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ADMS

Adamas Pharmaceuticals

$19.95

0.36 (1.84%)

09:14
10/04/18
10/04
09:14
10/04/18
09:14

Adamas Pharmaceuticals publishes Phase 3 Gocovri data

Adamas Pharmaceuticals announced that pooled Phase 3 data of Gocovri extended release capsules were published online in Parkinsonism and Related Disorders. Results from pooled Phase 3 ADS-5102 clinical trials, concluded that dyskinesias in people with Parkinson's disease can impact a patient's activities of daily living, or ADLs, across multiple tasks and that treatment with Gocovri can help ameliorate the impairment. Gocovri is the first and only medicine approved by the FDA for the treatment of dyskinesia in patients with Parkinson's disease receiving levodopa-based therapy, with or without concomitant dopaminergic medications. It is also the only drug approved by the FDA to treat dyskinesia in people with Parkinson's disease on levodopa therapy, as well as demonstrate a secondary benefit in reducing off time in that population. In the pooled Phase 3 analysis, most adverse reactions were of mild to moderate intensity, and the most common adverse reactions were hallucination, dizziness, dry mouth, peripheral edema, constipation, falls, and orthostatic hypotension.

ADMS Adamas Pharmaceuticals
$19.95

0.36 (1.84%)

09/17/18
HCWC
09/17/18
NO CHANGE
Target $45
HCWC
Buy
Adamas COO departure unlikely to be disruptive, says H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju believes the departure of Chief Operating Officer Richard King is unlikely to be disruptive for Adamas Pharmaceuticals. The analyst continues to anticipate further traction for Adamas's sole marketed product, Gocovri, in the coming months. He reiterates a Buy rating on the shares with a $45 price target.
09/17/18
MZHO
09/17/18
NO CHANGE
Target $75
MZHO
Buy
Adamas COO departure does not signal red flags, says Mizuho
Mizuho analyst Irina Koffler expects pressure on shares of Adamas Pharmaceuticals (ADMS) from what she sees as two unrelated events: competitor Osmotica filing for an initial public offering and the resignation of COO Richard King for personal reasons. The IPO was already anticipated by investors, and the executive departure doesn't signal any red flags, Koffler tells investors in a research note. She reiterates a Buy rating on Adamas with a $75 price target.
08/07/18
HCWC
08/07/18
NO CHANGE
Target $45
HCWC
Buy
Adamas patient deaths 'may not be cause for alarm,' says H.C. Wainwright
News emerged yesterday that three deaths had occurred during the month of June among patients treated with Adamas Pharmaceuticals' Gocovri, according to data captured by the FDA's Adverse Events Reporting System database, H.C. Wainwright analyst Raghuram Selvaraju tells investors in a research note. The analyst says that while he can't rule out the possibility that these deaths were due to the drug, he notes that the FDA itself acknowledges the fact that, while the FAERS database is aimed at collecting adverse event reporting on as many drugs as possible, the occurrence of adverse events in patients taking a particular drug does not mean that the drug actually caused the adverse event in question. Deaths among Gocovri patients "may not be cause for alarm," the analyst contends. Selvaraju believes investors are perhaps "being too quick to draw a link" between adverse event reporting on Nuplazid and patient deaths on Gocovri. The analyst reiterates a Buy rating on Adamas Pharmaceuticals with a $45 price target.
07/16/18
HCWC
07/16/18
INITIATION
Target $45
HCWC
Buy
Adamas Pharmaceuticals initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju started Adamas Pharmaceuticals with a Buy rating and $45 price target. The analyst believes the company could reach cash flow-positive status in early to mid-2020 and finds the launch parameters of Gocovri encouraging.

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