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MNKD

MannKind

$1.71

0.02 (1.18%)

09:07
09/24/18
09/24
09:07
09/24/18
09:07

MannKind completes cohort 1, opens enrollment of cohort 2 for Afrezza study

MannKind announced that cohort 2 of the Afrezza safety and pharmacokinetics study in pediatric patients is now open for enrollment. The first group of individuals participating in the ongoing pediatric study of Afrezza, which included adolescents with type 1 diabetes aged 13-17 years old, was recently completed. The study findings to date support that the single-dose pharmacokinetic, or PK, profile of insulin levels for this age group is consistent with patterns seen in adult patients. In addition, dosing over a one-month period demonstrated a safety profile consistent with that observed in adults. As a result of these findings, MannKind and the study investigators are proceeding with enrollment of the second cohort of subjects. The second cohort will study Afrezza in children aged 8-12 years and will assess PK, as well as the short-term safety and tolerability of multiple doses of Afrezza.

  • 01

    Oct

MNKD MannKind
$1.71

0.02 (1.18%)

06/07/18
HCWC
06/07/18
NO CHANGE
Target $5
HCWC
Buy
MannKind's treprostinil could be 'transformational asset,' says H.C. Wainwright
MannKind's (MNKD) announcement this morning of a successful Phase 1 completion of its Technosphere treprostinil dry powder inhalation for pulmonary arterial hypertension comes months ahead of schedule, H.C. Wainwright analyst Oren Livnat tells investors in a research note. The news is an important reminder that MannKind's inhalation drug delivery platforms offer potentially much more value than just Afrezza inhalable insulin, the analyst contends. He believes inhalable treprostinil, which is not yet in his model, could "ultimately prove a transformational asset." Livnat points out that United Therapeutics' (UTHR) pulmonary arterial hypertension treprostinil franchise is estimated to deliver over $1.1B of sales in 2018. The analyst keeps a Buy rating on MannKind with a $5 price target.
06/26/18
HCWC
06/26/18
NO CHANGE
Target $5
HCWC
Buy
MannKind gained 'new credibility' for Afrezza at ADA, says H.C. Wainwright
H.C. Wainwright analyst Oren Livnat said MannKind materially increased Afrezza's relevance and gained "new credibility" with multiple data presentations, including a well-attended symposium and oral presentation, at the American Diabetes Association meeting that was just held. He called the event an "eye-opening experience" that showed Afrezza's defining differentiation is not that it is inhalable, but that it "really is the best meal-time insulin, full stop." Following the ADA event, Livnat reiterated his Buy rating and $5 target on MannKind shares.
08/03/18
HCWC
08/03/18
NO CHANGE
Target $4
HCWC
Buy
MannKind price target lowered to $4 from $5 at H.C. Wainwright
H.C. Wainwright analyst Oren Livnat lowered his price target for MannKind to $4 citing the company's "light" Q2 results. The analyst, however, still models for an Afrezza ramp in the second half of the year. He remains remain "very bullish long-term if the product can be resourced" and keeps a Buy rating on MannKind.
09/05/18
HCWC
09/05/18
NO CHANGE
Target $4
HCWC
Buy
MannKind valuation 'floor' raised with United deal, says H.C. Wainwright
H.C. Wainwright analyst Oren Livnat says United Therapeutics (UTHR) is the "ideal partner" for MannKind (MNKD) to develop and commercialize technosphere treprostinil dry powder inhalation for pulmonary arterial hypertension. The deal announced yesterday represents additional validation of MannKind's "underappreciated" DPI and delivery platforms beyond Afrezza, Livnat tells investors in a research note. Importantly, the deal brings in non-dilutive financing, "raises the floor" on MannKind's valuation, and "offers a new path to potential long-term upside from here even if Afrezza never reaches the potential we think it deserves," Livnat writes. The analyst reiterates a Buy rating on MannKind shares with a $4 price target. The stock closed yesterday up 89%, or 98c, to $2.08.

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