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INSY

Insys Therapeutics

$4.47

0.05 (1.13%)

06:03
01/09/19
01/09
06:03
01/09/19
06:03

Insys Therapeutics reports results of PK study for epinephrine nasal spray

INSYS Therapeutics announced the results of a dose-finding pharmacokinetic study of its epinephrine nasal spray. These results identified a dose that showed a PK profile similar to that of intramuscular injection of EpiPen and Adrenalin, both of which are treatments for anaphylaxis, an acute, life-threatening allergic reaction. The dose-finding PK study, INS015-18-124, was a single-dose, open-label, randomized, four-treatment, four-way crossover study to assess the pharmacokinetics of two doses of epinephrine nasal spray and two reference products, EpiPen and Adrenalin in 49 healthy volunteers. Additionally, as reported on Jun. 14, 2018, the proof-of-concept PK study, demonstrated rapid drug absorption through the nasal mucosa and similar bioavailability to that of an intramuscular injection of EpiPen in nasal allergen challenged subjects.

  • 09

    Jan

INSY Insys Therapeutics
$4.47

0.05 (1.13%)

12/19/18
JANY
12/19/18
INITIATION
Target $11
JANY
Buy
Insys Therapeutics assumed with a Buy at Janney Montgomery Scott
Janney Montgomery Scott analyst Yun Zhong assumed coverage of Insys Therapeutics with a Buy rating and fair value estimate of $11, down from the firm's prior $16 estimate. Zhong said Insys is shifting focus from commercializing opioid products to developing cannabinoids and proprietary spray technology, adding that he views the heated discussion during a two-day FDA AdCom on naloxone earlier this week as a "clear sign" for an increased commercial opportunity for Insys. Zhong also believes the data from the cannabidiol programs, if positive, could unlock significant upside potential.
08/10/18
PIPR
08/10/18
NO CHANGE
Target $4
PIPR
Underweight
Insys DOJ settlement does not remove downside risk, says Piper Jaffray
Piper Jaffray analyst David Amsellem says the settlement with the Department of Justice does not mean there isn't downside risk in shares of Insys Therapeutics. For a $600M market capitalization, investors are getting a sublingual form of buprenorphine that was "roundly rejected" by an FDA panel in May, a cannabidiol product that has yet to demonstrate proof-of-concept in a well-controlled trial, a product in Syndros that has minimal sales after approximately one year of active promotion, and a declining asset in Subsys that has limited profitability, Amsellem tells investors in a research note following Insys' Q2 results. The analyst does not believe the shares are "adequately risk-adjusted." He reiterates an Underweight rating on Insys with a $4 price target.
03/09/18
PIPR
03/09/18
DOWNGRADE
Target $4
PIPR
Underweight
Insys Therapeutics downgraded to Underweight from Neutral at Piper Jaffray
Piper Jaffray analyst David Amsellem downgraded Insys Therapeutics to Underweight and cut his price target for the shares to $4 from $5. The analyst sees "no basis in reality" for the company's guidance of relatively stable total sales in 2018 versus 2017 given the nature of the opioid crisis. Further, the weak rollout of Syndros "also does not inspire confidence" in the 2018 guidance, Amsellem tells investors in a research note.

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Microsoft

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ENT

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LYB

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$89.14

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TCCO

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BMY

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TEN

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$36.29

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XRX

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TWTR

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ALLY

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