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SESN

Sesen Bio

$1.47

0.05 (3.52%)

06:42
01/03/19
01/03
06:42
01/03/19
06:42

Sesen Bio's bladder cancer candidate shows positive preliminary Phase 3 results

Sesen Bio reported 'positive' preliminary efficacy data for the primary endpoint of its ongoing Phase 3 registration trial, the VISTA Trial, of Vicinium for the treatment of patients with high-grade non-muscle invasive bladder cancer who have been previously treated with bacillus Calmette-Guerin and deemed BCG-unresponsive. The data reported show clinically meaningful complete response rates in evaluable Carcinoma in situ patients at three, six, nine and 12 months of follow-up in the trial consistent with the data in the completed Phase 1 and Phase 2 clinical trials. Vicinium continues to be generally well-tolerated in treated patients. The data reported build upon preliminary three-month data presented from a subset of patients in May 2018 and are for the primary endpoint of the VISTA Trial, which is the complete response rate and duration of response in patients in Cohort. The patient population in Cohort 3 represents an opportunity for future label expansion, and the company plans to report efficacy data from this cohort, as well as the secondary endpoints in the VISTA Trial, in mid-2019. As of the December 3, 2018 data cut off, in patients across all three cohorts, 78% of adverse events were Grade 1 or 2. Complete 12-month efficacy data from all patients in the clinical trial are expected to be reported at a medical meeting in mid-2019.

  • 03

    Jan

SESN Sesen Bio
$1.47

0.05 (3.52%)

07/23/18
JEFF
07/23/18
INITIATION
Target $4
JEFF
Buy
Sesen Bio initiated with a Buy at Jefferies
Jefferies analyst Matthew Andrews started Sesen Bio with a Buy rating and $4 price target. The analyst sees share upside through 2019 driven by 12-month complete response data and FDA agreeing to accelerated approval for Vicinium.
07/09/18
ADAM
07/09/18
INITIATION
Target $5
ADAM
Buy
Sesen Bio initiated with a Buy at Canaccord
Canaccord analyst John Newman initiated Sesen Bio with a Buy rating and $5 price target, stating that he models $317M in U.S. peak sales by 2025 for its lead asset, Vicinium, assuming FDA approval in 2020.
05/22/18
HCWC
05/22/18
NO CHANGE
Target $3.5
HCWC
Buy
Sesen Bio price target raised to $3.50 from $2 at H.C. Wainwright
H.C. Wainwright analyst Swayampakula Ramakanth raised his price target for Sesen Bio to $3.50 saying the topline results from the ongoing Phase 3 Vista study of Vicinium bode well for a positive study. While 81% of treated patients reported adverse events, only 13% of patients reported serious adverse events and only 4% of patients reported adverse events that were believed to be treatment-related, Ramakanth tells investors in a research note. He believes the reported three month safety and efficacy results are well in-line with what Vicinium achieved in the previous Phase 2 study. The analyst expects Vicinium to reach the market by the end of 2019 and generate risk-adjusted revenues of $210M per year by 2030. Ramakanth keeps a Buy rating on Sesen Bio.

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CSCO

Cisco

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0.07 (0.16%)

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ABBV

AbbVie

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PRQR

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BILI

Bilibili

$16.39

-0.32 (-1.92%)

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WUBA

58.com

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BILI

Bilibili

$16.39

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58.com

$50.26

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BILI

Bilibili

$16.39

-0.32 (-1.92%)

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  • 18

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DDOG

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GVA

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ZS

Zscaler

$44.46

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Microsoft

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$44.46

-1.37 (-2.99%)

MSFT

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OKTA

Okta

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Upgrade
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PANW

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CRWD

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