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ONCE

Spark Therapeutics

$55.29

-22.34 (-28.78%)

12:54
08/07/18
08/07
12:54
08/07/18
12:54

Spark Therapeutics price target lowered to $55 from $74 at Leerink

Leerink analyst Joseph Schwartz lowered his price target for Spark Therapeutics to $55 from $74 based on a reduction in his PoS for SPK-8011 to 15% from 25% previously. The analyst notes that SPK-8011 in hemophilia A continues to miss its target product profile of consistent factor VIII expression above 12% of normal levels, confirming his concerns about immunogenicity to the SPK-100 vector which arose after the first SPK-8011 data update at ASH 2017. Schwartz reiterates a Market Perform rating on the shares.

  • 07

    Aug

  • 10

    Sep

ONCE Spark Therapeutics
$55.29

-22.34 (-28.78%)

08/07/18
PIPR
08/07/18
NO CHANGE
Target $120
PIPR
Overweight
BioMarin competitive positioning 'improved measurably,' says Piper Jaffray
Spark Therapeutics' (ONCE) update this morning for hemophilia A candidate SPK-8011 was disappointing both efficacy- and safety-wise, Piper Jaffray analyst Christopher Raymond tells investors in a research note titled "Spark Fails to Ignite; Valrox Competitive Positioning Just Improved Measurably." He believes the news "goes a long way" to putting this potential threat to BioMarin (BMRN) "to bed." The analyst is incrementally positive on BioMarin's competitive positioning in hemophilia A and keeps an Overweight rating on the shares with a $120 price target. The Spark data compares unfavorably to BioMarin's valrox, Raymond writes. He remains a buyer of BioMarin with an Overweight rating and $120 price target. The stock in premarket trading is up $5.55 to $103.50.
08/07/18
SBSH
08/07/18
UPGRADE
SBSH
Buy
Spark Therapeutics upgraded to Buy from Neutral at Citi
08/07/18
SBSH
08/07/18
UPGRADE
SBSH
Buy
Citi upgrades Spark Therapeutics to Buy with shares down nearly 30%
Citi analyst Mohit Bansal upgraded Spark Therapeutics to Buy from Neutral amid today's post-earnings selloff. The analyst maintains an $85 price target for the shares. The company's update this morning on its hemophilia A gene therapy was "incrementally positive and better than our expectations," Bansal tells investors in a research note. The analyst feels investors should not be too concerned about the immune flare in two patients as he thinks these patients could be managed with prophylactic use of steroids. Other gene therapy players are using prophylactic steroids and it was a bit surprising that Spark did not use prophylactic steroid in the first place, the analyst writes. He views today's selloff as a buying opportunity saying the data in five of seven patients are better than his expectations. Bansal notes that Spark will employ a prophy strategy going forward. The analyst also views the company as a potential takeover candidate. He pegs Spark's buyout valuation at $130 per share. The stock in midday trading is down 29%, or $22.49, to $55.12.
08/07/18
LEER
08/07/18
NO CHANGE
Target $55
LEER
Market Perform
Spark Therapeutics price target lowered to $55 from $74 at Leerink

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