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ALPN

Alpine Immune Sciences

$4.80

-0.01 (-0.21%)

18:42
11/11/18
11/11
18:42
11/11/18
18:42

Piper Jaffray bullish on Alpine after 'robust' ALPN-202 preclinical activity

Piper Jaffray analyst Edward Tenthoff notes that Alpine Immune Sciences presented two posters at SITC for immuno-oncology variable Immunoglobulin Domain candidates. The analyst points out that new preclinical data on ALPN-202, which co-engages PD-L1 and CTLA-4 to selectively stimulates CD28 on T-cells, demonstrated "robust" anti-tumor activity in vivo compared to single agent anti-PD-1 durvalumab. He believes SITC data indicated vIgDs unique co-engagement at the synpase generates superior anti-tumor activity, and says Alpine will file an IND on lead autoimmune vIgD ALPN-101 by year-end 2018 and could prove superior to Orencia with preclinical data at ASH. Tenthoff reiterates an Overweight rating and $12 price target on the shares.

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ALPN Alpine Immune Sciences
$4.80

-0.01 (-0.21%)

06/28/18
OPCO
06/28/18
INITIATION
Target $13
OPCO
Outperform
Alpine Immune Sciences initiated with an Outperform at Oppenheimer
Oppenheimer analyst Mark Breidenbach started Alpine Immune Sciences with an Outperform rating and $13 price target, citing his belief that the company's differentiated platform technology could significantly improve the performance of checkpoint modulators, which have revolutionized the treatment of certain cancers and autoimmune disorders.
08/13/18
RAJA
08/13/18
INITIATION
Target $13
RAJA
Outperform
Alpine Immune Sciences initiated with an Outperform at Raymond James
Raymond James analyst Reni Benjamin initiated Alpine Immune Sciences (ALPN) with an Outperform and $13 price target. Benjamin said the company has a unique platform technology utilizing directed evolution to generate multi-functional single compounds. The analyst believes the platform is on the verge of a significant validation inflection point given a "slew" of preclinical results demonstrating activity in both autoimmune disease adn oncology, combined with early stage partnership with Kite, a Gilead (GILD) company.
09/27/18
PIPR
09/27/18
INITIATION
Target $12
PIPR
Overweight
Alpine Immune Sciences initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Alpine Immune Sciences with an Overweight rating and $12 price target. The company is developing proprietary variant Ig domain technology to create novel immunotherapies to treat cancer and autoimmune diseases, Tenthoff tells investors in a research note. He points out that Alpine ended Q2 with cash of $70 M and is trading at a market cap of only $88M.
09/27/18
09/27/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Apple (AAPL) initiated with an Overweight at JPMorgan. 2. UPS (UPS) initiated with a Sector Weight at KeyBanc. 3. Cigna (CI) initiated with an Overweight at Cantor Fitzgerald. 4. Restoration Robotics (HAIR) initiated with an Outperform at William Blair. 5. Alpine Immune Sciences (ALPN) initiated with an Overweight at Piper Jaffray. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

BA

Boeing

$374.04

-0.98 (-0.26%)

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SPY

SPDR S&P 500 ETF Trust

$292.86

2.56 (0.88%)

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$0.00

(0.00%)

20:54
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Lighthizer, Mnuchin to hold trade talks in China on April 30th, Bloomberg says »

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SPDR S&P 500 ETF Trust

$292.86

2.56 (0.88%)

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DHT

DHT Holdings

$5.17

0.075 (1.47%)

20:46
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DHT Holdings rating change at Evercore ISI »

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PLL

Piedmont Lithium

$12.98

-0.24 (-1.82%)

20:45
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T

AT&T

$32.11

0.03 (0.09%)

, BA

Boeing

$374.04

-0.98 (-0.26%)

20:25
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T

AT&T

$32.11

0.03 (0.09%)

BA

Boeing

$374.04

-0.98 (-0.26%)

TMO

Thermo Fisher

$263.74

4.68 (1.81%)

CAT

Caterpillar

$142.08

-0.28 (-0.20%)

ANTM

Anthem

$250.75

6.71 (2.75%)

NSC

Norfolk Southern

$201.68

0.15 (0.07%)

GD

General Dynamics

$182.33

5.27 (2.98%)

NOC

Northrop Grumman

$292.59

9.73 (3.44%)

BSX

Boston Scientific

$35.88

0.95 (2.72%)

BIIB

Biogen

$229.89

1.15 (0.50%)

SIRI

Sirius XM

$6.14

0.03 (0.49%)

SWK

Stanley Black & Decker

$147.37

1.89 (1.30%)

DPZ

Domino's Pizza

$270.25

4.19 (1.57%)

KNX

Knight-Swift

$35.01

0.295 (0.85%)

OC

Owens Corning

$55.60

1.24 (2.28%)

GNTX

Gentex

$22.09

0.23 (1.05%)

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T

AT&T

$32.11

0.03 (0.09%)

20:09
04/23/19
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AT&T's WarnerMedia to sell 30 Hudson Yards for ~$2.2B »

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BSX

Boston Scientific

$35.88

0.95 (2.72%)

20:07
04/23/19
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Boston Scientific analyst commentary at Piper Jaffray »

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FFHL

Fuwei Films

$2.66

0.05 (1.92%)

19:16
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04/23
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NWE

NorthWestern

$68.06

0.46 (0.68%)

19:12
04/23/19
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Earnings
NorthWestern reports Q1 adjusted EPS $1.23, consensus $1.18 »

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MNOV

MediciNova

$10.68

0.77 (7.77%)

19:03
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MANH

Manhattan Associates

$61.13

0.96 (1.60%)

, CSL

Carlisle

$128.57

1.94 (1.53%)

18:58
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Fly Intel: After Hours Movers »

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MANH

Manhattan Associates

$61.13

0.96 (1.60%)

CSL

Carlisle

$128.57

1.94 (1.53%)

TER

Teradyne

$44.60

-0.26 (-0.58%)

EBAY

eBay

$36.66

0.51 (1.41%)

SNAP

Snap

$11.99

0.46 (3.99%)

SIX

Six Flags

$52.39

0.8 (1.55%)

NAVI

Navient

$12.45

0.38 (3.15%)

BSX

Boston Scientific

$35.88

0.95 (2.72%)

ABBV

AbbVie

$78.65

0.55 (0.70%)

IRBT

iRobot

$130.42

1.71 (1.33%)

SPN

Superior Energy

$4.97

-0.02 (-0.40%)

RHI

Robert Half

$68.83

1.46 (2.17%)

TSS

TSYS

$102.25

1.46 (1.45%)

SYK

Stryker

$186.95

4.905 (2.69%)

EW

Edwards Lifesciences

$180.89

2.64 (1.48%)

TXN

Texas Instruments

$116.37

1.43 (1.24%)

AMTD

TD Ameritrade

$54.28

0.61 (1.14%)

BURL

Burlington Stores

$161.96

1.76 (1.10%)

CP

Canadian Pacific

$219.33

0.215 (0.10%)

LRN

K12

$36.23

0.805 (2.27%)

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GE

General Electric

$9.34

0.02 (0.21%)

18:55
04/23/19
04/23
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18:55
Hot Stocks
DOJ says ex-GE engineer, Chinese man charged with theft of GE trade secrets »

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HAS

Hasbro

$100.34

12.32 (14.00%)

18:23
04/23/19
04/23
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18:23
Hot Stocks
Hasbro CEO: We expect to return to profitable growth this year »

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ABBV

AbbVie

$78.65

0.55 (0.70%)

18:21
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AbbVie says FDA approves SKYRIZI »

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TSS

TSYS

$102.25

1.46 (1.45%)

18:19
04/23/19
04/23
18:19
04/23/19
18:19
Earnings
TSYS backs FY19 EPS view $4.75-$4.90, consensus $4.86 »

Backs FY19 total revenue…

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HCC

Warrior Met Coal

$31.78

1.21 (3.96%)

18:16
04/23/19
04/23
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18:16
Hot Stocks
Warrior Met Coal declares $4.41 special cash dividend »

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LBTYA

Liberty Global

$27.28

-0.01 (-0.04%)

18:15
04/23/19
04/23
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18:15
Hot Stocks
Liberty Global names Lutz Shuler as Virgin Media CEO »

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  • 07

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:09
04/23/19
04/23
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18:09
General news
Valmont reaffirms FY19 revenue view up 7%-8% »

Reaffism FY19 capital…

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:08
04/23/19
04/23
18:08
04/23/19
18:08
Earnings
Valmont narrows FY19 EPS view to $8.30-$8.90 from $8.10-$8.90 »

Consensus is for FY19 EPS…

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VMI

Valmont

$131.14

-1.17 (-0.88%)

18:07
04/23/19
04/23
18:07
04/23/19
18:07
Earnings
Valmont reports Q1 EPS $1.84 ex-items, consensus $1.74 »

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HNHPF

Hon Hai Precision

$0.00

(0.00%)

18:06
04/23/19
04/23
18:06
04/23/19
18:06
Periodicals
Foxconn, Wisconsin renegotiating LCD plant contract, CNBC reports »

Wisconsin Governor Tony…

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BSX

Boston Scientific

$35.88

0.95 (2.72%)

17:47
04/23/19
04/23
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17:47
Hot Stocks
Breaking Hot Stocks news story on Boston Scientific »

Boston Scientific up over…

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TPL

Texas Pacific Land Trust

$896.00

0.19 (0.02%)

17:45
04/23/19
04/23
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17:45
Hot Stocks
Texas Pacific Land Trust says trustee nominee Eric Oliver should be disqualified »

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GLD

SPDR Gold Shares

$120.11

-0.26 (-0.22%)

17:41
04/23/19
04/23
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04/23/19
17:41
Hot Stocks
SPDR Gold Shares holdings fall to 749.63MT from 751.68MT »

This is the lowest level…

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SNAP

Snap

$11.99

0.46 (3.99%)

17:39
04/23/19
04/23
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04/23/19
17:39
Hot Stocks
Snap CEO says 'definitely excited about what we're seeing' with new Android app »

Says there is "a lot…

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