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MGNX

MacroGenics

$12.31

-0.2 (-1.60%)

07:59
01/22/19
01/22
07:59
01/22/19
07:59

MacroGenics price target lowered to $20 from $44 at Wedbush

Wedbush analyst David Nierengarten lowered his price target for MacroGenics to $20 from $44 following recent clinical updates and company guidance. In 2019, the analyst looks forward to the pivotal Phase 3 SOPHIA readout this quarter, where he looks for topline PFS study results to support margetuximab use in 3L/4L metastatic breast cancer with BLA submission in 2H19. Nierengarten sees upside to his valuation in the range $2-$6 depending on the strength of the data, with downside in the range of $2-$4. The analyst also notes that recently updated margetuximab data in gastric cancer at ASCO GI, although somewhat deteriorated from ESMO, is still positive and warrants further 2L investigation in combination with anti PD-1 antibody. He reiterates an Outperform rating on the shares.

MGNX MacroGenics
$12.31

-0.2 (-1.60%)

12/10/18
MSCO
12/10/18
NO CHANGE
MSCO
Equal Weight
MacroGenics hold doesn't impact other B7-H3 therapies, says Morgan Stanley
After MacroGenics announced the FDA has place a partial clinical hold on MGD009, Morgan Stanley analyst David Lebowitz noted that the hold is said to not impact other B7-H3 targeted therapies, including enoblituzumab and MGC018. Given MacroGenic's prior experience with flotetuzumab, he expects to see weakness in the shares on the open this morning, but Lebowitz points out that modifications for flotetuzumab allowed for better management of cytokine related AEs and that it continues to be studied. He keeps an Equal Weight rating on MacroGenics with a $21 price target. In pre-market trading, the stock is down $2.71, or 16.5%, to $13.70.
12/10/18
RAJA
12/10/18
DOWNGRADE
RAJA
Underperform
MacroGenics downgraded to Underperform from Outperform at Raymond James
12/04/18
RHCO
12/04/18
DOWNGRADE
Target $75
RHCO
Hold
Tesaro downgraded to Hold from Buy at SunTrust
SunTrust analyst Peter Lawson downgraded Tesaro (TSRO) to Hold from Buy and raised his price target to $75 from $65 after its announcement of being acquired by Glaxo SmithKline (GSK). The analyst believes that the $75 per share offer price is "fair" and expects the deal, which he views as potentially positive for peers and for the biotech tape, to be completed in Q1 of 2019. Lawson anticipates that other companies with DNA damage response targeting drugs such as Sierra Oncology (SRRA), as well as immunoefficiency pipeline peers including MacroGenics (MGNX), Array Biopharma (ARRY), and Deciphera Pharmaceuticals (DCPH) could benefit from the announcement.
09/10/18
BTIG
09/10/18
INITIATION
Target $30
BTIG
Buy
MacroGenics assumed with a Buy at BTIG
BTIG analyst Thomas Shrader assumed MacroGenics with a Buy rating and a price target if $30, saying he is positive on its DART and TRIDENT multi-functional antibodies programs and its Fc Optimization technology that "allows antibodies to interact more strongly with immune effector cells that resolve antibody-antigen complexes". The analyst contends that while the company's monoclonal antibodies, or mAb, development space is "crowded", MacroGenics offers "nearly two decades of tough won experience" and over two years of cash runway to give its "deep pipeline" multiple opportunities to "turn heads".

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