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IONS

Ionis Pharmaceuticals

$43.25

-0.41 (-0.94%)

13:49
08/07/18
08/07
13:49
08/07/18
13:49

Piper Jaffray keeps Neutral rating on Ionis with 'glass half full' view

Piper Jaffray analyst Tyler Van Buren said he is keeping his "glass half full" Neutral rating on Ionis after the company reported Q2 results and provided updates on its clinical programs. Waylivra and Tegsedi represent "exciting" opportunities with $1B+ in peak global sales potential by 2025, but Van Buren said attention should be paid to the early launch metrics to gain additional confidence in their ultimate commercial success. The analyst has a $50 price target on Ionis shares.

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IONS Ionis Pharmaceuticals
$43.25

-0.41 (-0.94%)

06/20/18
LEHM
06/20/18
NO CHANGE
LEHM
Barclays upgrades PTC to Equal Weight, downgrades Ionis to Underweight
Barclays analyst Gena Wang upgraded PTC Therapeutics (PTCT) to Equal Weight from Underweight while downgrading Ionis Pharmaceuticals (IONS) to Underweight from Equal Weight. The analyst raised her price target on the former to $40 from $26 and lowered her price target on the latter to $45 from $52. Following PTC's new data in spinal muscular atrophy data, the analyst believes its risdiplam has "disruptive potential" to Ionis and Biogen's (BIIB) Spinraza.
07/11/18
PIPR
07/11/18
NO CHANGE
Target $50
PIPR
Neutral
Ionis approval narrower than expected, says Piper Jaffray
Piper Jaffray analyst Tyler Van Buren says the European approval of Tegsedi announced this morning Ionis Pharmaceuticals (IONS) and Akcea Therapeutics (AKCA) for the treatment of stage 1 or stage 2 polyneuropoathy in adult patients with hATTR was narrower than he originally expected. The indication is narrower than the broader hATTR patient population, inclusive of both cardiomyopathy and polyneuropathy, but makes sense considering that the pivotal trial primarily enrolled patients with stage 1 and 2 polyneuropathy, Van Buren tells investors in a research note. The analyst adds that while the approval is a positive development and Tegsedi represents the largest near-term pipeline opportunity for Ionis, he wants to observe positive early launch metrics and confirmation of the opportunity before getting more constructive on the shares. He keeps a Neutral rating on Ionis with a $50 price target.
07/23/18
OPCO
07/23/18
NO CHANGE
Target $400
OPCO
Outperform
Oppenheimer anticipating potential volatility ahead for Biogen
Oppenheimer analyst Jay Olson anticipates Biogen (BIIB) volatility driven by Q2 results along with AD presentations at AAIC that include promising BAN2401 data, which was recently top-lined. The analyst expects a focus on ADCOMS component scores and effect sizes for BAN2401. With regards to Q2 results, Olson expects top-line growth of 4% and non-GAAP EPS of $3.95 which is impacted by the Ionis Pharmaceuticals (IONS) deal upfront payment. Additionally, he expects continued strong Spinraza and biosimilar growth. Olson reiterates an Outperform rating and $400 price target on Biogen's shares.
08/07/18
STFL
08/07/18
INITIATION
Target $48
STFL
Hold
Ionis Pharmaceuticals transferred with a Hold at Stifel
Stifel transferred coverage of Ionis Pharmaceuticals (IONS) to analyst Paul Matteis, who set a Hold rating and $48 price target on the shares. The Biogen (BIIB) deal, while validating, limits some of the future upside for Ionis, Matteis tells investors. Also, despite his long-term bullishness on the TTR amyloidisis opportunity, he is below consensus for the first year of the launches for Tegsedi and Waylivra.

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