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BMY

Bristol-Myers

$57.50

-3.28 (-5.40%)

07:01
10/12/18
10/12
07:01
10/12/18
07:01

Bristol-Myers reports Phase 3 CheckMate-331 study does not meet primary endpoint

Bristol-Myers Squibb announced topline results from the Phase 3 CheckMate -331 study evaluating Opdivo versus the current standard of care, topotecan or amrubicin, in patients with small cell lung cancer who relapsed following platinum-based chemotherapy. The study did not meet its primary endpoint of overall survival with Opdivo versus chemotherapy. The safety profile of Opdivo in this trial was consistent with that observed in previously reported monotherapy studies involving patients with SCLC. Sabine Maier, M.D., development lead, thoracic cancers, Bristol-Myers Squibb, commented, "Small cell lung cancer is a highly aggressive disease in which significant unmet need remains. We are focused on researching innovative oncology therapies to improve outcomes for patients with lung cancer. We thank the patients, their families, and the physicians involved in the CheckMate -331 study."

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BMY Bristol-Myers
$57.50

-3.28 (-5.40%)

10/08/18
GUGG
10/08/18
INITIATION
Target $70
GUGG
Neutral
Bristol-Myers initiated with a Neutral at Guggenheim
Guggenheim analyst Seamus Fernandez started Bristol-Myers with a Neutral rating and $70 price target, contending that near-term Opdivo catalysts are largely in the stock. He sees the risk-reward as being balanced ahead of several trial read outs in 2019 from Bristol and its competitors, Fernandez added.
09/12/18
FBCO
09/12/18
NO CHANGE
FBCO
Neutral
Bristol-Myers' TYK2 efficacy looks better than Otezla, says Credit Suisse
After Bristol-Myers (BMY) presented Phase 2 data for its oral TYK2 inhibitor, BMS-986165, in moderate-to-severe psoriasis at the EAVD meeting, Credit Suisse analyst Vamil Divan said he believes the "robust" data are very encouraging for the ongoing Phase 3 studies. BMS-986165 achieved PASI 75 response rates that are better than what was demonstrated by Celgene's (CELG) Otezla and the safety profile "appears reasonable," Divan tells investors. While BMS-986165 could be highly competitive clinically against other oral treatments, the crowded psoriasis market remains a tough one for new products, added the analyst, who keeps a Neutral rating on Bristol-Myers shares.
09/06/18
MSCO
09/06/18
NO CHANGE
Target $63
MSCO
Equal Weight
Bristol-Myers' TYK2 inhibitor may be underappreciated asset, says Morgan Stanley
Morgan Stanley analyst David Risinger said that Phase 2 data on Bristol-Myers' oral TYK2 inhibitor BMS-986165 will be presented at the EADV meeting on Wednesday September 12, adding that it could be an underappreciated asset if it offers better efficacy than other oral drugs and is safer. To his knowledge, no JAK inhibitors are currently being developed for psoriasis, Risinger noted. The analyst, who said 986165 "theoretically has blockbuster potential," maintains an Equal Weight rating on Bristol shares as further Opdivo lung newsflow is awaited.
08/08/18
08/08/18
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Dean Foods (DF) upgraded to Hold from Sell at Deutsche Bank. 2. Plantronics (PLT) upgraded to Buy from Neutral at Sidoti with the firm citing attractive valuation. 3. CarGurus (CARG) upgraded to Outperform from Market Perform at JMP Securities and to Outperform from Sector Perform at RBC Capital. 4. Bristol-Myers (BMY) upgraded to Neutral from Underweight at Atlantic Equities. 5. Floor & Decor (FND) upgraded to Buy from Hold at Loop Capital with analyst Anthony Chukumba saying the company continues to post the "best relative performance in the flooring retailing industry." This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

PYPL

PayPal

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TRV

Travelers

$125.08

-1.39 (-1.10%)

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F

Ford

$8.51

-0.255 (-2.91%)

06:41
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VIVHY

Vivendi

$0.00

(0.00%)

, TI

Telecom Italia

$5.89

-0.05 (-0.84%)

06:41
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06:41
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06:41
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Vivendi denies wanting four more members on Telecom Italia's board, Reuters says »

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VIVHY

Vivendi

$0.00

(0.00%)

TI

Telecom Italia

$5.89

-0.05 (-0.84%)

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FB

Facebook

$154.95

-4.51 (-2.83%)

06:39
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06:39
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06:39
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Facebook's election 'war room' ready for midterms, Business Insider says »

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ROKU

Roku

$56.99

-3.92 (-6.44%)

06:38
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10/19
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AEO

American Eagle

$20.94

-0.54 (-2.51%)

06:38
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06:38
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HON

Honeywell

$155.22

-2.73 (-1.73%)

06:37
10/19/18
10/19
06:37
10/19/18
06:37
Earnings
Honeywell lowers FY18 adj. EPS view to $7.95-$8.00 from $8.10-$8.20 »

Consensus $8.15. Lowers…

03/08/13
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  • 19

    Oct

SYNH

Syneos Health

$45.94

-0.65 (-1.40%)

06:37
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06:37
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AMZN

Amazon.com

$1,771.45

-61.36 (-3.35%)

06:36
10/19/18
10/19
06:36
10/19/18
06:36
Periodicals
Amazon revisits some cities as HQ2 decision looms, WSJ reports »

Amazon executives have…

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  • 25

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MUR

Murphy Oil

$34.63

-0.43 (-1.23%)

, PBR

Petrobras

$15.33

-0.73 (-4.55%)

06:35
10/19/18
10/19
06:35
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06:35
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Murphy Oil, Petrobras rating change  »

Murphy Oil upgraded to…

MUR

Murphy Oil

$34.63

-0.43 (-1.23%)

PBR

Petrobras

$15.33

-0.73 (-4.55%)

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  • 08

    Nov

SYF

Synchrony

$29.63

-0.45 (-1.50%)

06:34
10/19/18
10/19
06:34
10/19/18
06:34
Hot Stocks
Synchrony CEO says 'we generated strong results this quarter' »

"We generated strong…

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CFG

Citizens Financial

$34.92

-0.96 (-2.68%)

06:33
10/19/18
10/19
06:33
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06:33
Earnings
Citizens Financial reports Q3 EPS 91c, consensus 90c »

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  • 19

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MINI

Mobile Mini

$43.37

0.48 (1.12%)

06:33
10/19/18
10/19
06:33
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06:33
Hot Stocks
Mobile Mini CEO says the pipeline in North America looks healthy »

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  • 19

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MRO

Marathon Oil

$20.55

-0.33 (-1.58%)

06:33
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  • 08

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HON

Honeywell

$155.22

-2.73 (-1.73%)

06:32
10/19/18
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06:32
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06:32
Earnings
Honeywell reports Q3 adj. EPS $2.03, consensus $1.99 »

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MINI

Mobile Mini

$43.37

0.48 (1.12%)

06:32
10/19/18
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06:32
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06:32
Earnings
Mobile Mini reports Q3 adjusted EPS 42c, consensus 41c »

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  • 19

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WTFC

Wintrust Financial

$79.79

-4.06 (-4.84%)

06:31
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BX

Blackstone

$35.27

-0.79 (-2.19%)

06:31
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06:31
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Blackstone waves off concerns over Saudi funding, Reuters reports »

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REPYY

Repsol

$0.00

(0.00%)

06:31
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SYF

Synchrony

$29.63

-0.45 (-1.50%)

06:31
10/19/18
10/19
06:31
10/19/18
06:31
Earnings
Synchrony reports Q3 EPS 91c, consensus 80c »

Return on assets was 2.7%…

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SMCI

Super Micro Computer

$0.00

(0.00%)

06:31
10/19/18
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06:31
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06:31
Periodicals
Super Micro Computer says no evidence for Chinese hack, Bloomberg reports »

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  • 29

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AA

Alcoa

$38.85

2.14 (5.83%)

, CENX

Century Aluminum

$9.91

-0.23 (-2.27%)

06:25
10/19/18
10/19
06:25
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06:25
Periodicals
United States wants WTO panel to resolve matals tariff dispute, Reuters says »

The United States wants a…

AA

Alcoa

$38.85

2.14 (5.83%)

CENX

Century Aluminum

$9.91

-0.23 (-2.27%)

X

U.S. Steel

$27.91

-0.27 (-0.96%)

NUE

Nucor

$58.26

-0.85 (-1.44%)

03/08/13
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CPB

Campbell Soup

$36.67

0.35 (0.96%)

, TPRE

Third Point Reinsurance

$11.40

-0.3 (-2.56%)

06:24
10/19/18
10/19
06:24
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06:24
Periodicals
Campbell Soup CEO sees no room for concessions to Third Point, Reuters reports »

Campbell Soup (CPB)…

CPB

Campbell Soup

$36.67

0.35 (0.96%)

TPRE

Third Point Reinsurance

$11.40

-0.3 (-2.56%)

03/08/13
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PYPL

PayPal

$77.50

-2.61 (-3.26%)

06:22
10/19/18
10/19
06:22
10/19/18
06:22
Recommendations
PayPal analyst commentary  »

Loop Capital concerned…

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