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LOXO

Loxo Oncology

$143.69

-15.62 (-9.80%)

19:51
11/14/18
11/14
19:51
11/14/18
19:51

Loxo Oncology initiated with a Strong Buy at Raymond James

Raymond James initiated Loxo Oncology with a Strong Buy and $235 price target.

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    Nov

LOXO Loxo Oncology
$143.69

-15.62 (-9.80%)

10/22/18
PIPR
10/22/18
NO CHANGE
Target $200
PIPR
Overweight
Loxo 'highly likely' to win FDA approval next month, says Piper Jaffray
Loxo Oncology (LOXO) this weekend reported updated durability data for the original 55 TRK fusion patients treated with larotrectinib plus initial efficacy data from 54 newly-evaluable patients, Piper Jaffray analyst Tyler Van Buren tells investors in a research note. He points out that the new patient dataset displayed a nearly identical response rate and that duration is tracking similarly with three quarters of patients maintaining a response out to a year. The updated larotrectinib data compare well to Roche's (RHHBY) competing entrectinib and makes the drug "highly likely" to be approved on or by the November 26 FDA action date, contends Van Buren. He reiterates an Overweight rating on Loxo Oncology with a $200 price target.
10/08/18
10/08/18
UPGRADE
Target $190

Outperform
Loxo Oncology upgraded to Outperform on LOXO-292 update at IFS Securities
As previously reported, IFS Securities analyst David Bouchey upgraded Loxo Oncology to Outperform from Market Perform, with $190 price target, after the company reported updated results from its Phase I/II trial for LOXO-292. The analyst believes the response rates for LOXO-292 continue to look "very strong," the safety data is "excellent" and early results show that these responses appear durable. So far, the drug has outperformed expectations, he adds.
10/08/18
IFSG
10/08/18
UPGRADE
IFSG
Outperform
Loxo Oncology upgraded to Outperform from Market Perform at IFS Securities
10/07/18
PIPR
10/07/18
NO CHANGE
Target $200
PIPR
Overweight
Loxo Oncology's 292 remains on top after RET data updates, says Piper Jaffray
Piper Jaffray analyst Tyler Van Buren reiterates an Overweight rating and $200 price target for Loxo Oncology (LOXO) after the company provided an update of the thyroid patients in the Phase I/II study of LOXO-292. The analyst highlights that in the largest patient population the response rate increased from 45% to 59% with three additional patients responding between 9 and 12 months. Blueprint Medicines' (BPMC) competing BLU-667 reported a 49% ORR in a similar patient population and recall that adverse events of hypertension are still a concern, he notes. Van Buren believes that the 667's safety profile could continue to look worse as it continues to administer the drug to patients at higher doses and that treatment discontinuations could increase. Overall, the analyst believes Loxo's 292 appears to be the superior RET inhibitor in development, both in terms of efficacy and safety and could easily become a $1B+ drug.

TODAY'S FREE FLY STORIES

LLY

Eli Lilly

$111.63

0.2 (0.18%)

21:03
08/22/19
08/22
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FL

Foot Locker

$42.00

2.24 (5.63%)

, HIBB

Hibbett Sports

$17.01

0.845 (5.23%)

20:25
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Earnings
Notable companies reporting before tomorrow's open »

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FL

Foot Locker

$42.00

2.24 (5.63%)

HIBB

Hibbett Sports

$17.01

0.845 (5.23%)

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RGR

Sturm, Ruger

$41.48

0.69 (1.69%)

, AOBC

American Outdoor Brands

$7.69

-0.01 (-0.13%)

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Sturm, Ruger

$41.48

0.69 (1.69%)

AOBC

American Outdoor Brands

$7.69

-0.01 (-0.13%)

VSTO

Vista Outdoor

$5.33

0.26 (5.13%)

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TOT

Total

$48.98

-0.18 (-0.37%)

19:16
08/22/19
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19:16
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19:16
Downgrade
Total rating change at Citi »

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KMPR

Kemper

$75.42

0.48 (0.64%)

19:14
08/22/19
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Downgrade
Kemper rating change at William Blair »

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CRM

Salesforce

$148.26

0.86 (0.58%)

, INTU

Intuit

$276.05

-0.29 (-0.10%)

18:52
08/22/19
08/22
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18:52
Hot Stocks
Fly Intel: After Hours Movers »

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CRM

Salesforce

$148.26

0.86 (0.58%)

INTU

Intuit

$276.05

-0.29 (-0.10%)

PVTL

Pivotal Software

$13.69

0.01 (0.07%)

CBLK

Carbon Black

$24.52

1.77 (7.78%)

HPQ

HP Inc.

$18.91

-0.04 (-0.21%)

RAVN

Raven

$31.36

-0.87 (-2.70%)

VMW

VMware

$148.15

0.11 (0.07%)

ROST

Ross Stores

$107.31

1.63 (1.54%)

GPS

Gap

$17.75

0.79 (4.66%)

HAS

Hasbro

$114.35

-1.06 (-0.92%)

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TLND

Talend

$39.24

0.12 (0.31%)

18:45
08/22/19
08/22
18:45
08/22/19
18:45
Hot Stocks
Talend CEO: We solve the first mile in the data journey »

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BA

Boeing

$354.47

14.44 (4.25%)

18:40
08/22/19
08/22
18:40
08/22/19
18:40
Periodicals
FAA intends to test Boeing MAX software on newer pilots, Reuters says »

Next month, the FAA…

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  • 03

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DB

Deutsche Bank

$7.17

0.155 (2.21%)

18:32
08/22/19
08/22
18:32
08/22/19
18:32
Periodicals
Deutsche Bank to pay $16M to settle corruption charges with SEC, Reuters says »

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SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$292.36

-0.04 (-0.01%)

18:28
08/22/19
08/22
18:28
08/22/19
18:28
Periodicals
Kudlow says U.S., Chinese negotiators held productive trade talks, Reuters says »

White House economic…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$292.36

-0.04 (-0.01%)

03/08/13
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GOOG

Alphabet

$1,188.53

-2.26 (-0.19%)

, GOOGL

Alphabet Class A

$1,190.41

0.15 (0.01%)

18:25
08/22/19
08/22
18:25
08/22/19
18:25
Hot Stocks
Google disabled 210 YouTube channels related to ongoing Hong Kong protests »

Google (GOOG) said in a…

GOOG

Alphabet

$1,188.53

-2.26 (-0.19%)

GOOGL

Alphabet Class A

$1,190.41

0.15 (0.01%)

FB

Facebook

$182.08

-1.48 (-0.81%)

TWTR

Twitter

$42.17

-0.63 (-1.47%)

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NUAN

Nuance

$17.31

-0.14 (-0.80%)

18:24
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18:24
Syndicate
Nuance files Form 10 registration statement for planned spin-off of Cerence »

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CRM

Salesforce

$148.26

0.86 (0.58%)

18:23
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Salesforce co-CEO: We had a very strong second quarter »

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RVLT

Revolution Lighting

$0.34

-0.0124 (-3.57%)

18:10
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Hot Stocks
Revolution Lighting discloses additional delisting determination from Nasdaq »

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IBKC

Iberiabank

$70.16

-0.38 (-0.54%)

18:05
08/22/19
08/22
18:05
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18:05
Hot Stocks
Iberiabank CEO Daryl Byrd sells over $840K in company shares »

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  • 23

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RMNI

Rimini Street

$4.77

-0.11 (-2.25%)

, ORCL

Oracle

$53.18

-0.08 (-0.15%)

18:02
08/22/19
08/22
18:02
08/22/19
18:02
Hot Stocks
San Fang Chemical switches to Rimini Street support for Oracle EBS »

Rimini Street (RMNI)…

RMNI

Rimini Street

$4.77

-0.11 (-2.25%)

ORCL

Oracle

$53.18

-0.08 (-0.15%)

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CRM

Salesforce

$148.26

0.86 (0.58%)

18:01
08/22/19
08/22
18:01
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Hot Stocks
Salesforce says Customer 360 will be huge growth driver over next decade »

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AAC

AAC Holdings

$0.60

-0.0327 (-5.17%)

17:57
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08/22
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Hot Stocks
AAC Holdings discloses NYSE listing notice »

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17:32
08/22/19
08/22
17:32
08/22/19
17:32
General news
Fed Balance Sheet Level data reported »

Week of 8/21 Fed Balance…

HPQ

HP Inc.

$18.91

-0.04 (-0.21%)

17:30
08/22/19
08/22
17:30
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17:30
Hot Stocks
HP Inc. says notebooks accounted for 39% of revenue in Q3 »

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17:28
08/22/19
08/22
17:28
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17:28
General news
Money Supply M2 Weekly Change data reported »

Week of 8/12 Money Supply…

TRPX

Therapix Biosciences

$2.35

(0.00%)

17:27
08/22/19
08/22
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17:27
Syndicate
Breaking Syndicate news story on Therapix Biosciences »

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GLD

SPDR Gold Shares

$141.38

-0.36 (-0.25%)

17:26
08/22/19
08/22
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Hot Stocks
SPDR Gold Shares holdings rise to 854.84MT to 851.91MT »

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VMW

VMware

$148.15

0.11 (0.07%)

17:19
08/22/19
08/22
17:19
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17:19
Earnings
VMware sees Q3 adjusted EPS $1.42, consensus $1.57 »

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CRWD

Crowdstrike

$93.04

-3.5 (-3.63%)

, CBLK

Carbon Black

$24.52

1.77 (7.78%)

17:14
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08/22
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Hot Stocks
Crowdstrike lower after Carbon Black acquisition »

Shares of cybersecurity…

CRWD

Crowdstrike

$93.04

-3.5 (-3.63%)

CBLK

Carbon Black

$24.52

1.77 (7.78%)

03/08/13
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  • 05

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