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ALNY

Alnylam

$81.00

1.51 (1.90%)

10:09
10/12/18
10/12
10:09
10/12/18
10:09

Silence reports 'favorable' outcome of U.S. PTAB decision against Alnylam

Silence Therapeutics reported what it called a "favorable" outcome of a decision by the U.S. Patent Trial & Appeal Board, or PTAB, against Alnylam. In the U.S., Alnylam filed a total of five Post Grant Review petitions against newly-issued Silence patents challenging the validity of the issued claims. In the first decision on Alnylam's petitions, the PTAB denied institution of post-grant review, finding that Alnylam had not met its initial burden of showing that the claims are invalid, Silence stated. "The PTAB's decision not to institute review provides yet another vindication of the strength of Silence's worldwide patent portfolio. Decisions on the remaining petitions are expected over the next several months," the company said.

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ALNY Alnylam
$81.00

1.51 (1.90%)

10/01/18
CANT
10/01/18
INITIATION
Target $135
CANT
Overweight
Alnylam initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Alethia Young started Alnylam Pharmaceuticals with an Overweight rating and $135 price target.
10/07/18
PIPR
10/07/18
NO CHANGE
Target $160
PIPR
Overweight
Alnylam's Onpattro highly efficacious, safer than competitor, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff notes that Ionis Pharmaceuticals (IONS) announced FDA approval of TEGSEDI for treatment of hATTR polyneuropathy. The analyst also points out that the label includes a Black Box warning for thrombocytopenia and glomerulonephritis requiring every 2-week monitoring, and will be marketed by Ionis subsidiary Akcea (AKCA) with a Risk Evaluation and Mitigation Strategy. TEGSEDI is administered subcutaneously every week versus Alnylam's (ANLY) ONPATTRO intravenously every 3 weeks with steroids, he adds. Tenthoff believes that ONPATTRO appears safer and highly efficacious, and should win out. The analyst reiterates an Overweight rating and $160 price target on Alnylam shares.
10/08/18
CANT
10/08/18
INITIATION
Target $135
CANT
Overweight
Cantor reiterates Overweight on Alnylam after Akcea, Ionis win approval
Cantor Fitzgerald analyst Alethia Young reiterates an Overweight rating on Alnylam Pharmaceuticals (ALNY) with a $135 price target after the FDA approved Tegsedi, to be marketed by Akcea Therapeutics (AKCA). The analyst says that while the approval introduces another competitor to the market, she still expects Alnylam's Onpattroto be able to take significant share in the polyneuropathy hATTR market. Young thinks the Tegsedi label is more onerous and currently models a 60% peak share to Alnylam, a 25% share to Tegsedi and 15% to future competition.
10/08/18
GSCO
10/08/18
NO CHANGE
Target $36
GSCO
Sell
Ionis' Tegsedi to face commercial headwinds, says Goldman Sachs
After the FDA approved Ionis (IONS) and affiliate Akcea Therapeutics' (AKCA) Tegsedi for adult polyneuropathy of hereditary transthyretin-mediated amyloidosis, but with a black box warning, Goldman Sachs analyst Salveen Richter said he believes the drug faces commercial headwinds. He cites the underlying safety profile and requirement for consistent monitoring as well as the recent launch of Alnylam's (ALNY) Onpattro and expected launch of Pfizer's (PFE) tafamidis in the first half of 2019. Richter keeps a Sell rating on Ionis shares with a price target of $36.

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BAYRY

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APHA

Aphria

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LOGI

Logitech

$33.69

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WBA

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$71.59

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SMBC

Southern Missouri Bancorp

$32.22

-0.29 (-0.89%)

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Z

Zillow

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VIA

Viacom

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GOOG

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VIA

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VIAB

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AZZ

AZZ Inc.

$45.09

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TSLA

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NCOM

National Commerce

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IBM

IBM

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UAL

United Continental

$83.34

-2.27 (-2.65%)

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  • 04

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AQMS

Aqua Metals

$2.16

0.07 (3.35%)

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DKS

Dick's Sporting

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  • 03

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BA

Boeing

$357.91

-6.88 (-1.89%)

, LLL

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LLL

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LDOS

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NOC

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$264.70

-2.84 (-1.06%)

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ATXI

Avenue Therapeutics

$6.35

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UCFC

United Community Financial

$9.14

(0.00%)

17:44
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Earnings
United Community Financial reports Q4 EPS 19c, consensus 20c »

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  • 23

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FMBI

First Midwest

$21.88

-0.21 (-0.95%)

17:39
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Earnings
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