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CRL

Charles River

$119.61

1.68 (1.42%)

08:03
01/11/19
01/11
08:03
01/11/19
08:03

Charles River, Atomwise form strategic alliance for AI-driven drug discovery

Charles River Laboratories International and Atomwise announced the formation of a strategic alliance that offers clients access to Atomwise's artificial intelligence-powered, structure-based, drug design technology, which allows scientists to predict how well a small molecule will bind to a target protein of interest. By removing sole reliance on empirical screening, AI enables drug researchers to test an extremely large and diverse chemical space in a matter of days and move through the optimization process quickly by focusing only on those compounds predicted to have improved target-binding attributes. This alliance combines two industry-leading drug discovery platforms: Atomwise's AI technology and Charles River's unique portfolio of end-to-end drug discovery and early-stage development capabilities and expertise. Leveraging Atomwise's AI technology and Charles River's integrated drug discovery platform has the potential to significantly streamline the hit discovery, hit-to-lead, and lead optimization process for clients' research efforts. Through the collaboration, Charles River will have access to Atomwise's AI technology to use with their existing portfolio of drug discovery services. Atomwise's patented technology can analyze billions of compounds and screen challenging target proteins in the small molecule drug discovery process. The advantages of Atomwise's AI technology will provide Charles River's clients with the opportunity to efficiently screen billions, and evaluate thousands, of compounds to optimize potency, selectivity, and toxicity during hit and lead identification before committing resources to assays or syntheses. As a result, Charles River's clients can expect increased efficiency and diversity in the drug discovery process, ultimately reducing the expected timeline for an integrated drug discovery project and expanding the chemical space examined.

CRL Charles River
$119.61

1.68 (1.42%)

09/25/18
FBCO
09/25/18
NO CHANGE
Target $128
FBCO
Neutral
Charles River price target raised to $128 from $121 at Credit Suisse
Credit Suisse analyst Erin Wilson Wright raised her price target for Charles River to $128 from $121 after meeting with management and coming away incrementally constructive on its long-term growth prospects. The analyst believes the company's high visibility on sustainable price increases for the foreseeable future should continue to offset ongoing RMS volume pressures. Wright reiterates a Neutral rating on the shares.
10/09/18
UBSW
10/09/18
INITIATION
Target $140
UBSW
Neutral
Charles River initiated with a Neutral at UBS
UBS analyst Daniel Brennan initiated Charles River with a Neutral rating and $140 price target.
10/09/18
UBSW
10/09/18
NO CHANGE
UBSW
UBS initiates coverage of Life Sciences and Diagnostics Tools sector
UBS analyst Daniel Brennan initiated coverage of the Life Sciences and Diagnostics Tools sector. He said demand is accelerating across his universe but valuations are extended. He expects strong fundamentals to continue into 2019 but he said selectivity is the key. In the group, his Buy ratings include Exact Sciences (EXAS), Iqvia (IQV), NanoString (NSTG), Syneos Health (SYNH) and Thermo Fisher (TMO).
11/08/18
RBCM
11/08/18
NO CHANGE
Target $147
RBCM
Outperform
Charles River price target raised to $147 from $131 at RBC Capital
RBC Capital analyst George Hill raised his price target on Charles River to $147 and kept his Outperform rating after its "solid" Q3 results. The analyst notes that the company's margin miss was also the result of the company investing back into its business to fortify its position as the "market leader in preclinical drug research". Hill believes that Charles River can win market share in an industry that already offers a favorable backdrop.

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