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MRSN

Mersana Therapeutics

$4.04

-0.26 (-6.05%)

, TKPYY

Takeda Pharmaceutical

$0.00

(0.00%)

07:14
01/04/19
01/04
07:14
01/04/19
07:14

Mersana Therapeutics, Takeda Pharmaceutical to end collaboration on XMT-1522

Mersana Therapeutics (MRSN) announced that after a strategic evaluation the company will prioritize its resources to focus on the advancement of XMT-1536, an ADC candidate targeting NaPi2b. As a result, Mersana and its partner, Takeda (TKPYY), plan to terminate the co-development collaboration for XMT-1522. Mersana will work with investigators to ensure that patients benefitting from XMT-1522 will continue to have access to the therapy as needed.

MRSN

Mersana Therapeutics

$4.04

-0.26 (-6.05%)

TKPYY

Takeda Pharmaceutical

$0.00

(0.00%)

  • 11

    Jan

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    Jan

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    May

MRSN Mersana Therapeutics
$4.04

-0.26 (-6.05%)

09/17/18
JPMS
09/17/18
NO CHANGE
JPMS
Neutral
Mersana partial hold being lifted removes 'worst case scenario,' says JPMorgan
After Mersana announced that the FDA lifted the partial clinical hold on XMT1522 after reaching alignment on protocol changes, JPMorgan analyst Jessica Fye said the resolution of the partial hold was generally expected but still removes a "worst case scenario." Given the amendments increasing the time interval between dose escalation cohorts, she sees longer timelines to select the go-forward dose for XMT-1522. While Fye sees a potentially attractive opportunity for Mersana's ADC platform, she thinks patience will be required before generation of proof-of-concept data for XMT1522 and keeps a Neutral rating on Mersana shares.
09/17/18
HCWC
09/17/18
NO CHANGE
Target $23
HCWC
Buy
H.C. Wainwright boosts Mersana price target to $23 amid 23% selloff
H.C. Wainwright analyst Debjit Chattopadhyay raised his price target for Mersana Therapeutics to $23 after the company disclosed plans to reinstate dosing of new patients following the FDA's decision to lift the partial clinical hold on XMT-1522. The selloff in shares today could be related to the step back in development speed, which likely pushes relevant comparisons with peer sponsored programs into mid-2019, as well as the stock's 30% run-up since the partial clinical hold was disclosed on July 19, Chattopadhyay tells investors in a research note. The analyst says his new price target represents the XMT-1522 clinical program with "modest probabilities of success addressed in the valuation segment." He keeps a Buy rating on Mersana Therapeutics. The stock in midday trading is down 23%, or 3.32, to $11.06.
11/14/18
LEER
11/14/18
UPGRADE
LEER
Outperform
Mersana Therapeutics upgraded to Outperform from Market Perform at Leerink
11/14/18
11/14/18
UPGRADE
Target $14

Outperform
Mersana Therapeutics upgraded to Outperform on valuation at Leerink
As previously reported, Leerink analyst Jonathan Chang upgraded Mersana Therapeutics to Outperform from Market Perform, with $14 price target. The analyst cited valuation as the stock is trading at historic lows. Chang notes that the company reported Q3 financial results and provided a pipeline update that was largely in-line with expectations, and points out that the next key catalysts for the stock will be initial XMT-1536 Phase I dose-escalation data in 1H19 and potential XMT-1522 Phase I update in mid-2019.
TKPYY Takeda Pharmaceutical
$0.00

(0.00%)

09/07/18
BREN
09/07/18
DOWNGRADE
BREN
Hold
Shire downgraded to Hold from Buy at Berenberg
Berenberg analyst Klara Fernandes downgraded Shire (SHPG) to Hold saying the current valuation offers limited potential upside ahead of the pending takeover by Takeda Pharmaceutical (TKPYY).
11/06/18
RHCO
11/06/18
NO CHANGE
Target $190
RHCO
Buy
Shire price target lowered to $190 from $205 at SunTrust
SunTrust analyst John Boris lowered his price target on Shire (SHPG) to $190 to reflect the impact of the USD appreciation against GBP while also lowering his FY18 EPS view to $15.11 from $15.18. The analyst notes that the investment focus for Shire falls on the November 20th vote by E.U. regulators on its merger with Takeda (TKPYY), adding that the company is on track to secure that approval and for shareholders to vote on the deal in January of next year.
12/12/18
RHCO
12/12/18
DOWNGRADE
Target $175
RHCO
Hold
Shire downgraded to Hold at SunTrust on Takeda merger
As reported earlier, SunTrust analyst John Boris downgraded Shire (SHPG) to Hold from Buy and lowered his price target to $175 from $190. The analyst cites the changes in FX rates and Takeda (TKPYY) share price in shifting his price target, but expects the deal to close under the same terms on January 8th with no "meaningful hurdles" left to clear until then.
12/20/18
WBLR
12/20/18
DOWNGRADE
WBLR
Market Perform
Shire downgraded to Market Perform from Outperform at William Blair
William Blair analyst Tim Lugo downgraded Shire (SHPG) to Market Perform to reflect the pending takeover by Takeda Pharmaceutical (TKPYY).

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EEX

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