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CNAT

Conatus

$5.32

-0.09 (-1.66%)

16:08
10/02/18
10/02
16:08
10/02/18
16:08

Conatus announces three accepted abstracts for AASLD annual meeting

Conatus Pharmaceuticals announced that two abstracts - one addressing clinical results with the company's pan-caspase inhibitor, emricasan, and one addressing preclinical results with the company's pan-caspase inhibitor, IDN-7314 - have been accepted for oral presentations; and one abstract addressing preclinical results with emricasan has been accepted for a poster presentation at The Liver Meeting, the annual meeting of the American Association for the Study of Liver Diseases, AASLD, in San Francisco November 9-13. Accepted abstracts were published yesterday on the Hepatology website. Abstracts accepted for oral presentations included: "Multicenter, double-blind, randomized trial of emricasan in subjects post liver transplantation with recurrent hepatitis C virus and liver fibrosis or cirrhosis despite achieving sustained virologic response and "Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis."and abstracts accepted for posters included: "Molecular mechanisms underlying the effects of emricasan in portal hypertension and chronic liver disease: the hepato-sinusoidal cross-talk matters." Abstract #25 is an AASLD Foundation Abstract Award Recipient and was accepted for presentation in the Presidential Plenary Session on Translational Science and Genomics

  • 17

    Oct

CNAT Conatus
$5.32

-0.09 (-1.66%)

03/02/18
OPCO
03/02/18
INITIATION
Target $16
OPCO
Outperform
Conatus initiated with an Outperform at Oppenheimer
Oppenheimer analyst Jay Olson initiated Conatus (CNAT) with an Outperform rating and $16 price target based on his view that significant value for shareholders, physicians and patients can be unlocked by the company's "unique" approach to liver disease. In a research note to investors, Olson said he sees emricasan as well positioned to potentially demonstrate efficacy in a broad range of liver diseases, including NASH, adding that the program is viewed as "partially de-risked" through its partnership with Novartis (NVS).
03/02/18
03/02/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Home Depot (HD), Lowe's (LOW), Tempur Sealy (TPX), Mohawk (MHK), Lumber Liquidators (LL) and Michaels (MIK) initiated with a Hold at Loop Capital. The firm also started Fortune Brands (FBHS) and Wayfair (W) with a Buy. 2. Aflac (AFL), Lincoln National (LNC), Brighthouse Financial (BHF), MetLife (MET) Unum (UNM), Principal Financial (PFG) and Reinsurance Group (RGA) initiated with a Neutral at UBS. The firm also initiated Voya (VOYA) and FGL Holdings (FG) with a Buy and Torchmark (TMK) and American Equity (AEL) with a Sell. 3. HP Enterprise (HPE) initiated with a Neutral at JPMorgan. 4. Caterpillar (CAT), Deere (DE), United Rentals (URI) and Wabco (WBC) initiated with an Overweight, Oshkosh (OSK), Terex (TEX), Cummins (CMI), CNH Industrial (CNHI) and REV Group (REVG) initiated with an Equal Weight and Paccar (PCAR) and Agco (AGCO) initiated with an Underweight at Morgan Stanley. 5. Conatus (CNAT) initiated with an Outperform at Oppenheimer. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
04/05/18
HCWC
04/05/18
NO CHANGE
Target $15
HCWC
Buy
Conatus data encouraging despite endpoint miss, says H.C. Wainwright
H.C. Wainwright analyst Ed Arce says that while the Phase 2b POLT-HCV-SVR clinical trial of emricasan missed the primary endpoint, the data are encouraging. The analyst lowered his price target for Conatus Pharmaceuticals to $15 from $17 and affirms a Buy rating on the shares. He views the after-hours selloff last night as an overreaction.
04/05/18
RHCO
04/05/18
NO CHANGE
Target $20
RHCO
Buy
Conatus price target lowered to $20 from $26 at SunTrust
SunTrust analyst John Boris lowered his price target on Conatus to $20, citing the company's failed phase 2b POLT-HCV-SVR study evaluating post-orthotopic liver transplant recipients that achieved sustained virological response. Boris notes however that although Emricasan did not generate a 15% absolute difference in response rate relative to placebo, the trial results still show "anti-fibrotic activity by histology, with biopsy-based responses after Year 1 & 2". The analyst keeps his Buy rating on Conatus, adding that POLT-HCV-SVR remains important for the company in providing optionality to expand clinical pathway to a much broader pre-transplant patient population.

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