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XENE

Xenon Pharmaceuticals

$12.20

(0.00%)

06:11
08/29/18
08/29
06:11
08/29/18
06:11

Xenon Pharmaceuticals' XEN1101 shows 'positive' results in Phase 1b study

Xenon Pharmaceuticals announced 'positive' data from its XEN1101 Phase 1b transcranial magnetic stimulation study. XEN1101 is a Kv7 potassium channel opener being developed by Xenon for the treatment of epilepsy. Results will be presented in a podium presentation at the 13th European Congress on Epileptology being held in Vienna. The completed Phase 1b TMS study suggested XEN1101 has an ability to inhibit cortical excitability, an important CNS effect observed with approved anti-epileptic drugs. XEN1101 was well tolerated with all adverse events reported as mild or moderate and reversible. In addition to completing both the Phase 1a pilot and Phase 1b TMS studies, Xenon has now completed enrollment in the XEN1101 Phase 1 clinical trial using a powder-in-capsule formulation, which is evaluating the safety, tolerability and pharmacokinetics of both single ascending doses and multiple ascending doses of XEN1101. A Phase 2 clinical trial in adult focal seizures expected to be initiated in Q4.

XENE Xenon Pharmaceuticals
$12.20

(0.00%)

03/22/18
JEFF
03/22/18
NO CHANGE
Target $6
JEFF
Buy
Xenon Pharmaceuticals price target raised to $6 from $5 at Jefferies
Jefferies analyst Maury Raycroft raised his price target for Xenon Pharmaceuticals to $6 and keeps a Buy rating on the shares after traveling with management. The analyst sees 2018 as a key year for the company with data readouts in epilepsy. Initial data in May will likely move the stock, Raycroft tells investors in a research note.
06/13/18
JEFF
06/13/18
NO CHANGE
Target $9
JEFF
Buy
Sage update yesterday positive for Xenon, says Jefferies
Jefferies analyst Maury Raycroft believes Sage Therapeutics' (SAGE) FDA approval to accelerate a development path for '217 in major depressive disorder and postpartum depression provides a positive read-through for Xenon Pharmaceuticals (XENE). Xenon has two epilepsy programs and one program for hemiplegic migraine, which all have potential in rare disease indications with broader applicability, Raycroft tells investors in a research note. He believes "recent derisking" provides a "great entry point" into Xenon Pharmaceuticals at current share levels. The analyst has a Buy rating on the shares with a $9 price target.

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PBR

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BK

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