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ALPN

Alpine Immune Sciences

$4.80

-0.01 (-0.21%)

18:42
11/11/18
11/11
18:42
11/11/18
18:42

Piper Jaffray bullish on Alpine after 'robust' ALPN-202 preclinical activity

Piper Jaffray analyst Edward Tenthoff notes that Alpine Immune Sciences presented two posters at SITC for immuno-oncology variable Immunoglobulin Domain candidates. The analyst points out that new preclinical data on ALPN-202, which co-engages PD-L1 and CTLA-4 to selectively stimulates CD28 on T-cells, demonstrated "robust" anti-tumor activity in vivo compared to single agent anti-PD-1 durvalumab. He believes SITC data indicated vIgDs unique co-engagement at the synpase generates superior anti-tumor activity, and says Alpine will file an IND on lead autoimmune vIgD ALPN-101 by year-end 2018 and could prove superior to Orencia with preclinical data at ASH. Tenthoff reiterates an Overweight rating and $12 price target on the shares.

  • 15

    Nov

  • 27

    Nov

ALPN Alpine Immune Sciences
$4.80

-0.01 (-0.21%)

06/28/18
OPCO
06/28/18
INITIATION
Target $13
OPCO
Outperform
Alpine Immune Sciences initiated with an Outperform at Oppenheimer
Oppenheimer analyst Mark Breidenbach started Alpine Immune Sciences with an Outperform rating and $13 price target, citing his belief that the company's differentiated platform technology could significantly improve the performance of checkpoint modulators, which have revolutionized the treatment of certain cancers and autoimmune disorders.
08/13/18
RAJA
08/13/18
INITIATION
Target $13
RAJA
Outperform
Alpine Immune Sciences initiated with an Outperform at Raymond James
Raymond James analyst Reni Benjamin initiated Alpine Immune Sciences (ALPN) with an Outperform and $13 price target. Benjamin said the company has a unique platform technology utilizing directed evolution to generate multi-functional single compounds. The analyst believes the platform is on the verge of a significant validation inflection point given a "slew" of preclinical results demonstrating activity in both autoimmune disease adn oncology, combined with early stage partnership with Kite, a Gilead (GILD) company.
09/27/18
PIPR
09/27/18
INITIATION
Target $12
PIPR
Overweight
Alpine Immune Sciences initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Alpine Immune Sciences with an Overweight rating and $12 price target. The company is developing proprietary variant Ig domain technology to create novel immunotherapies to treat cancer and autoimmune diseases, Tenthoff tells investors in a research note. He points out that Alpine ended Q2 with cash of $70 M and is trading at a market cap of only $88M.
09/27/18
09/27/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Apple (AAPL) initiated with an Overweight at JPMorgan. 2. UPS (UPS) initiated with a Sector Weight at KeyBanc. 3. Cigna (CI) initiated with an Overweight at Cantor Fitzgerald. 4. Restoration Robotics (HAIR) initiated with an Outperform at William Blair. 5. Alpine Immune Sciences (ALPN) initiated with an Overweight at Piper Jaffray. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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MRTX

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BREW

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ROX

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0.0122 (1.36%)

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PRT

PermRock Royalty Trust

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GBCI

Glacier Bancorp

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1.36 (3.28%)

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ERJ

Embraer

$22.81

-0.59 (-2.52%)

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AICAF

Air China

$0.00

(0.00%)

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CEA

China Eastern Airlines

$28.64

-0.09 (-0.31%)

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MS

Morgan Stanley

$44.48

1.59 (3.71%)

, BBT

BB&T

$47.55

1.2 (2.59%)

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MS

Morgan Stanley

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BB&T

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MTB

M&T Bank

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KEY

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FAST

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FDC

First Data

$21.27

3.72 (21.20%)

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  • 03

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VEON

Veon

$2.56

-0.03 (-1.16%)

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AMZN

Amazon.com

$1,682.84

7.84 (0.47%)

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GS

Goldman Sachs

$197.03

17.12 (9.52%)

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  • 03

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TSLA

Tesla

$346.03

1.78 (0.52%)

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  • 16

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Cars.com

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$1.32

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FOLD

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FUL

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PLXS

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CSX

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AAPL

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BAC

Bank of America

$28.44

1.89 (7.12%)

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  • 16

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NEWR

New Relic

$90.47

1.38 (1.55%)

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TME

Tencent Music

$12.99

0.57 (4.59%)

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ASCMA

Ascent Capital

$0.40

-0.0499 (-11.09%)

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CMS

CMS Energy

$50.56

0.34 (0.68%)

18:19
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CMS Energy initiated at Goldman Sachs »

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  • 10

    Feb

DTE

DTE Energy

$111.73

0.48 (0.43%)

18:15
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18:15
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