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ALNY

Alnylam

$97.40

3.13 (3.32%)

13:08
08/10/18
08/10
13:08
08/10/18
13:08

Alnylam's Onpattro approved by FDA to treat polyneuropathy caused by hATTR

The U.S. Food and Drug Administration approved Onpattro infusion for the treatment of peripheral nerve disease, or polyneuropathy, caused by hereditary transthyretin-mediated amyloidosis, or hATTR, in adult patients. This is the first FDA-approved treatment for patients with polyneuropathy caused by hATTR, a rare, debilitating and often fatal genetic disease characterized by the buildup of abnormal amyloid protein in peripheral nerves, the heart and other organs, the agency noted. Approval of Onpattro was granted to Alnylam Pharmaceuticals.

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ALNY Alnylam
$97.40

3.13 (3.32%)

08/03/18
PIPR
08/03/18
NO CHANGE
Target $160
PIPR
Overweight
Piper sees FDA approval for Alnylam August 11 action date
Piper Jaffray analyst Edward Tenthoff is encouraged by the "broad opinion" from the U.K.'s Medicines and Healthcare Products Regulatory Agency for hATTR amyloidosis. The analyst continues to expect FDA approval of Onpattro to treat hATTR amyloidosis by next Saturday's August 11 action date. Tenthoff reiterates an Overweight rating on Alnylam Pharmaceuticals with a $160 price target.
08/06/18
STFL
08/06/18
UPGRADE
STFL
Buy
Alnylam upgraded to Buy from Hold at Stifel
08/07/18
08/07/18
UPGRADE
Target $125

Buy
Alnylam upgraded to Buy with $125 price target at Stifel
As previously reported, Stifel transferred coverage of Alnylam to analyst Paul Matteis, who set a Buy rating and $125 price target on the shares, up from the firm's prior Hold rating. He cites a series of upcoming, likely positive pipeline events for givosiran, lumasiran and ALN-TTRsc02 along with his confidence in Alnylam's ability to have a dominant position in the TTR amyloidosis market over the longer-term.
08/07/18
08/07/18
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. SeaWorld (SEAS) upgraded to Neutral from Underperform at Macquarie with analyst Matthew Brooks saying management is executing well, 1H 2018 attendance growth was impressive, and a new 2020 EBITDA goal heading into a seasonally strong period changes is cautious thesis. 2. Alnylam (ALNY) upgraded to Buy from Hold at Stifel with analyst Paul Matteis citing a series of upcoming, likely positive pipeline events for givosiran, lumasiran and ALN-TTRsc02 along with his confidence in Alnylam's ability to have a dominant position in the TTR amyloidosis market over the longer-term. 3. NeoPhotonics (NPTN) upgraded to Buy from Neutral at B. Riley FBR with analyst Dave Kang saying he sees improving fundamentals and increased his estimates following the company's Q2 results. 4. Illumina (ILMN) upgraded to Equal Weight from Underweight at Morgan Stanley with analyst Steve Beuchaw saying his prior thesis overestimated the impact of new products such as NovaSeq on utilization of the legacy installed base and failed to value critical new markets. 5. MasTec (MTZ) upgraded to Outperform from Neutral at Baird with analyst Andrew Wittmann saying concerns of weak cash flow and the MVP project work stoppage have already been priced into the stock and now offer a potential catalyst for the shares. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

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SITO

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LHCG

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3.08 (3.31%)

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REDU

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EHC

Encompass Health

$72.31

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HTHT

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$28.59

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UHS

Universal Health

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HTHT

Huazhu Group

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HTHT

Huazhu Group

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REDU

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$10.20

-0.22 (-2.11%)

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Earnings
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PEP

PepsiCo

$116.81

0.14 (0.12%)

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AMH

American Homes 4 Rent

$19.87

-0.42 (-2.07%)

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UNVR

Univar

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BMY

Bristol-Myers

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KAMN

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WMT

Walmart

$99.62

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QURE

uniQure

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INTC

Intel

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TGT

Target

$80.76

-2.35 (-2.83%)

16:31
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Initiation
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NVDA

Nvidia

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