Yield10 Bioscience receives positive response from USDA-APHIS's BRS
Yield10 Bioscience announced that it has received a positive response from the USDA-APHIS's Biotechnology Regulatory Services, or BRS, confirming that its genome-edited Camelina sativa plant lines developed using CRISPR-Cas9 for increased oil content are not regulated articles under BRS regulations. This clarification of the regulatory status of the triple genome-edited Camelina plant lines accelerates the path to conducting field trials in the United States in 2019. Preliminary results obtained by Yield10 in greenhouse studies suggest that the triple-edited Camelina lines may have the potential to increase oil content and to improve the quality of the oil. Yield10 intends to study these plant lines in field tests planned for 2019 in the U.S. as part of its development program to increase oil and seed yield in Camelina and canola for specialty oils applications. The APHIS BRS determination will allow Yield10 Bioscience to conduct field testing of its genome-edited Camelina outside of the Part 340 regulations for genetically engineered organisms. APHIS also noted in its response letter that "the genetic change" of the genome-edited Camelina lines "would not increase its weediness" However, the company will still be required to follow any EPA or FDA regulations that may be applicable to the modified plant line.