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ALNY

Alnylam

$81.00

1.51 (1.90%)

10:09
10/12/18
10/12
10:09
10/12/18
10:09

Silence reports 'favorable' outcome of U.S. PTAB decision against Alnylam

Silence Therapeutics reported what it called a "favorable" outcome of a decision by the U.S. Patent Trial & Appeal Board, or PTAB, against Alnylam. In the U.S., Alnylam filed a total of five Post Grant Review petitions against newly-issued Silence patents challenging the validity of the issued claims. In the first decision on Alnylam's petitions, the PTAB denied institution of post-grant review, finding that Alnylam had not met its initial burden of showing that the claims are invalid, Silence stated. "The PTAB's decision not to institute review provides yet another vindication of the strength of Silence's worldwide patent portfolio. Decisions on the remaining petitions are expected over the next several months," the company said.

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    Nov

ALNY Alnylam
$81.00

1.51 (1.90%)

10/01/18
CANT
10/01/18
INITIATION
Target $135
CANT
Overweight
Alnylam initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Alethia Young started Alnylam Pharmaceuticals with an Overweight rating and $135 price target.
10/07/18
PIPR
10/07/18
NO CHANGE
Target $160
PIPR
Overweight
Alnylam's Onpattro highly efficacious, safer than competitor, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff notes that Ionis Pharmaceuticals (IONS) announced FDA approval of TEGSEDI for treatment of hATTR polyneuropathy. The analyst also points out that the label includes a Black Box warning for thrombocytopenia and glomerulonephritis requiring every 2-week monitoring, and will be marketed by Ionis subsidiary Akcea (AKCA) with a Risk Evaluation and Mitigation Strategy. TEGSEDI is administered subcutaneously every week versus Alnylam's (ANLY) ONPATTRO intravenously every 3 weeks with steroids, he adds. Tenthoff believes that ONPATTRO appears safer and highly efficacious, and should win out. The analyst reiterates an Overweight rating and $160 price target on Alnylam shares.
10/08/18
CANT
10/08/18
INITIATION
Target $135
CANT
Overweight
Cantor reiterates Overweight on Alnylam after Akcea, Ionis win approval
Cantor Fitzgerald analyst Alethia Young reiterates an Overweight rating on Alnylam Pharmaceuticals (ALNY) with a $135 price target after the FDA approved Tegsedi, to be marketed by Akcea Therapeutics (AKCA). The analyst says that while the approval introduces another competitor to the market, she still expects Alnylam's Onpattroto be able to take significant share in the polyneuropathy hATTR market. Young thinks the Tegsedi label is more onerous and currently models a 60% peak share to Alnylam, a 25% share to Tegsedi and 15% to future competition.
10/08/18
GSCO
10/08/18
NO CHANGE
Target $36
GSCO
Sell
Ionis' Tegsedi to face commercial headwinds, says Goldman Sachs
After the FDA approved Ionis (IONS) and affiliate Akcea Therapeutics' (AKCA) Tegsedi for adult polyneuropathy of hereditary transthyretin-mediated amyloidosis, but with a black box warning, Goldman Sachs analyst Salveen Richter said he believes the drug faces commercial headwinds. He cites the underlying safety profile and requirement for consistent monitoring as well as the recent launch of Alnylam's (ALNY) Onpattro and expected launch of Pfizer's (PFE) tafamidis in the first half of 2019. Richter keeps a Sell rating on Ionis shares with a price target of $36.

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SIBN

SI-BONE

$0.00

(0.00%)

20:54
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Syndicate
SI-BONE 7.2M share IPO priced at $15.00 »

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AMX

America Movil, also tag AMOV

$15.77

0.38 (2.47%)

, AMOV

America Movil, also tag AMX

$15.03

(0.00%)

20:44
10/16/18
10/16
20:44
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20:44
Earnings
America Movil reports Q3 net income MXN18.96B vs. MXN2.52B last year »

Reports Q3 revenue…

AMX

America Movil, also tag AMOV

$15.77

0.38 (2.47%)

AMOV

America Movil, also tag AMX

$15.03

(0.00%)

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ABT

Abbott

$70.94

2.22 (3.23%)

, USB

U.S. Bancorp

$50.97

0.44 (0.87%)

20:25
10/16/18
10/16
20:25
10/16/18
20:25
Earnings
Notable companies reporting before tomorrow's open »

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ABT

Abbott

$70.94

2.22 (3.23%)

USB

U.S. Bancorp

$50.97

0.44 (0.87%)

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ADTN

Adtran

$18.15

1.08 (6.33%)

20:24
10/16/18
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20:24
Earnings
Adtran reports Q3 adjusted EPS 21c, consensus 4c »

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WAFD

Washington Federal

$29.75

0.45 (1.54%)

20:02
10/16/18
10/16
20:02
10/16/18
20:02
Earnings
Washington Federal reports Q4 EPS 62c, consensus 62c »

Reports Q4 NII $124.8M…

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  • 07

    Nov

UNH

UnitedHealth

$272.24

12.44 (4.79%)

19:30
10/16/18
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19:30
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19:30
Recommendations
UnitedHealth analyst commentary at Piper Jaffray »

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  • 16

    Oct

CDAY

Ceridian

$38.44

1.38 (3.72%)

19:25
10/16/18
10/16
19:25
10/16/18
19:25
Conference/Events
Ceridian to hold a conference »

INSIGHTS 2018 will be…

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  • 16

    Oct

HMC

Honda

$27.70

0.65 (2.40%)

19:07
10/16/18
10/16
19:07
10/16/18
19:07
Periodicals
Honda Aircraft sees higher light jet deliveries next year, Reuters says »

Honda Aircraft co-CEO…

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  • 24

    Oct

VALE

Vale

$15.50

0.045 (0.29%)

18:59
10/16/18
10/16
18:59
10/16/18
18:59
Periodicals
Vale plans to use cash flow cautiously going forward, Reuters says »

Vale said it intends to…

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VICR

Vicor Corporation

$38.35

1.42 (3.85%)

, NFLX

Netflix

$346.40

13.29 (3.99%)

18:55
10/16/18
10/16
18:55
10/16/18
18:55
Hot Stocks
Fly Intel: After Hours Movers »

UP AFTER EARNINGS: Vicor…

VICR

Vicor Corporation

$38.35

1.42 (3.85%)

NFLX

Netflix

$346.40

13.29 (3.99%)

LRCX

Lam Research

$145.33

2.72 (1.91%)

AMAT

Applied Materials

$34.76

1.33 (3.98%)

UAL

United Continental

$83.51

2.17 (2.67%)

FULT

Fulton Financial

$16.39

0.29 (1.80%)

CSX

CSX

$72.15

1.29 (1.82%)

CREE

Cree

$37.56

2.53 (7.22%)

ROKU

Roku

$63.67

1.97 (3.19%)

IBM

IBM

$145.02

3.9 (2.76%)

UFPI

Universal Forest

$34.08

1.27 (3.87%)

SONC

Sonic

$43.27

-0.03 (-0.07%)

EIGR

Eiger BioPharmaceuticals

$10.88

0.63 (6.15%)

SBH

Sally Beauty

$18.91

0.42 (2.27%)

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NFLX

Netflix

$346.40

13.29 (3.99%)

18:38
10/16/18
10/16
18:38
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18:38
Hot Stocks
Netflix says it has a 'long, long runway' in India »

Chief Product Officer…

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CBL

CBL & Associates

$3.52

0.085 (2.48%)

, SHLD

Sears

$0.40

0.09 (29.03%)

18:33
10/16/18
10/16
18:33
10/16/18
18:33
Hot Stocks
CBL Properties updates on redevelopment plan for Sears stores »

CBL Properties (CBL)…

CBL

CBL & Associates

$3.52

0.085 (2.48%)

SHLD

Sears

$0.40

0.09 (29.03%)

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  • 30

    Oct

VZ

Verizon

$53.68

0.08 (0.15%)

18:26
10/16/18
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18:26
Hot Stocks
Verizon says Bay, Gulf counties customers to be credited 3 months of service »

Verizon said that it is…

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  • 12

    Nov

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BMO

Bank of Montreal

$80.19

0.93 (1.17%)

18:09
10/16/18
10/16
18:09
10/16/18
18:09
Periodicals
Bank of Montreal names Wolford investment banking vice chair, Reuters says »

Bank of Montreal has…

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  • 24

    Oct

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SFTBF

SoftBank

$0.00

(0.00%)

18:02
10/16/18
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18:02
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18:02
Periodicals
SoftBank COO says 'anxiously' looking at Saudi Arabia situation, Reuters says »

SoftBank COO Marcelo…

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  • 16

    Oct

IBM

IBM

$145.02

3.9 (2.76%)

18:01
10/16/18
10/16
18:01
10/16/18
18:01
Hot Stocks
IBM sees growth in cloud overall »

Says incremental cash…

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CELC

Celcuity

$26.90

0.4 (1.51%)

, PBYI

Puma Biotechnology

$42.22

1.17 (2.85%)

17:57
10/16/18
10/16
17:57
10/16/18
17:57
Hot Stocks
Celcuity, Puma Biotechnology and West Cancer Center to conduct Phase 2 trial »

Celcuity (CELC) announced…

CELC

Celcuity

$26.90

0.4 (1.51%)

PBYI

Puma Biotechnology

$42.22

1.17 (2.85%)

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  • 19

    Oct

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DVN

Devon Energy

$37.08

0.98 (2.71%)

17:51
10/16/18
10/16
17:51
10/16/18
17:51
Recommendations
Devon Energy analyst commentary at MUFG »

Devon Energy price target…

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VIA

Viacom

$36.07

1.11 (3.18%)

, VIAB

Viacom

$32.83

1.05 (3.30%)

17:51
10/16/18
10/16
17:51
10/16/18
17:51
Periodicals
Viacom launches Nickelodeon Chinese Animation Development Project, Variety says »

According to Variety,…

VIA

Viacom

$36.07

1.11 (3.18%)

VIAB

Viacom

$32.83

1.05 (3.30%)

IQ

iQIYI

$25.91

-0.19 (-0.73%)

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  • 16

    Oct

BHP

BHP Billiton

$48.48

0.38 (0.79%)

17:38
10/16/18
10/16
17:38
10/16/18
17:38
Hot Stocks
BHP Billiton reports Q1 iron ore output 61.4M tons, up 10% from last year »

FY19 guidance for iron…

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UBER

Uber

$0.00

(0.00%)

17:37
10/16/18
10/16
17:37
10/16/18
17:37
Periodicals
Uber increases junk-bond offering to $2B, Bloomberg says »

Uber has boosted the size…

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IBM

IBM

$145.02

3.9 (2.76%)

17:32
10/16/18
10/16
17:32
10/16/18
17:32
Hot Stocks
IBM says growth was led by hybrid cloud, analytics and AI, digital and security »

Says remains on track…

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