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EPZM

Epizyme

$9.66

-0.78 (-7.47%)

16:01
10/02/18
10/02
16:01
10/02/18
16:01

Epizyme files to sell common stock, no amount given

Jefferies is acting as sole book-running manager for the proposed offering.

  • 02

    Oct

EPZM Epizyme
$9.66

-0.78 (-7.47%)

09/07/18
MSCO
09/07/18
INITIATION
Target $12
MSCO
Equal Weight
Epizyme resumed with an Equal Weight at Morgan Stanley
Morgan Stanley analyst David Lebowitz resumed coverage of Epizyme with an Equal Weight rating and $12 price target, recommending investors stay on the sidelines despite tazemetostat's potential as the partial clinical hold imposed in April by the FDA clouds the timing and increases the level of risk for the drug.
09/21/18
SBSH
09/21/18
NO CHANGE
SBSH
Buy
Citi opens 30 day catalyst watch for Epizyme
Citi analyst Robyn Karnauskas opened a 30 day catalyst watch for Epizyme in anticipation of an FDA decision on the partial hold on Tazemetostat. In the best case scenario, the analyst expects the partial hold to be lifted at the end of the 30 day period without any further delay. She notes that We note that Tazemetostat has been investigated in multiple indications, administered to 750 patients, and shown an overall positive safety profile with only a single case of secondary lymphoma. The analyst keeps a Buy rating on Epizyme.
09/24/18
LEER
09/24/18
INITIATION
Target $11
LEER
Market Perform
Epizyme initiated with a Market Perform at Leerink
Leerink analyst Andrew Berens started Epizyme with a Market Perform rating and $11 price target.
09/25/18
RHCO
09/25/18
NO CHANGE
Target $25
RHCO
Buy
Epizyme price target raised to $25 from $20 at SunTrust
SunTrust analyst Peter Lawson raised his price target on Epizyme to $25 and kept his Buy rating, citing the FDA decision for a partial clinical hold lift on tazemetostat enrollment. The analyst notes that the company has not announced any substantial changes to the trial design or patient population, but rather will increase patient monitoring after updating its exclusion criteria for new patient enrollment. Lawson contends that the New Drug Application submission for tazemetostat in the treatment of epithelioid sarcoma expected in the first half of 2019 remains on track.

TODAY'S FREE FLY STORIES

MRK

Merck

$72.34

0.12 (0.17%)

, AZN

AstraZeneca

$39.21

0.25 (0.64%)

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MRK

Merck

$72.34

0.12 (0.17%)

AZN

AstraZeneca

$39.21

0.25 (0.64%)

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VAR

Varian Medical

$104.25

-1.575 (-1.49%)

16:31
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Varian unveils new Bravos afterloader system for brachytherapy treatments »

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  • 23

    Oct

NTGN

Neon Therapeutics

$8.88

0.56 (6.73%)

14:30
10/21/18
10/21
14:30
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14:30
Conference/Events
Neon Therapeutics management to meet with Morgan Stanley »

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GTHX

G1 Therapeutics

$46.88

-0.07 (-0.15%)

14:13
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G1 presents additional data from randomized Phase 2 trial in first-line SCLC »

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  • 27

    Nov

NCNA

NuCana

$18.90

1.9 (11.18%)

14:09
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NuCana reports additional data on NUC-1031 in advanced biliary tract cancer »

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  • 21

    Oct

LPTX

Leap Therapeutics

$6.44

-0.17 (-2.57%)

, MRK

Merck

$72.34

0.12 (0.17%)

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Leap Therapeutics presents esophagogastric cancer data »

Leap Therapeutics (LPTX)…

LPTX

Leap Therapeutics

$6.44

-0.17 (-2.57%)

MRK

Merck

$72.34

0.12 (0.17%)

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INCY

Incyte

$66.09

1.66 (2.58%)

14:02
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Incyte announces positive interim data from Phase 2 trial of Pemigatinib »

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  • 22

    Oct

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    Oct

LOXO

Loxo Oncology

$160.01

-7.58 (-4.52%)

, BAYRY

Bayer

$0.00

(0.00%)

13:58
10/21/18
10/21
13:58
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13:58
Hot Stocks
Loxo's larotrectinib delivers 81% ORR in expanded dataset of 109 TRK fusion cancer »

Bayer (BAYRY) and Loxo…

LOXO

Loxo Oncology

$160.01

-7.58 (-4.52%)

BAYRY

Bayer

$0.00

(0.00%)

03/08/13
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  • 21

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    Nov

LOXO

Loxo Oncology

$160.01

-7.58 (-4.52%)

, BAYRY

Bayer

$0.00

(0.00%)

13:53
10/21/18
10/21
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13:53
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Loxo announces larotrectinib clinical update in patients with TRK fusion cancers »

Loxo Oncology (LOXO)…

LOXO

Loxo Oncology

$160.01

-7.58 (-4.52%)

BAYRY

Bayer

$0.00

(0.00%)

03/08/13
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  • 21

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    Nov

MRTX

Mirati Therapeutics

$40.04

-1.82 (-4.35%)

13:45
10/21/18
10/21
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13:45
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Mirati announces updated data from ongoing trial of single agent sitravatinib »

Mirati Therapeutics…

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  • 21

    Oct

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    Oct

RHHBY

Roche

$0.00

(0.00%)

13:39
10/21/18
10/21
13:39
10/21/18
13:39
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Entrectinib shrank tumors in people with NTRK fusion-positive solid tumors »

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  • 21

    Oct

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    Dec

GILD

Gilead

$73.27

-0.9 (-1.21%)

, GLPG

Galapagos NV

$107.66

2.29 (2.17%)

13:34
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10/21
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13:34
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Gilead, Galapagos NV announced data from Phase 3 FINCH2 trial of filgotinib »

Gilead Sciences (GILD)…

GILD

Gilead

$73.27

-0.9 (-1.21%)

GLPG

Galapagos NV

$107.66

2.29 (2.17%)

03/08/13
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  • 24

    Oct

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    Nov

BLRX

BioLineRx

$0.98

-0.22 (-18.33%)

, MRK

Merck

$72.34

0.12 (0.17%)

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BioLineRx discloses additional data from Phase 2a COMBAT/KEYNOTE-202 study »

BioLineRx (BLRX)…

BLRX

BioLineRx

$0.98

-0.22 (-18.33%)

MRK

Merck

$72.34

0.12 (0.17%)

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  • 23

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ADAP

Adaptimmune

$10.79

-0.09 (-0.83%)

13:22
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Adaptimmune presents updated data from ongoing MAGE-A10, MAGE-A4 studies »

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RHHBY

Roche

$0.00

(0.00%)

13:02
10/21/18
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Genentech's Tecentriq, Abraxane combo demonstrates positive Phase III results »

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  • 21

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PFE

Pfizer

$44.50

0.48 (1.09%)

12:56
10/21/18
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Pfizer presents overall survival data from PALOMA-3 trial of Ibrance »

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  • 22

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    Nov

MRK

Merck

$72.34

0.12 (0.17%)

12:52
10/21/18
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Merck presents early data for STING agonist in advanced solid tumors/lymphomas »

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  • 23

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    Feb

DVAX

Dynavax

$10.90

-0.47 (-4.13%)

, MRK

Merck

$72.34

0.12 (0.17%)

12:47
10/21/18
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Dynavax's SD-101, Keytruda combo still shows 70% ORR in Advanced Melanoma »

Dynavax (DVAX) presented…

DVAX

Dynavax

$10.90

-0.47 (-4.13%)

MRK

Merck

$72.34

0.12 (0.17%)

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  • 23

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    Feb

EXEL

Exelixis

$16.27

-0.25 (-1.51%)

12:44
10/21/18
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Exelixis announces results from data analysis of CABOSUN, METEOR trials »

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  • 21

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    Jan

AGEN

Agenus

$1.97

-0.025 (-1.26%)

12:39
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Agenus presents clinical data on PD-1, CTLA-4 at ESMO 2018 »

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  • 07

    Nov

OMED

OncoMed

$2.47

-0.17 (-6.44%)

12:37
10/21/18
10/21
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OncoMed announces interim phase 1b results for Navicixizumab, Paclitaxel combo »

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IMGN

ImmunoGen

$7.44

-0.355 (-4.56%)

, MRK

Merck

$72.34

0.12 (0.17%)

12:34
10/21/18
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12:34
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ImmunoGen presents initial data from FORWARD II expansion cohort »

ImmunoGen (IMGN)…

IMGN

ImmunoGen

$7.44

-0.355 (-4.56%)

MRK

Merck

$72.34

0.12 (0.17%)

03/08/13
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  • 23

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  • 02

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    Feb

BMY

Bristol-Myers

$54.31

-1.7 (-3.04%)

12:30
10/21/18
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Opdivo, Yervoy combo shows promising results in advanced form of bladder cancer »

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  • 22

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    Oct

  • 07

    Nov

MRK

Merck

$72.34

0.12 (0.17%)

12:26
10/21/18
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  • 23

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    Feb

TSRO

Tesaro

$41.81

-1.19 (-2.77%)

12:18
10/21/18
10/21
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  • 01

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