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FATE

Fate Therapeutics

$14.11

0.41 (2.99%)

08:22
11/30/18
11/30
08:22
11/30/18
08:22

Fate Therapeutics announces FDA acceptance of FT500 IND

Fate Therapeutics announced that the FDA has allowed its investigational new drug, or IND, Application for FT500, the company's universal, off-the-shelf natural killer, or NK, cell product candidate derived from a clonal master induced pluripotent stem cell, or iPSC, line. The clinical trial of FT500 is expected to be the first-ever clinical investigation in the U.S. of an iPSC-derived cell product. The company plans to initiate first-in-human clinical testing of FT500 in combination with checkpoint inhibitor therapy for the treatment of advanced solid tumors. This study is expected to evaluate the safety and tolerability of multiple doses of FT500, in multiple dosing cycles with nivolumab, pembrolizumab or atezolizumab, in subjects that have progressed or failed on checkpoint inhibitor therapy.

  • 30

    Nov

  • 01

    Dec

FATE Fate Therapeutics
$14.11

0.41 (2.99%)

11/11/18
PIPR
11/11/18
NO CHANGE
Target $23
PIPR
Overweight
Fate Therapeutics' NK100 update at SITC 'encouraging,' says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff notes that Fate Therapeutics updated Phase I NK100 data and provided new details on iPSC platform expansion at SITC. NK100 activity was observed in 7/14 AML, ovarian cancer and solid tumor patients, with seven patients receiving two infusions with NK100 cell persistence through Day 21 without compromised cytotoxicity or viability, he added, highlighting that NK100 is safe with no cytokine release syndrome or neurotoxicity even after multiple doses. Tenthoff is most excited for Fate's transformative iPSC platform enabling unprecedented scalable and homogeneous manufacturing. As expected, Fate found no adventitious agents and expects the first-ever IND on iPSC-derived Natural Killer cell therapy FT500 to clear by year-end 2018, he contends. Tenthoff adds that the company is developing a pipeline of iPSC cell therapies and will file an IND on FT516 by year-end 2018. He reiterates an Overweight rating and $23 price target on the shares.
11/05/18
JEFF
11/05/18
INITIATION
Target $17
JEFF
Buy
Fate Therapeutics initiated with a Buy at Jefferies
Jefferies analyst Biren Amin started Fate Therapeutics with a Buy rating and $17 price target. Natural killer cells possess advantageous cytotoxic properties distinct from T cells, and have demonstrated clinical efficacy against select cancer types, Amin tells investors in a research note. The analyst says Fate "offers a unique and potentially disruptive approach."
09/25/18
PIPR
09/25/18
NO CHANGE
Target $23
PIPR
Overweight
Fate Therapeutics price target lowered to $23 from $25 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff lowered his price target for Fate Therapeutics to $23 to account for dilution from the equity issuance. He estimates Fate now holds proforma cash of $223M to advance and expand its clinical pipeline of off-the-shelf Natural Killer cell and CAR-T therapies. The analyst reiterates an Overweight rating on the shares.
09/18/18
PIPR
09/18/18
NO CHANGE
Target $25
PIPR
Overweight
Fate Therapeutics price target raised to $25 from $20 at Piper Jaffray
After Fate Therapeutics announced a collaboration with ONO Pharmaceutical for the joint development and commercialization of two off-the-shelf CAR-T cell product candidates, Piper Jaffray analyst Edward Tenthoff said he likes the deal as it expands Fate's iPSC CAR-T pipeline while also giving the company $70M in near-term funding. Following the collaboration pact, Tenthoff increased his price target on Fate shares to $25 and reiterated an Overweight rating.

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AES

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AES

AES Corp.

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  • 04

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ICE

IntercontinentalExchange

$93.89

-0.58 (-0.61%)

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$0.00

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MAN

ManpowerGroup

$92.05

-0.355 (-0.38%)

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RHI

Robert Half

$58.01

-0.38 (-0.65%)

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HTZ

Hertz

$15.37

0.265 (1.76%)

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CAR

Avis Budget

$28.71

0.16 (0.56%)

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AMD

AMD

$39.52

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Initiation
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ARMK

Aramark

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HRB

H&R Block

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BV

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SERV

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PINE

Alpine Income Properties

$0.00

(0.00%)

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  • 22

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OTTW

Ottawa Bancorp

$13.39

-0.39 (-2.83%)

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MSFT

Microsoft

$149.46

-0.14 (-0.09%)

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  • 02

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SITC

Site Centers

$14.28

-0.275 (-1.89%)

18:24
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UAL

United Airlines

$90.96

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  • 03

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FAST

Fastenal

$35.15

-0.1 (-0.28%)

, GWW

Grainger

$312.66

0.305 (0.10%)

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Initiation
Fastenal, Grainger, HD Supply, MSC Industrial, Wesco initiated at Jefferies »

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GWW

Grainger

$312.66

0.305 (0.10%)

HDS

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$39.10

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MSM

MSC Industrial

$73.66

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WCC

Wesco

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SPGI

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INFO

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CSGP

CoStar Group

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GPS

Gap

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  • 21

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LB

L Brands

$17.18

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