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CLVS

Clovis

$32.14

2.985 (10.24%)

10:53
10/02/18
10/02
10:53
10/02/18
10:53

JPMorgan increasingly confident in Clovis Oncology's rucaparib

JPMorgan analyst Cory Kasimov is encouraged by Clovis Oncology's announcement this morning that rucaparib received breakthrough designation from the FDA for the third line treatment of patients with BRCA mutated metastatic castrate-resistant prostate cancer on the basis of data from the Triton-2 study. The analyst says the news further increases his confidence in the potential for rucaparib to produce response rates that are meaningfully better than currently available options. His model implies $9 per share for prostate, assuming a 55% probability of success and $450M in peak unadjusted sales. Kasimov keeps an Overweight rating on Clovis, which is up 11%, or $3.33, to $32.47 in morning trading.

CLVS Clovis
$32.14

2.985 (10.24%)

09/17/18
PIPR
09/17/18
NO CHANGE
Target $35
PIPR
Neutral
Piper sees Astra's Lynparza as 'much cleaner' than Tesaro's Zejula
Piper Jaffray analyst Christopher Raymond reiterates a Neutral rating and $35 price target on Tesaro (TSRO) after analyzing a year's worth of adverse event reporting as captured by FDA's Adverse Event Reporting System database, which he obtained through a Freedom of Information Act request. The analyst, while cautioning that the database "likely contains inaccuracies and is far from perfect," is "struck by how much cleaner" AstraZeneca's (AZN) Lynparza appears versus Tesaro's Zejula and Clovis Oncology's (CLVS) Rubraca. Further, Raymond is also surprised that Zejula's adverse events rates do not appear to have decreased in any meaningful way year-over-year, despite Tesaro's active down-dosing efforts. Since the analyst thinks PARPi differentiation remains largely around safety, he lowered his Zejula estimates in 2019 and beyond. Lynparza is likely to maintain the upper hand, Raymond tells investors in a research note.
09/17/18
GUGG
09/17/18
INITIATION
Target $75
GUGG
Buy
Clovis initiated with a Buy at Guggenheim
Target $75.
09/21/18
JPMS
09/21/18
NO CHANGE
Target $71
JPMS
Overweight
Clovis price target lowered to $71 from $87 at JPMorgan
JPMorgan analyst Cory Kasimov lowered his price target for Clovis Oncology to $71 after "reigning in" his ovarian expectations but keeps an Overweight rating on the shares. With the European Society of Medical Oncology meeting coming up in October, Kasimov is previewing the first look at data from Clovis's Triton-2 study in prostate cancer. The analyst is "quite confident" that the company's PARP inhibitor rucaparib should produce response rates that are well above chemotherapy and anti-androgens, at least in third line BRCA positive patients. He views the Triton-2 update as an important event for Clovis and believes "promising results could represent a step towards restoring more favorable sentiment." A response rate of at least 30% is the lower bar for share appreciation, Kasimov tells investors in a research note. He keeps an Overweight rating on Clovis.
09/24/18
LEER
09/24/18
INITIATION
Target $30
LEER
Market Perform
Clovis initiated with a Market Perform at Leerink
Leerink analyst Andrew Berens started Clovis Oncology with a Market Perform rating and $30 price target.

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WOLWF

Woolworths Group

$0.00

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LLESY

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EFSC

Enterprise Financial

$41.41

0.99 (2.45%)

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FB

Facebook

$150.01

1.77 (1.19%)

16:36
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FB

Facebook

$150.01

1.77 (1.19%)

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ENB

Enbridge

$36.10

0.425 (1.19%)

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LIN

Linde plc

$160.76

3.48 (2.21%)

16:25
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16:25
Periodicals
Linde Plc to launch $6B share buyback scheme, Reuters says »

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HENKY

Henkel

$0.00

(0.00%)

16:01
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16:01
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CAG

Conagra Brands

$21.58

0.34 (1.60%)

14:06
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  • 22

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General news
IMF trimmed global growth amid "no-deal" Brexit and trade war concerns »

IMF trimmed global growth…

UQM

UQM Technologies

$1.10

0.05 (4.76%)

13:05
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UQM Technologies acquired by Danfoss Power Solutions for $1.71 per share »

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SNY

Sanofi

$41.50

-0.54 (-1.28%)

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RTN

Raytheon

$165.11

2.285 (1.40%)

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IBCP

Independent Bank

$22.80

-0.11 (-0.48%)

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FX Update: The dollar majors have been directionally challenged »

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EDIT

Editas Medicine

$26.16

-0.01 (-0.04%)

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GOOG

Alphabet

$1,098.25

6.96 (0.64%)

, GOOGL

Alphabet Class A

$1,106.92

7.52 (0.68%)

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GOOG

Alphabet

$1,098.25

6.96 (0.64%)

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Alphabet Class A

$1,106.92

7.52 (0.68%)

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LAD

Lithia Motors

$87.13

1.57 (1.84%)

10:25
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Conference/Events
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CYDY

CytoDyn

$0.00

(0.00%)

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ABT

Abbott

$71.43

0.9 (1.28%)

09:50
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SFUN

Fang Holdings

$1.88

-0.01 (-0.53%)

09:48
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TS

Tenaris

$24.32

0.64 (2.70%)

09:45
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PAAS

Pan American Silver

$14.17

-0.31 (-2.14%)

09:42
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CRWS

Crown Crafts

$5.68

(0.00%)

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AL

Air Lease

$37.50

0.6 (1.63%)

, BA

Boeing

$364.79

5.52 (1.54%)

09:36
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AL

Air Lease

$37.50

0.6 (1.63%)

BA

Boeing

$364.79

5.52 (1.54%)

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