Breaking News Instant updates and real-time market news.

EXEL

Exelixis

$16.27

-0.25 (-1.51%)

12:44
10/21/18
10/21
12:44
10/21/18
12:44

Exelixis announces results from data analysis of CABOSUN, METEOR trials

Exelixis announced results from two analyses evaluating the effect of PD-L1 expression or prior treatment with immune checkpoint inhibitors on the efficacy of cabozantinib in patients with advanced renal cell carcinoma. An analysis of data from the CABOSUN and METEOR trials demonstrated that cabozantinib improved clinical outcomes regardless of PD-L1 status in patients with advanced RCC, relative to sunitinib or everolimus, the respective comparator arms for each trial. Tumor tissue from 110 patients in the CABOSUN trial and 306 patients in the METEOR trial were evaluated to determine whether PD-L1 expression predicted outcomes or response to treatment. The findings showed that PD-L1 expression was associated with shorter median progression-free survival and overall survival in both METEOR and CABOSUN. Treatment with cabozantinib, however, improved PFS and OS compared with everolimus and sunitinib in both PD-L1 positive and PD-L1 negative patients. An additional analysis evaluating the activity of cabozantinib in 69 patients with advanced RCC who progressed on immune checkpoint inhibitors found that cabozantinib was active in patients previously treated with immune checkpoint inhibitors, either alone or in combination with anti-VEGF or other therapies. At a median follow-up of 12 months, objective response rate was 33%, disease control rate was 79 percent and the one-year overall survival rate was 53%.

  • 21

    Oct

  • 01

    Nov

  • 07

    Nov

  • 27

    Nov

  • 14

    Jan

EXEL Exelixis
$16.27

-0.25 (-1.51%)

10/08/18
PIPR
10/08/18
NO CHANGE
PIPR
Piper Jaffray optimistic on Exelixis' Cabometyx
Piper Jaffray analyst Edward Tenthoff reiterated an Overweight rating and $29 price target on Exelixis. The analyst noted that Exelixis initiated a Phase III trial of Cabometyx in radioiodine-refractory differentiated thyroid cancer, or DTC. He is looking for continued Cabometyx adoption in first and second-line renal cell carcinoma with sales of $572M this year, and sees Cabometyx approval in 2nd-line liver cancer by the January 14 PDUFA date, which will help drive sales to $873M in 2019.
09/21/18
PIPR
09/21/18
NO CHANGE
Target $29
PIPR
Overweight
Piper Jaffray reiterates Overweight rating on Exelixis after CHMP decision
After Ipsen (IPSEY) announced a positive CHMP decision for Cabometyx as a monotherapy for the treatment of hepatocellular carcinoma, Piper Jaffray analyst Edward Tenthoff noted that Exelixis (EXEL) is eligible for tiered royalties of 22-26% after $100M in sales of the drug in Europe. He expects final EMA approval in coming months and also expects the FDA to approve Cabometyx in liver cancer by the January 14 PDUFA date, Tenthoff tells investors. He reiterated an Overweight rating and $29 price target on Exelixis shares.
09/17/18
GUGG
09/17/18
INITIATION
Target $27
GUGG
Buy
Exelixis initiated with a Buy at Guggenheim
Target $27.
09/17/18
GUGG
09/17/18
INITIATION
Target $27
GUGG
Buy
Exelixis initiated with a Buy at Guggenheim
Guggenheim initiated Exelixis with a Buy and $27 price target.

TODAY'S FREE FLY STORIES

XLE

Energy Select Sector SPDR

$65.39

-0.17 (-0.26%)

08:19
11/15/18
11/15
08:19
11/15/18
08:19
Technical Analysis
Energy Select Sector SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

EIX

Edison International

$53.91

-1.65 (-2.97%)

08:19
11/15/18
11/15
08:19
11/15/18
08:19
Recommendations
Edison International analyst commentary  »

Edison International…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

XLY

Consumer Discretionary Sector SPDR

$106.97

-0.8 (-0.74%)

08:19
11/15/18
11/15
08:19
11/15/18
08:19
Technical Analysis
Consumer Discretionary Sector SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

XLB

S&P Select Materials SPDR

$53.94

-0.08 (-0.15%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Technical Analysis
S&P Select Materials SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CEIX

Consol Energy

$40.57

-0.72 (-1.74%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Conference/Events
Consol Energy management to meet with Seaport Global »

Meeting to be held in New…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 15

    Nov

XLU

Utilities SPDR

$54.48

-0.58 (-1.05%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Technical Analysis
Utilities SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

XLP

Consumer Staples Sector SPDR

$56.01

-0.34 (-0.60%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Technical Analysis
Consumer Staples Sector SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BERY

Berry Global

$45.91

-0.49 (-1.06%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Hot Stocks
Berry Global sees FY19 adjusted free cash flow $670M »

The company said,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 15

    Nov

XLV

Health Care Select Sector SPDR

$90.31

-0.75 (-0.82%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Technical Analysis
Health Care Select Sector SPDR: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

KBH

KB Home

$20.80

-0.135 (-0.64%)

08:18
11/15/18
11/15
08:18
11/15/18
08:18
Downgrade
KB Home rating change  »

KB Home downgraded to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

IWM

iShares Trust Russell 2000 Index Fund

$149.46

-1.05 (-0.70%)

08:17
11/15/18
11/15
08:17
11/15/18
08:17
Technical Analysis
iShares Trust Russell 2000 Index Fund: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

DIA

Diamonds Fund ETF

$251.14

-2.02 (-0.80%)

08:17
11/15/18
11/15
08:17
11/15/18
08:17
Technical Analysis
Diamonds Fund ETF: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPY

SPDR S&P 500 ETF Trust

$270.19

-1.81 (-0.67%)

08:17
11/15/18
11/15
08:17
11/15/18
08:17
Technical Analysis
SPDR S&P 500 ETF Trust: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

XLF

Financial Select Sector

$26.38

-0.36 (-1.35%)

08:17
11/15/18
11/15
08:17
11/15/18
08:17
Technical Analysis
Financial Select Sector: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

UMPQ

Umpqua Holdings

$19.06

-0.65 (-3.30%)

08:17
11/15/18
11/15
08:17
11/15/18
08:17
Hot Stocks
Umpqua Holdings appoints Frank Namdar CCO »

Umpqua Holdings announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SMH

Market Vectors Semiconductor

$92.97

0.36 (0.39%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Technical Analysis
Market Vectors Semiconductor: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

QQQ

Invesco QQQ Trust

$165.14

-1.34 (-0.80%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Technical Analysis
Invesco QQQ Trust: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

MARK

Remark Holdings

$3.28

-0.23 (-6.55%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Recommendations
Remark Holdings analyst commentary  »

Remark Holdings price…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 04

    Dec

$COMP

Nasdaq Composite

$0.00

(0.00%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Technical Analysis
Nasdaq Composite: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NDX

Nasdaq 100 Index

$0.00

(0.00%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Technical Analysis
Nasdaq 100 Index: Pivot points »

The following are the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BERY

Berry Global

$45.91

-0.49 (-1.06%)

08:16
11/15/18
11/15
08:16
11/15/18
08:16
Earnings
Berry Global reports Q4 adjusted EPS 90c, consensus 87c »

Reports Q4 revenue $2.1B,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 15

    Nov

08:15
11/15/18
11/15
08:15
11/15/18
08:15
General news
Jobless Claims to be reported at 08:30 »

Week of 11/10 Jobless…

08:15
11/15/18
11/15
08:15
11/15/18
08:15
General news
Empire State Mfg Survey General Business Conditions Index to be reported at 08:30 »

November Empire State Mfg…

08:15
11/15/18
11/15
08:15
11/15/18
08:15
General news
Retail Sales less autos to be reported at 08:30 »

October Retail Sales less…

08:15
11/15/18
11/15
08:15
11/15/18
08:15
General news
Retail Sales to be reported at 08:30 »

October Retail Sales will…

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.