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ARQL

ArQule

$3.27

-0.22 (-6.30%)

07:05
01/09/19
01/09
07:05
01/09/19
07:05

Basilea announces 'positive' interim results from Phase 2 study of derazantinib

ArQule's partner, Basilea Pharmaceutica, announced results from the interim analysis of the registrational Phase 2 study with the orally administered pan-fibroblast growth factor receptor kinase inhibitor derazantinib. The analysis showed promising activity in patients with FGFR2 gene fusion-expressing intrahepatic cholangiocarcinoma and also confirmed the safety profile and tolerability of the drug candidate observed in previous clinical studies. The interim analysis in the ongoing registrational Phase 2 study was conducted after 42 patients had been enrolled in the study, with a subset of 29 evaluable patients who had at least one post-baseline imaging assessment. The objective response rate in the 29 evaluable patients was 21%. The disease control rate, reflecting the proportion of patients with a partial response or with stable disease, was 83%. The safety data obtained from all 42 patients enrolled to date was consistent with the results from previous clinical studies with derazantinib. ArQule COO Peter Lawrence said, "We are pleased with derazantinib's continued progress since it was licensed to Basilea Pharmaceutica in April 2018 in the US, EU, Japan and rest of world excluding Greater China. Under the terms of the license agreement, ArQule is eligible to receive up to $326M in regulatory and commercial milestone payments, and we look forward to further progress and updates from Basilea."

ARQL ArQule
$3.27

-0.22 (-6.30%)

01/07/19
PIPR
01/07/19
NO CHANGE
Target $235
PIPR
Overweight
Piper Jaffray views price paid for Loxo by Eli Lilly as fair
Piper Jaffray analyst Tyler Van Buren views the price of $235 per share paid by Eli Lilly (LLY) for Loxo Oncology (LOXO) as fair. The analyst says the price is near the $250-plus he previously thought was achievable in an acquisition scenario for Loxo. Other names in the precision medicine/oncology space that could be up today as a result of the buyout are Agios Pharmaceuticals (AGIO), ArQule (ARQL), Array BioPharma (ARRY), Blueprint Medicines (BPMC), Kura Oncology (KURA), Mirati Therapeutics (MRTX) and others, Van Buren tells investors in a research note. He raised his price target for Loxo Oncology to $235 from $200 and keeps an Overweight rating on the shares.
06/29/18
RILY
06/29/18
NO CHANGE
Target $7.5
RILY
Buy
ArQule price target raised to $7.50 from $4.00 at B. Riley FBR
B. Riley FBR analyst George Zavoico raised his price target for ArQule to $7.50 saying the positive clinical results with BTK and AKT inhibitors, along with the Basilea Pharma deal, add to his confidence. The analyst keeps a Buy rating on the shares.
06/12/18
06/12/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. InterDigital (IDCC) initiated with a Buy at Roth Capital. 2. Weight Watchers (WTW) initiated with an Overweight at JPMorgan and a Buy at DA Davidson. 3. Franklin Electric (FELE) initiated with a Neutral at DA Davidson. 4. ArQule (ARQL) initiated with an Outperform at Oppenheimer. 5. comScore (SCOR) initiated with a Buy at Loop Capital. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
06/11/18
OPCO
06/11/18
INITIATION
Target $7
OPCO
Outperform
ArQule initiated with an Outperform at Oppenheimer
Oppenheimer initiated ArQule with an Outperform and $7 price target.

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