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ZIOP

Ziopharm

$2.42

-0.23 (-8.68%)

07:03
12/19/18
12/19
07:03
12/19/18
07:03

Ziopharm and TriArm Therapeutics to co-develop CAR T therapies in Asia

Ziopharm and TriArm Therapeutics will launch Eden BioCell to lead clinical development and commercialization of Sleeping Beauty-generated CAR-T therapies in the People's Republic of China - including Macau and Hong Kong -, Taiwan and Korea. TriArm is a cell therapy company with operations in Germany, China and the United States that was formed by Panacea Venture Healthcare, a fund co-founded and managed by James Huang, Managing Partner of Kleiner Perkins Caufield & Byers China. For China, Taiwan and Korea, Ziopharm will license the rights to Eden BioCell for third-generation Sleeping Beauty-generated CAR-T therapies targeting the CD19 antigen. Eden BioCell will be owned 50-50 by Ziopharm and TriArm. TriArm has committed up to $35M to this joint venture. Ziopharm CEO Laurence Cooper and Panacea Venture Healthcare Managing Director James Huang will serve on Eden BioCell's Board of Directors and each party will share decision-making authority. TriArm will manage all clinical development to execute trials in China for Eden BioCell.

ZIOP Ziopharm
$2.42

-0.23 (-8.68%)

06/18/18
JPMS
06/18/18
DOWNGRADE
JPMS
Underweight
Ziopharm downgraded to Underweight from Neutral at JPMorgan
06/19/18
HCWC
06/19/18
NO CHANGE
Target $5.5
HCWC
Buy
Ziopharm selloff brings buying opportunity, says H.C. Wainwright
The clinical hold placed on Ziopharm's third generation point-of-care CAR-T program is unlikely to bring a significant delay, H.C. Wainwright analyst Swayampakula Ramakanth tells investors in a research note. The analyst views yesterday's 18% share pullback as a buying opportunity and reiterates a Buy rating on Ziopharm with a $5.50 price target. He notes that neither of the Ziopharm's clinical programs on Ad-RTS-hIL-12 or second generation CD19 and CD33 CAR-Ts has been affected by the clinical hold. The clinical hold is more akin to the FDA putting a "pause" on the investigational new drug application review process while the company prepares the response, Ramakanth argues.
11/15/18
RAJA
11/15/18
UPGRADE
RAJA
Outperform
Ziopharm upgraded to Outperform from Market Perform at Raymond James
11/15/18
11/15/18
UPGRADE
Target $5

Outperform
Ziopharm upgraded to Outperform at Raymond James
As previously reported, Raymond James analyst Reni Benjamin upgraded Ziopharm to Outperform from Market Perform, with a $5 price target. The analyst notes that the company provided an update on its cell and gene therapy programs in a recent conference call, saying it has severed its relationship with Intrexon, eliminating $157M million in preferred stock and significantly simplifying its corporate structure. Additionally, Ziopharm said that in conjunction with Steven Rosenberg and the NCI, it plans to utilize the Sleeping Beauty neoantigen platform to generate patient specific TCRs, with the filing of an IND expected by year end 2018/early 2019, he pointed out, adding that a cash infusion of $50M from long-term investors should extend the company's cash runway to Q2 of 2020.

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