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ONS

Oncobiologics

$0.98

0.08 (8.89%)

09:01
11/06/18
11/06
09:01
11/06/18
09:01

Oncobiologics advances ONS-5010 into wet AMD clinical trial

Oncobiologics announced that it has begun dosing patients in its first clinical trial for ONS-5010, a proprietary ophthalmic bevacizumab product candidate, in patients with wet age related macular degeneration. This first clinical study for ONS-5010, the Company's lead product candidate, is being conducted outside of the United States and is designed to serve as the first of two adequate and well controlled studies for wet AMD. The U.S. portion of the second study is scheduled to begin in early 2019 upon the submission of an investigational new drug application. The Company's wet AMD clinical program was reviewed at a successful end of Phase 2 meeting held with the U.S. FDA conducted earlier in 2018. If the program is successful, it will support the Company's plans to submit for regulatory approval in multiple markets in 2020. The Company is developing ONS-5010 as an innovative therapy and not using the biosimilar drug development pathway.

ONS Oncobiologics
$0.98

0.08 (8.89%)

01/29/18
LEHM
01/29/18
DOWNGRADE
Target $1.5
LEHM
Equal Weight
Oncobiologics downgraded to Equal Weight from Overweight at Barclays
Barclays analyst Douglas Tsao downgraded Oncobiologics to Equal Weight and cut his price target for the shares to $1.50 from $11. The analyst sees a lack of clarity in the go forward business. His new price target reflects removal of U.S. Humira and Avastin biosimilar opportunities and the addition of contract manufacturing and emerging market revenues.
01/29/18
01/29/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Starbucks (SBUX) downgraded to Market Perform from Outperform at Bernstein with analyst Sara Senatore saying she believes the business mix is clearly shifting toward China just not fast enough to offset the U.S. The analyst also lowered her price target for $64 from $67. 2. CBS (CBS) downgraded to Market Perform from Outperform at Wells Fargo with analyst Marci Ryvicker saying she does not like the company's potential merger with Viacom (VIAB). 3. Oncobiologics (ONS) downgraded to Equal Weight from Overweight at Barclays with analyst Douglas Tsao saying he sees a lack of clarity in the go forward business. 4. Alliance Data (ADS) downgraded to Market Perform from Outperform at Cowen with analyst George Mihalos saying believes the shares are reaching fair value and that many of its catalysts from 2018 will not repeat over the intermediate term. 5. Fortis (FTS) downgraded to Underperform from Sector Perform at National Bank. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

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CLF

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$NSD

NASDAQ Market Internals

$0.00

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$NYE

NYSE Market Internals

$0.00

(0.00%)

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BSX

Boston Scientific

$34.13

-1.16 (-3.29%)

12:10
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U.S. equities remain under pressure »

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AMAT

Applied Materials

$36.27

1.85 (5.37%)

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FX Action: USD-CAD »

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FB

Facebook

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EGRX

Eagle Pharmaceuticals

$48.01

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SDRL

Seadrill

$14.63

-1.84 (-11.17%)

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EROS

Eros International

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LB

L Brands

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SCO

Scor ADR

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NOAH

Noah Holdings

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DWT

Britannia Bulk

$11.85

1.62 (15.84%)

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BECN

Beacon Roofing

$28.44

0.7 (2.52%)

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Downgrade
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  • 13

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TJX

TJX

$46.84

-2.13 (-4.35%)

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Earnings
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  • 20

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TJX

TJX

$46.84

-2.13 (-4.35%)

11:58
11/20/18
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11:58
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11:58
Earnings
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  • 20

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UNP

Union Pacific

$142.91

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Options
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  • 27

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11:53
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Conference/Events
William Blair industrial technology analysts to hold a group luncheon »

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