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INFI

Infinity Pharmaceuticals

$2.39

-0.03 (-1.24%)

13:01
11/11/18
11/11
13:01
11/11/18
13:01

Infinity Pharmaceuticals reports data from MARIO-1 Phase 1b study

Infinity Pharmaceuticals announced that data to be presented at the 33rd Annual Meeting of the Society for Immunotherapy of Cancer demonstrated preliminary evidence that IPI-549 in combination with Opdivo is clinically active in indications not expected to respond to Opdivo alone. In particular, evidence of reversal of resistance to Opdivo included a partial response in a patient with metastatic melanoma who progressed on immediate prior Opdivo therapy. IPI-549 plus Opdivo also resulted in a 26% reduction of tumor target lesions in a patient with chemotherapy-resistant triple negative breast cancer, a tumor type intrinsically resistant to checkpoint inhibition. The data also included long-term follow up on sustained partial responses in two patients from combination dose escalation: one with microsatellite stable gallbladder cancer and one with adrenocortical carcinoma. The observed early clinical activity from the combination expansion, in addition to findings from the monotherapy cohorts, including associated translational data, support on-mechanism proof of concept for IPI-549. Infinity is evaluating IPI-549 in MARIO-1, a Phase 1b study in approximately 200 patients with advanced solid tumors. Additionally, Infinity is planning to initiate MARIO-275, a global, randomized Phase 2 study to evaluate the effect of adding IPI-549 to Opdivo in approximately 150 checkpoint-inhibitor naive advanced urothelial cancer patients who have progressed or recurred following treatment with platinum-based chemotherapy.

  • 15

    Nov

INFI Infinity Pharmaceuticals
$2.39

-0.03 (-1.24%)

05/31/18
GHSC
05/31/18
INITIATION
Target $4
GHSC
Buy
Infinity Pharmaceuticals initiated with a Buy at Seaport Global
Seaport Global analyst Corey Davis initiated Infinity Pharmaceuticals with a Buy and $4 price target. The analyst believes 2018 could be a "break-out" year with new data on its lead compound IPI-549 in combination with Opdivo for various tumor types with June 4 at ASXO form its "dose escalation" cohort, Q2 initial data from the "dose expansion" cohort, and more mature data from the "dose expansion" later in the year.
05/31/18
05/31/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Wyndham Hotels & Resorts (WH) initiated with a Buy at Jefferies and an Overweight at JPMorgan. 2. Nxt-ID (NXTD) initiated with a Buy at Euro Pacific. 3. Infinity Pharmaceuticals (INFI) initiated with a Buy at Seaport Global. 4. Edwards Lifesciences (EW) and Medtronic (MDT) were initiated with an Outperform at Raymond James. 5. Rollins (ROL) initiated with a Hold at Stifel. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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BA

Boeing

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DHT

DHT Holdings

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PLL

Piedmont Lithium

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-0.24 (-1.82%)

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T

AT&T

$32.11

0.03 (0.09%)

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Boeing

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BA

Boeing

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TMO

Thermo Fisher

$263.74

4.68 (1.81%)

CAT

Caterpillar

$142.08

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ANTM

Anthem

$250.75

6.71 (2.75%)

NSC

Norfolk Southern

$201.68

0.15 (0.07%)

GD

General Dynamics

$182.33

5.27 (2.98%)

NOC

Northrop Grumman

$292.59

9.73 (3.44%)

BSX

Boston Scientific

$35.88

0.95 (2.72%)

BIIB

Biogen

$229.89

1.15 (0.50%)

SIRI

Sirius XM

$6.14

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SWK

Stanley Black & Decker

$147.37

1.89 (1.30%)

DPZ

Domino's Pizza

$270.25

4.19 (1.57%)

KNX

Knight-Swift

$35.01

0.295 (0.85%)

OC

Owens Corning

$55.60

1.24 (2.28%)

GNTX

Gentex

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T

AT&T

$32.11

0.03 (0.09%)

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BSX

Boston Scientific

$35.88

0.95 (2.72%)

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FFHL

Fuwei Films

$2.66

0.05 (1.92%)

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NWE

NorthWestern

$68.06

0.46 (0.68%)

19:12
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MNOV

MediciNova

$10.68

0.77 (7.77%)

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MANH

Manhattan Associates

$61.13

0.96 (1.60%)

, CSL

Carlisle

$128.57

1.94 (1.53%)

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MANH

Manhattan Associates

$61.13

0.96 (1.60%)

CSL

Carlisle

$128.57

1.94 (1.53%)

TER

Teradyne

$44.60

-0.26 (-0.58%)

EBAY

eBay

$36.66

0.51 (1.41%)

SNAP

Snap

$11.99

0.46 (3.99%)

SIX

Six Flags

$52.39

0.8 (1.55%)

NAVI

Navient

$12.45

0.38 (3.15%)

BSX

Boston Scientific

$35.88

0.95 (2.72%)

ABBV

AbbVie

$78.65

0.55 (0.70%)

IRBT

iRobot

$130.42

1.71 (1.33%)

SPN

Superior Energy

$4.97

-0.02 (-0.40%)

RHI

Robert Half

$68.83

1.46 (2.17%)

TSS

TSYS

$102.25

1.46 (1.45%)

SYK

Stryker

$186.95

4.905 (2.69%)

EW

Edwards Lifesciences

$180.89

2.64 (1.48%)

TXN

Texas Instruments

$116.37

1.43 (1.24%)

AMTD

TD Ameritrade

$54.28

0.61 (1.14%)

BURL

Burlington Stores

$161.96

1.76 (1.10%)

CP

Canadian Pacific

$219.33

0.215 (0.10%)

LRN

K12

$36.23

0.805 (2.27%)

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GE

General Electric

$9.34

0.02 (0.21%)

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HAS

Hasbro

$100.34

12.32 (14.00%)

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ABBV

AbbVie

$78.65

0.55 (0.70%)

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TSS

TSYS

$102.25

1.46 (1.45%)

18:19
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Earnings
TSYS backs FY19 EPS view $4.75-$4.90, consensus $4.86 »

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HCC

Warrior Met Coal

$31.78

1.21 (3.96%)

18:16
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Warrior Met Coal declares $4.41 special cash dividend »

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LBTYA

Liberty Global

$27.28

-0.01 (-0.04%)

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  • 07

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:09
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18:09
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Valmont reaffirms FY19 revenue view up 7%-8% »

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:08
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18:08
Earnings
Valmont narrows FY19 EPS view to $8.30-$8.90 from $8.10-$8.90 »

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:07
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Earnings
Valmont reports Q1 EPS $1.84 ex-items, consensus $1.74 »

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HNHPF

Hon Hai Precision

$0.00

(0.00%)

18:06
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18:06
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BSX

Boston Scientific

$35.88

0.95 (2.72%)

17:47
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17:47
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Breaking Hot Stocks news story on Boston Scientific »

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TPL

Texas Pacific Land Trust

$896.00

0.19 (0.02%)

17:45
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17:45
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Texas Pacific Land Trust says trustee nominee Eric Oliver should be disqualified »

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