Therapeutics (AIMT) presented new results from its Phase 3 trial of AR101 in peanut allergy at a medical congress, JMP Securities analyst Konstantinos Aprilakis noted that shares of competitor AnaptysBio (ANAB) are off about 42% over the last three months. He remains a buyer of AnaptysBio on any weakness going into the top-line proof of concept data from the Phase 2a trial of ANB020 in eosinophilic asthma, which is expected in Q3. The analyst, who reminds investors that he assigns about $61/share for the eosinophilic asthma indication in his valuation of AnaptysBio, maintains an Outperform rating and $180 price target on AnaptysBio shares, which closed Friday at $77.90.
07/09/18
JEFF
07/09/18
NO CHANGE
Target $145
JEFF
Buy
AnaptysBio can rally up to $30 on upcoming asthma data, says Jefferies
Jefferies analyst Biren Amin previews this quarter's readout of AnaptysBio's Phase IIa study testing ANB020 in severe asthma. The analyst's analysis suggests most biologics deliver 6%-9% improvement in lung function. A 7%-8% improvement likely drives $15-$20 of share upside while 9%-10% likely pushes the stock up $25-$30, Amin tells investors in a research note. He believes a the lower range of a 5%-6% improvement could trigger a selloff of $10-$15 per share and a true miss of less than 5% improvement could see the stock down $20-$25. He keeps a Buy rating on AnaptysBio with a $145 price target.
07/19/18
FBCO
07/19/18
INITIATION
Target $104
FBCO
Outperform
AnaptysBio initiated with an Outperform at Credit Suisse
Credit Suisse initiated AnaptysBio with an Outperform and $104 price target.

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