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MDGL

Madrigal Pharmaceuticals

$246.59

-4.69 (-1.87%)

07:40
08/07/18
08/07
07:40
08/07/18
07:40

Madrigal sees 'high likelihood of success' for Phase 3 MGL-3196 study

"We believe the 36-week data from our recently completed Phase 2 clinical study of MGL-3196 in patients with NASH suggest a high likelihood of success in a similarly designed Phase 3 study, for which we are actively preparing, pending regulatory agreement," stated Paul Friedman, CEO of Madrigal Pharmaceuticals in this morning's earnings release. "With our financial raise completed, which provided more than $300 million of additional capital, we are in a strong position to expedite the MGL-3196 development program in NASH and dyslipidemias." Added Becky Taub, CMO and Executive VP, Research & Development, "We believe the totality of data from our clinical and preclinical studies to date, including the consistency of the various parameters related to clinical benefits and safety, demonstrate the potential of MGL-3196 to resolve NASH and improve multiple atherogenic lipids. We are pleased our abstract was selected by AASLD as an oral presentation in the presidential plenary clinical session and look forward to presenting these encouraging clinical outcomes in November at The Liver Meeting 2018."

MDGL Madrigal Pharmaceuticals
$246.59

-4.69 (-1.87%)

06/28/18
RAJA
06/28/18
INITIATION
RAJA
Market Perform
Madrigal Pharmaceuticals initiated with a Market Perform at Raymond James
07/12/18
CANT
07/12/18
INITIATION
Target $59
CANT
Overweight
Cantor puts $59 price target on 'undervalued' NASH play Galmed
Cantor Fitzgerald analyst Elemer Piros last night initiated coverage of Galmed Pharmaceuticals (GLMD) with an Overweight rating and $59 price target. The stock closed yesterday down 45c to $10.55. The company is developing Aramchol, a novel, once-daily, oral therapy to treat liver diseases using fattyacid/bile-acid conjugates, Piros tells investors in a research note. The analyst believes that by Q4 of 2019, only three meaningful non-alcoholic steatohepatitis pivotal programs will be in development: Allergan's (AGN) cenicriviroc, Madrigal Pharmaceuticals' (MDGL) MGL-3196, and Galmed's Aramchol. Of the three drugs, Galmed's has the highest likelihood of achieving improvement on NASH resolution without worsening of fibrosis, and improvement in fibrosis score without worsening of NASH, Piros argues. He believes Galmed is undervalued relative to peers in the NASH space.
08/06/18
GSCO
08/06/18
DOWNGRADE
Target $314
GSCO
Neutral
Madrigal Pharmaceuticals downgraded to Neutral from Buy at Goldman Sachs
Goldman Sachs analyst Salveen Richter downgraded Madrigal Pharmaceuticals to Neutral with an unchanged price target of $314. The stock closed Friday down 41c to $250.93. The analyst continues to view MGL-3196 as a "best-in-industry, next-generation drug" for nonalcoholic steatohepatitis. However, with the stock up 173% year-to-date, he believes Madrigal is entering a "period of limited value-driving catalysts." Richter, while admitting a buyout could occur, sees limited upside in the shares.
08/06/18
GSCO
08/06/18
UPGRADE
Target $157
GSCO
Buy
Intercept upgraded to Buy from Sell at Goldman Sachs
Goldman Sachs analyst Salveen Richter double upgraded Intercept Pharmaceuticals (ICPT) to Buy from Sell and raised his price target for the shares to $157 from $46. The stock closed Friday down 3.5%, or $3.57, to $97.26. The analyst says Ocaliva in fatty liver disease nonalcoholic steatohepatitis is the crux of Intercept's value proposition and that he's positive into the Phase 3 Regenerate interim readout in the first half of 2019. Richter this morning also downgraded Madrigal Pharmaceuticals (MDGL) to Neutral from Buy. He believes, however, that Madrigal's MGL-3196 is a "best-in-industry, next-generation" drug for nonalcoholic steatohepatitis. The analyst expects Intercept's Ocaliva will achieve one or both of the Phase 3 co-primary endpoints of NASH resolution and fibrosis improvement. He sees share upside of 60%-plus as the first half of 2019 catalyst approaches. Intercept should benefit from Ocaliva's global first-mover advantage in NASH, Richter tells investors in a research note. Goldman estimates peak global sales of NASH drugs to be $3.7B.

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WMT

Walmart

$97.89

-0.74 (-0.75%)

13:37
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TCEHY

Tencent

$0.00

(0.00%)

13:26
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13:26
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Tencent-backed Qutoutiao files for U.S. IPO, Reuters reports »

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FB

Facebook

$173.78

-0.98 (-0.56%)

, AMZN

Amazon.com

$1,881.94

-5.56 (-0.29%)

13:10
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Periodicals
Selloff in Chinese internet stocks may shake faith in FANG, Reuters says »

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FB

Facebook

$173.78

-0.98 (-0.56%)

AMZN

Amazon.com

$1,881.94

-5.56 (-0.29%)

NFLX

Netflix

$316.78

-5.51 (-1.71%)

GOOG

Alphabet

$1,199.79

-6.21 (-0.51%)

GOOGL

Alphabet Class A

$1,215.50

-8.05 (-0.66%)

TCEHY

Tencent

$0.00

(0.00%)

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VLKAY

Volkswagen

$0.00

(0.00%)

13:05
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13:05
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13:05
Periodicals
Volkswagen CEO was told about emissions software months before, Reuters reports »

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WMT

Walmart

$97.89

-0.74 (-0.75%)

, TCEHY

Tencent

$0.00

(0.00%)

13:01
08/18/18
08/18
13:01
08/18/18
13:01
Hot Stocks
Walmart, Flipkart announce completion of investment »

Walmart (WMT) and…

WMT

Walmart

$97.89

-0.74 (-0.75%)

TCEHY

Tencent

$0.00

(0.00%)

MSFT

Microsoft

$107.58

-0.07 (-0.07%)

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BBOX

Black Box

$1.64

0.09 (5.81%)

12:57
08/18/18
08/18
12:57
08/18/18
12:57
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Black Box announces sale agreement of Federal Government IT Services Business »

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KSS

Kohl's

$76.43

1.68 (2.25%)

12:52
08/18/18
08/18
12:52
08/18/18
12:52
Periodicals
Kohl's looking to break cycle, Barron's says »

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  • 21

    Aug

STT

State Street

$84.95

0.73 (0.87%)

12:47
08/18/18
08/18
12:47
08/18/18
12:47
Periodicals
State Street selloff looks overdone, Barron's says »

At the moment, State…

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WMT

Walmart

$97.89

-0.74 (-0.75%)

, AMZN

Amazon.com

$1,881.94

-5.56 (-0.29%)

12:42
08/18/18
08/18
12:42
08/18/18
12:42
Periodicals
May be time to sell Walmart, Barron's says »

In a follow-up story,…

WMT

Walmart

$97.89

-0.74 (-0.75%)

AMZN

Amazon.com

$1,881.94

-5.56 (-0.29%)

03/08/13
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  • 13

    Sep

VZ

Verizon

$54.79

0.51 (0.94%)

12:39
08/18/18
08/18
12:39
08/18/18
12:39
Periodicals
Verizon remains 'reasonably' priced, Barron's says »

In a follow-up story,…

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CF

CF Industries

$47.52

0.25 (0.53%)

, MOS

Mosaic

$29.64

(0.00%)

12:36
08/18/18
08/18
12:36
08/18/18
12:36
Periodicals
CF, Mosaic gains have just begun, Barron's says »

CF Industries (CF),…

CF

CF Industries

$47.52

0.25 (0.53%)

MOS

Mosaic

$29.64

(0.00%)

NTR

Nutrien

$55.95

0.94 (1.71%)

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  • 11

    Sep

  • 06

    Nov

ABBV

AbbVie

$98.79

0.6 (0.61%)

, LYB

LyondellBasell

$113.07

1.155 (1.03%)

12:25
08/18/18
08/18
12:25
08/18/18
12:25
Periodicals
StAbbVie, Starbucks among dividend standouts, Barron's says »

AbbVie (ABBV),…

ABBV

AbbVie

$98.79

0.6 (0.61%)

LYB

LyondellBasell

$113.07

1.155 (1.03%)

AVGO

Broadcom

$209.27

0.6 (0.29%)

RF

Regions Financial

$19.48

0.09 (0.46%)

SBUX

Starbucks

$53.58

0.53 (1.00%)

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BV

BrightView

$17.49

-0.06 (-0.34%)

12:21
08/18/18
08/18
12:21
08/18/18
12:21
Periodicals
Sunny outlook for BrightView, Barron's says »

BrightView's stock…

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HOG

Harley-Davidson

$42.26

1.15 (2.80%)

, CSIQ

Canadian Solar

$13.12

0.02 (0.15%)

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Week in review: How Trump's policies moved stocks »

Catch up on the top…

HOG

Harley-Davidson

$42.26

1.15 (2.80%)

CSIQ

Canadian Solar

$13.12

0.02 (0.15%)

FSLR

First Solar

$50.98

0.18 (0.35%)

JASO

JA Solar

$0.00

(0.00%)

SUNEQ

SunEdison

$0.00

(0.00%)

SPWR

SunPower

$6.65

0.06 (0.91%)

TSL

Trina Solar

$0.00

(0.00%)

YGE

Yingli Green Energy

$0.00

(0.00%)

PEP

PepsiCo

$114.98

0.7 (0.61%)

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  • 02

    Oct

LYV

Live Nation

$48.15

-0.53 (-1.09%)

17:46
08/17/18
08/17
17:46
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17:46
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Live Nation CFO discloses sale of 40K shares of common stock »

Live Nation CFO Elizabeth…

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XLE

Energy Select Sector SPDR

$72.63

0.21 (0.29%)

, XLU

Utilities SPDR

$54.50

0.25 (0.46%)

17:40
08/17/18
08/17
17:40
08/17/18
17:40
General news
Week ending ETF Scorecard: Consumer Staples outperforms, Energy skids »

S&P500 SECTORS:…

XLE

Energy Select Sector SPDR

$72.63

0.21 (0.29%)

XLU

Utilities SPDR

$54.50

0.25 (0.46%)

IYR

DJ US Real Estate Index Fund

$83.16

0.765 (0.93%)

XLP

Consumer Staples Sector SPDR

$55.02

0.39 (0.71%)

XLY

Consumer Discretionary Sector SPDR

$112.51

0.11 (0.10%)

XLB

S&P Select Materials SPDR

$58.41

0.41 (0.71%)

XLF

Financial Select Sector

$28.16

0.055 (0.20%)

XLV

Health Care Select Sector SPDR

$91.12

0.33 (0.36%)

XLK

Technology Select Sector SPDR

$73.17

0.14 (0.19%)

XLI

Industrial Select Sector SPDR

$76.26

0.47 (0.62%)

GLD

SPDR Gold Trust

$112.12

1.01 (0.91%)

SLV

iShares Silver Trust

$13.93

0.16 (1.16%)

USO

United States Oil Fund

$13.70

0.065 (0.48%)

UNG

United States Natural Gas Fund

$24.18

0.295 (1.24%)

HYG

iShares iBoxx $ High Yield Corporate Bond

$86.03

0.08 (0.09%)

LQD

iShares iBoxx $ Investment Grade Corporate Bond

$115.97

0.11 (0.09%)

TLT

iShares 20+ Year Treasury Bond Fund

$120.99

0.16 (0.13%)

IEF

iShares 7-10 Year Treasury Bond ETF

$102.49

0.04 (0.04%)

SHY

iShares 1-3 Year Treasury Bond

$83.28

0.03 (0.04%)

IWD

iShares Russell 1000 Value

$126.16

0.6 (0.48%)

IWF

iShares Russell 1000 Growth

$150.80

0.27 (0.18%)

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GLD

SPDR Gold Trust

$112.12

1.01 (0.91%)

17:33
08/17/18
08/17
17:33
08/17/18
17:33
Hot Stocks
SPDR Gold Trust holdings fall to 772.24MT from 773.41MT »

This is the 5th…

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GDOT

Green Dot

$85.04

0.37 (0.44%)

17:30
08/17/18
08/17
17:30
08/17/18
17:30
Hot Stocks
Green Dot exec Dent sells 7,754 common shares »

In a regulatory filing,…

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  • 25

    Sep

SMSI

Smith Micro

$2.49

-0.01 (-0.40%)

17:17
08/17/18
08/17
17:17
08/17/18
17:17
Syndicate
Breaking Syndicate news story on Smith Micro »

Smith Micro files to sell…

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NDRA

ENDRA Life Sciences

$2.70

0.2 (8.00%)

17:14
08/17/18
08/17
17:14
08/17/18
17:14
Syndicate
Breaking Syndicate news story on ENDRA Life Sciences »

ENDRA Life Sciences files…

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BA

Boeing

$346.44

0.55 (0.16%)

17:10
08/17/18
08/17
17:10
08/17/18
17:10
Hot Stocks
Boeing awarded $152.5M U.S. Navy contract »

Boeing is awarded a…

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BA

Boeing

$346.44

0.55 (0.16%)

17:09
08/17/18
08/17
17:09
08/17/18
17:09
Hot Stocks
Boeing awarded $217M Defense Department contract »

The Boeing Co has been…

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LLL

L3 Technologies

$210.37

0.56 (0.27%)

17:08
08/17/18
08/17
17:08
08/17/18
17:08
Hot Stocks
L3 Technologies awarded $240M Defense Department contract »

L-3 Communications was…

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HSGX

Histogenics

$2.65

-0.05 (-1.85%)

17:06
08/17/18
08/17
17:06
08/17/18
17:06
Syndicate
Breaking Syndicate news story on Histogenics »

Histogenics files $75M…

03/08/13
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PLD

Prologis

$67.45

1.79 (2.73%)

, DCT

DCT Industrial

$68.77

1.805 (2.70%)

16:58
08/17/18
08/17
16:58
08/17/18
16:58
Conference/Events
DCT Industrial to host special shareholder meeting »

Special Shareholder…

PLD

Prologis

$67.45

1.79 (2.73%)

DCT

DCT Industrial

$68.77

1.805 (2.70%)

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