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VRTX

Vertex

$176.04

0.98 (0.56%)

05:22
08/20/18
08/20
05:22
08/20/18
05:22

Vertex receives 'positive' PBAC recommendation for reimbursement of Orkambi

Vertex Pharmaceuticals announces that it has received the Pharmaceutical Benefits Advisory Committee's, or PBAC, recommendation for Orkambi to be listed on the Pharmaceutical Benefits Scheme, or PBS, in Australia for people ages six and over with cystic fibrosis, or CF, who have two copies of the F508del mutation in the cystic fibrosis transmembrane conductance regulator gene. Lumacaftor/ivacaftor is the first medicine to treat the underlying cause of CF in people ages six and older who have two copies of the F508del mutation.

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VRTX Vertex
$176.04

0.98 (0.56%)

07/27/18
PIPR
07/27/18
NO CHANGE
Target $230
PIPR
Overweight
Piper says Vertex faces 'onerous task' getting reimbursement for Symkevi in EU
After the EMA announced earlier that the CHMP adopted a positive opinion on Symkevi, Piper Jaffray analyst Edward Tenthoff said he expects EMA approval within the next few months, after which Vertex will face the "onerous task" of gaining European reimbursement. The analyst, who anticipates KALYDECO and ORKAMBI label expansions with PDUFA dates in August to continue to drive CF sales growth this year, keeps his Overweight rating and $230 price target on Vertex shares.
08/07/18
STFL
08/07/18
INITIATION
Target $200
STFL
Buy
Vertex transferred with a Buy at Stifel
Stifel transferred coverage of Vertex to analyst Paul Matteis, who set a Buy rating and $200 price target on the shares. Matteis thinks Vertex continues to build strong barriers to entry that in Cystic Fibrosis and believes that the company's non-CF pipeline largely represents upside to the stock.
08/07/18
PIPR
08/07/18
NO CHANGE
Target $20
PIPR
Overweight
Eloxx Pharma's ELX-02 can address significant unmet need, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff kept his Overweight rating and $20 price target on Eloxx Pharmaceuticals (ELOX) after its Q2 earnings, saying the company's cash position of $63.4M is expected to keep it funded into 2020. The analyst notes that having cleared its pre-clinical trial application in Belgium, the company is preparing to initiate a Phase 2 study of ELX-02 in cystic fibrosis with G542X mutation in Q4, anticipating a readout in 2019. Tenthoff notes that Eloxx Pharma has an opportunity for the program given that up to 15% of CF patients do not respond to the current therapies offered by Vertex (VRTX).
08/08/18
HCWC
08/08/18
NO CHANGE
Target $43
HCWC
Buy
Insmed likely to be acquired after positive panel vote, says H.C. Wainwright
H.C. Wainwright analyst Andrew Fein raised his price target for Insmed (INSM) to $43 from $35 following yesterday's 12-2 FDA panel vote in favor of ALIS in refractory nontuberculous mycobacterial patients. Insmed is now likely to be acquired as ALIS "fits well within the pipeline of a number of larger companies," Fein tells investors in a research note. He expects the company's Q3 conference call "may well be its last." The analyst sees AstraZeneca (AZN), Gilead Sciences (GILD) and Vertex Pharmaceuticals (VRTX) as potential acquirers of Insmed. He reiterates a Buy rating on Insmed.

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CTRP

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$37.63

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ESV

Ensco Rowan

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AMGN

Amgen

$171.29

1.67 (0.98%)

, GILD

Gilead

$66.51

-0.01 (-0.02%)

17:30
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Upgrade
Amgen, Gilead, Alexion, Vertex, BioMarin, Biogen, Regeneron rating change  »

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AMGN

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$171.29

1.67 (0.98%)

GILD

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$66.51

-0.01 (-0.02%)

ALXN

Alexion

$127.47

-1.33 (-1.03%)

VRTX

Vertex

$172.37

3.22 (1.90%)

BMRN

BioMarin

$87.80

0.33 (0.38%)

BIIB

Biogen

$234.98

2.04 (0.88%)

REGN

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$320.00

10.19 (3.29%)

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