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LGND

Ligand

$146.46

0.85 (0.58%)

10:08
12/10/18
12/10
10:08
12/10/18
10:08

Sermonix announces FDA acceptance of IND application for lasofoxifene

Sermonix Pharmaceuticals announced that the U.S. Food and Drug Administration accepted the company's Investigational New Drug application, indicating that Sermonix may proceed directly to a Phase 2 clinical study in the personalized medicine arena involving its lead investigational drug, lasofoxifene. The open-label, randomized, multi-center study is expected to begin enrollment in early 2019 and will evaluate the activity of oral lasofoxifene versus intramuscular fulvestrant for the treatment of postmenopausal women with locally advanced or metastatic estrogen receptor-positive (ER+)/HER2- breast cancer with an ESR1 mutation. A large amount of clinical data from earlier non-oncology development, along with new, compelling preclinical data have enabled Sermonix to commence directly into the Phase 2 study. The study will include postmenopausal women with ESR1 mutations, identified using a liquid biopsy clinical trial assay, who have progressed after aromatase inhibitor and CDK 4/6 inhibitor therapy. ESR1 mutations occur in up to 40 percent of women with metastatic breast cancer and may confer a worse prognosis and poor response to currently available endocrine treatments. Lasofoxifene is an investigational, nonsteroidal selective estrogen receptor modulator, which Sermonix licensed from Ligand Pharmaceuticals.

LGND Ligand
$146.46

0.85 (0.58%)

11/19/18
HCWC
11/19/18
NO CHANGE
Target $281
HCWC
Buy
Ligand recent selloff 'disconnected from reality,' says H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis says the recent selloff in shares of Ligand Pharmaceuticals is "disconnected from reality." In a research note titled "Stop the Insanity; Physician Survey Refutes Potential Bear Scenario; Reiterate Buy," the analyst tells investors that the recent weakness represents a "unique opportunity, even in these volatile markets." In the end, the focus is on Ligand's growing royalty revenue line and the current pipeline of over 178 partnered assets, Pantginis tells investors in a research note. He reiterates a Buy rating on the shares with a $281 price target.
11/13/18
SPHN
11/13/18
NO CHANGE
Target $200
SPHN
Overweight
Ligand recent pullback creates buying opportunity, says Stephens
Stephens analyst Drew Jones lowered his price target on Ligand shares to $200 from $248 following the recent pullback in the shares, but sees a buying opportunity given his expectations for solid royalty trends to remain intact. He thinks macro uncertainty continues to trump fundamentals, but believes company specific worries, such as Promacta competition, Kyprolis "lumpiness" and tough milestone comps for FY19, are "more distraction than material," he tells investors. Jones keeps an Overweight rating on Ligand shares.
11/08/18
HCWC
11/08/18
NO CHANGE
Target $281
HCWC
Buy
Ligand selloff a 'compelling accumulation opportunity,' says H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis says the recent weakness in shares of presents a "compelling accumulation opportunity." The investment case on Ligand is "unchanged" following its Q3 results, Pantginis tells investors in a research note. He views the selloff as "healthy," noting the stock is "letting off of some steam after significant out-performance." The analyst reiterates a Buy rating on Ligand with a $281 price target.
10/29/18
10/29/18
UPGRADE
Target $195

Buy
Ligand upgraded to Buy on 'strong' fundamentals at Roth Capital
As previously reported, Roth Capital analyst Scott Henry upgraded Ligand to Buy from Neutral following a 40% decline in the share price. The analyst argues that fundamentals remain strong and lowered 2019 outlook should be more conservative. Further, Henry targets upside to shares even with more conservative numbers. The analyst lowered his price target on the shares to $195 from $250.

TODAY'S FREE FLY STORIES

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General news
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DRH

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OOMA

Ooma

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AES

AES Corp.

$18.50

-0.115 (-0.62%)

19:08
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Earnings
AES backs FY19 adjusted EPS view $1.30-$1.38, consensus $1.33 »

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  • 04

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WM

Waste Management

$111.23

-1.305 (-1.16%)

, RSG

Republic Services

$86.78

-0.91 (-1.04%)

19:07
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Initiation
Waste Management, Republic Services, Waste Connections, Clean Harbors, Stericycle, Casella Waste, Covanta initiated  »

Jefferies initiates…

WM

Waste Management

$111.23

-1.305 (-1.16%)

RSG

Republic Services

$86.78

-0.91 (-1.04%)

WCN

Waste Connections

$89.54

-0.28 (-0.31%)

CLH

Clean Harbors

$84.70

-0.75 (-0.88%)

SRCL

Stericycle

$62.49

0.76 (1.23%)

CWST

Casella Waste

$43.70

-0.39 (-0.88%)

CVA

Covanta

$14.43

-0.14 (-0.96%)

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AES

AES Corp.

$18.50

-0.115 (-0.62%)

19:07
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AES Corp. says PUCO has modified DP&L rates »

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  • 04

    Dec

ICE

IntercontinentalExchange

$93.89

-0.58 (-0.61%)

, BTC

Bitcoin

$0.00

(0.00%)

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Hot Stocks
ICE announces launch of Bakkt Bitcoin Cash Settled Monthly Futures contract »

Intercontinental Exchange…

ICE

IntercontinentalExchange

$93.89

-0.58 (-0.61%)

BTC

Bitcoin

$0.00

(0.00%)

BITCOIN

Bitcoin

$0.00

(0.00%)

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MAN

ManpowerGroup

$92.05

-0.355 (-0.38%)

18:51
11/21/19
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Initiation
ManpowerGroup initiated at Jefferies »

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RHI

Robert Half

$58.01

-0.38 (-0.65%)

18:48
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Initiation
Robert Half initiated at Jefferies »

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HTZ

Hertz

$15.37

0.265 (1.76%)

18:46
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Initiation
Hertz initiated at Jefferies »

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CAR

Avis Budget

$28.71

0.16 (0.56%)

18:44
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Initiation
Avis Budget initiated at Jefferies »

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AMD

AMD

$39.52

-1.45 (-3.54%)

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AMD CEO: The key for us is product generation »

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  • 09

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CTAS

Cintas

$253.61

-5.78 (-2.23%)

, BFAM

Bright Horizons

$148.62

-3.92 (-2.57%)

18:42
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Initiation
Cintas, Bright Horizons, Aramark, H&R Block, BrightView, Rollins, ServiceMaster initiated at Jefferies »

Jefferies initiates…

CTAS

Cintas

$253.61

-5.78 (-2.23%)

BFAM

Bright Horizons

$148.62

-3.92 (-2.57%)

ARMK

Aramark

$42.42

-1.37 (-3.13%)

HRB

H&R Block

$24.34

-0.15 (-0.61%)

BV

BrightView

$16.79

-2.525 (-13.08%)

ROL

Rollins

$35.77

-0.8 (-2.19%)

SERV

ServiceMaster

$36.16

-0.42 (-1.15%)

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  • 21

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PINE

Alpine Income Properties

$0.00

(0.00%)

18:34
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Syndicate
Alpine Income Properties 7.5M share IPO priced at $19.00 »

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  • 22

    Nov

OTTW

Ottawa Bancorp

$13.39

-0.39 (-2.83%)

18:28
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Ottawa Bancorp approves stock buyback of 317,307 shares »

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MSFT

Microsoft

$149.46

-0.14 (-0.09%)

18:27
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11/21
18:27
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18:27
Periodicals
Microsoft says granted U.S. license to do business with Huawei, Bloomberg says »

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  • 02

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SITC

Site Centers

$14.28

-0.275 (-1.89%)

18:24
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Site Centers rating change at Stifel »

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UAL

United Airlines

$90.96

-0.72 (-0.79%)

, BA

Boeing

$366.47

-4.275 (-1.15%)

18:23
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Hot Stocks
United Airlines CEO: We don't think we are near a recession »

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UAL

United Airlines

$90.96

-0.72 (-0.79%)

BA

Boeing

$366.47

-4.275 (-1.15%)

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  • 03

    Dec

FAST

Fastenal

$35.15

-0.1 (-0.28%)

, GWW

Grainger

$312.66

0.305 (0.10%)

18:20
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18:20
Initiation
Fastenal, Grainger, HD Supply, MSC Industrial, Wesco initiated at Jefferies »

Jefferies initiates…

FAST

Fastenal

$35.15

-0.1 (-0.28%)

GWW

Grainger

$312.66

0.305 (0.10%)

HDS

HD Supply

$39.10

-0.21 (-0.53%)

MSM

MSC Industrial

$73.66

-0.125 (-0.17%)

WCC

Wesco

$53.09

-0.02 (-0.04%)

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  • 10

    Dec

  • 30

    Jan

SPGI

S&P Global

$264.34

-3.6 (-1.34%)

, INFO

IHS Markit

$71.62

-0.38 (-0.53%)

18:06
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Initiation
S&P Global, IHS Markit, Verisk Analytics, Gartner, FactSet, Equifax, TransUnion, CoStar Group initiated at Jefferies »

Jefferies initiates…

SPGI

S&P Global

$264.34

-3.6 (-1.34%)

INFO

IHS Markit

$71.62

-0.38 (-0.53%)

VRSK

Verisk Analytics

$144.45

0.12 (0.08%)

IT

Gartner

$158.00

0.06 (0.04%)

FDS

FactSet

$258.20

-3.65 (-1.39%)

EFX

Equifax

$137.97

-1.15 (-0.83%)

TRU

TransUnion

$84.90

-1.34 (-1.55%)

CSGP

CoStar Group

$587.66

-7.45 (-1.25%)

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  • 02

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  • 19

    Dec

  • 07

    Jan

GPS

Gap

$16.22

-0.05 (-0.31%)

17:59
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17:59
Periodicals
Gap to pull Old Navy brand from China in early 2020, Reuters reports »

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  • 21

    Nov

  • 05

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LB

L Brands

$17.18

1.78 (11.56%)

17:50
11/21/19
11/21
17:50
11/21/19
17:50
Hot Stocks
L Brands cancels Victoria's Secret Fashion Show for 'more current platforms' »

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  • 27

    Feb

WCC

Wesco

$53.09

-0.02 (-0.04%)

17:47
11/21/19
11/21
17:47
11/21/19
17:47
Initiation
Wesco initiated at Jefferies »

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MAN

ManpowerGroup

$92.05

-0.355 (-0.38%)

17:47
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Initiation
ManpowerGroup initiated at Jefferies »

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