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OVID

Ovid Therapeutics

$5.35

-0.64 (-10.68%)

09:04
10/25/18
10/25
09:04
10/25/18
09:04

Ovid Therapeutics announces additional data from STARS trial at AACAP

Ovid Therapeutics announced additional exploratory efficacy data and analyses from the company's Phase 2 STARS trial that further support the potential of OV101, a novel selective extrasynaptic GABAA receptor agonist that is being investigated to treat Angelman syndrome. Angelman syndrome is a life-long genetic disorder that is characterized by a variety of signs and symptoms, and for which there are no FDA-approved medicines or an established treatment paradigm. The additional efficacy data and analyses are being presented in a poster at the American Academy of Child and Adolescent Psychiatry, or AACAP, annual meeting. The additional data and analyses revealed changes in certain sleep parameters and motor domains in both adults and adolescents in the OV101 15 mg once-daily dose group as further described in the detailed STARS data summary below. Ovid believes these observed changes may have contributed to the statistically significant improvement observed in the clinician-rated clinical global impressions of improvement, or CGI-I, symptoms overall in the 15 mg once-daily OV101 dose group compared to placebo after 12 weeks of treatment, as reported in the topline data from the STARS trial on August 6. CGI-I is a global measure commonly used in clinical trials that allows the clinician to capture improvement in a constellation of clinical symptoms.

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OVID Ovid Therapeutics
$5.35

-0.64 (-10.68%)

08/10/18
PIPR
08/10/18
NO CHANGE
Target $20
PIPR
Overweight
Piper sees value coming back into Ovid shares after pullback
Shares of Ovid Therapeutics have pulled back following the recent Angelman's data release, but investors underappreciate the exploratory nature of what was the first study of its kind, Piper Jaffray analyst Tyler Van Buren tells investors in a research note. Further, he believes the FDA will give flexibility in designing a registrational program for OV101 given the lack of treatments option and the significant unmet needs that exists for these patients. The analyst maintains an Overweight rating on Ovid with a $20 price target, believing share value will accrue as investors get a greater appreciation for the OV101 program and opportunity.
08/06/18
PIPR
08/06/18
NO CHANGE
Target $20
PIPR
Overweight
Ovid Therapeutics shares should recover from here, says Piper Jaffray
Piper Jaffray analyst Tyler Van Buren attributes Ovid Therapeutics' selloff to the lack of statistical significance on the domain-based endpoints in the Phase 2 STARS trial, but he believes the shares will recover from these levels as appreciation for the just-reported data grows and as the report of OV935 proof of concept dEE data near year-end approaches. The analyst, who thinks the dEE data has "exciting potential," keeps an Overweight rating and $20 price target on Ovid shares, which are down 35% to $6.20 in afternoon trading.
05/18/18
PIPR
05/18/18
INITIATION
Target $20
PIPR
Overweight
Ovid Therapeutics assumed with an Overweight at Piper Jaffray
Piper Jaffray analyst Tyler Van Buren assumed coverage of Ovid Therapeutics with an Overweight rating and $20 price target. The company is enrolling genetically-defined orphan populations with preclinical models that have demonstrated encouraging results, Van Buren tells investors in a research note.
04/20/18
LTCO
04/20/18
INITIATION
Target $27
LTCO
Buy
Ovid Therapeutics initiated with a Buy at Ladenburg
Ladenburg analyst Michael Higgins initiated Ovid Therapeutics with a Buy and $27 price target.

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