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LXRX

Lexicon

$5.96

-1.73 (-22.50%)

08:07
01/22/19
01/22
08:07
01/22/19
08:07

Lexicon price target lowered to $36 from $42 at Wedbush

Wedbush analyst Liana Moussatos lowered her price target for Lexicon to $36 from $42, while reiterating an Outperform rating on the shares as she sees the split AdComm selloff "overdone." On January 17, the Endocrinologic and Metabolic Drug Advisory Committee had a split vote for/against approval of sotagliflozin as potentially the first oral antidiabetic drug used as an adjunct to insulin to improve glycemic control in adults with type 1 diabetes, she notes. The analyst points out that this was the first AdComm for an oral medication for T1D and the non-diabetes experts may have been thinking about T2D A1c drops not on insulin when criticizing the clinical meaningfulness of the 0.2%-0.4% placebo adjusted A1c drop for sotagliflozin. Moussatos also believes the DKA safety issue was "blown out of proportion." Even if FDA issues a CRL on March 22nd to allow more time to develop a RMS or even REMS, the analyst anticipates approval.

  • 22

    Mar

LXRX Lexicon
$5.96

-1.73 (-22.50%)

01/22/19
SBSH
01/22/19
NO CHANGE
Target $14
SBSH
Buy
Lexicon price target lowered to $14 from $26 at Citi
Citi analyst Yigal Nochomovitz lowered his price Lexicon Pharmaceuticals (LXRX) to $14 following last week's FDA panel on sotagliflozin. The analyst now believes Sanofi (SNY) and Lexicon will likely need to conduct a pilot study on a Risk Evaluation and Mitigation Strategies program for mitigating diabetic ketoacidosis risk before the FDA will consider approving the drug. He keeps a Buy rating on Lexicon.
05/22/18
WEDB
05/22/18
NO CHANGE
Target $42
WEDB
Outperform
Lexicon price target raised to $42 from $40 at Wedbush
02/23/18
NEED
02/23/18
DOWNGRADE
NEED
Hold
Lexicon downgraded to Hold at Needham
As reported earlier, Needham analyst Alan Carr downgraded Lexicon Pharma to Hold from Buy after the company's U.S. Xermelo sales came in below expectations. Carr cites the ongoing challenges that include "low number of patient starts and a large number of Medicare patients receiving free drug under a company assistance program". While the company believes that patient starts are rebounding, the analyst contends that Xermelo launch trajectory implies a more modest peak in sales.
02/23/18
NEED
02/23/18
DOWNGRADE
NEED
Hold
Lexicon downgraded to Hold from Buy at Needham

TODAY'S FREE FLY STORIES

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General news
Fed's Rosengren warned that U.S. Q1 growth is likely to be weak »

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BBBY

Bed Bath & Beyond

$13.87

0.17 (1.24%)

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Activist firms seek to replace Bed Bath & Beyond board, CEO, WSJ says »

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  • 10

    Apr

RTN

Raytheon

$180.58

-0.82 (-0.45%)

, BA

Boeing

$370.52

8.37 (2.31%)

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  • 28

    May

20:35
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The "Summary of Opinions" from the BoJ's March meeting »

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WHD

Cactus

$36.03

1.225 (3.52%)

20:27
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Cactus VP of Operations sells 229K shares of common stock »

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CCL

Carnival

$56.67

-0.065 (-0.11%)

, MKC

McCormick

$143.88

1.58 (1.11%)

20:25
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Earnings
Notable companies reporting before tomorrow's open »

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CCL

Carnival

$56.67

-0.065 (-0.11%)

MKC

McCormick

$143.88

1.58 (1.11%)

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    Mar

CRTO

Criteo

$21.99

-3.4 (-13.39%)

20:19
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Downgrade
Criteo rating change at KeyBanc »

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SSNLF

Samsung

$0.00

(0.00%)

20:02
03/25/19
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Periodicals
Samsung sees weaker environment for display, memory in Q1, Bloomberg says »

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BA

Boeing

$370.52

8.37 (2.31%)

19:51
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Hot Stocks
U.S. MDA and Boeing Complete Historic Missile Defense Test »

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  • 28

    May

MCD

McDonald's

$185.66

-1.11 (-0.59%)

19:49
03/25/19
03/25
19:49
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19:49
Periodicals
McDonald's purchase price of Dynamic Yield above $300M, Bloomberg says »

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  • 30

    Apr

  • 28

    May

SSNLF

Samsung

$0.00

(0.00%)

19:32
03/25/19
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19:32
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19:32
Periodicals
Breaking Periodicals news story on Samsung »

Samsung sees Q1 below…

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AWR

American States Water

$71.51

0.505 (0.71%)

19:22
03/25/19
03/25
19:22
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19:22
Hot Stocks
American States Water CEO sells 12.4K shares of common stock »

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MEOH

Methanex

$56.35

-1.38 (-2.39%)

19:10
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03/25
19:10
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19:10
Hot Stocks
Methanex confirms receipt of director nominees notice from M&G »

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BECN

Beacon Roofing

$34.14

0.81 (2.43%)

, SAEX

SAExploration

$4.03

0.13 (3.33%)

18:55
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Hot Stocks
Fly Intel: After Hours Movers »

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BECN

Beacon Roofing

$34.14

0.81 (2.43%)

SAEX

SAExploration

$4.03

0.13 (3.33%)

IQ

iQIYI

$24.01

-0.86 (-3.46%)

MYOK

MyoKardia

$51.87

-2.44 (-4.49%)

CTMX

CytomX Therapeutics

$10.76

0.33 (3.16%)

03/08/13
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  • 26

    Mar

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    Mar

  • 21

    May

  • 27

    Mar

HPQ

HP Inc.

$18.97

-0.4 (-2.07%)

18:48
03/25/19
03/25
18:48
03/25/19
18:48
Periodicals
HP lawyer tells court Autonomy's Lynch inflated sales data, Reuters says »

A lawyer for HP told a…

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  • 23

    Apr

PEGA

Pegasystems

$63.61

-0.27 (-0.42%)

18:45
03/25/19
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Hot Stocks
Pegasystems CEO: We are massively changing our marketing strategy »

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  • 22

    May

SMTC

Semtech

$52.59

-0.38 (-0.72%)

18:32
03/25/19
03/25
18:32
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18:32
Hot Stocks
Semtech CEO sells 25K shares of common stock »

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  • 25

    Mar

TMO

Thermo Fisher

$268.89

5.015 (1.90%)

18:24
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Hot Stocks
Thermo Fisher CEO: We have a very disciplined M&A process »

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DJX

Dow Jones Industrial Average

$0.00

(0.00%)

, SPX

S&P 500

$0.00

(0.00%)

18:24
03/25/19
03/25
18:24
03/25/19
18:24
Periodicals
Parliament forces votes on Brexit plan options, Bloomberg reports »

Lawmakers of U.K.…

DJX

Dow Jones Industrial Average

$0.00

(0.00%)

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$278.99

-0.56 (-0.20%)

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MCD

McDonald's

$185.66

-1.11 (-0.59%)

18:23
03/25/19
03/25
18:23
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18:23
Hot Stocks
McDonald's to acquire Dynamic Yield, terms not stated »

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  • 30

    Apr

  • 28

    May

BA

Boeing

$370.52

8.37 (2.31%)

18:22
03/25/19
03/25
18:22
03/25/19
18:22
Periodicals
Boeing software fix to prevent repeated activiation of MCAS, Reuters says »

A Boeing software repair…

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  • 28

    May

ACHC

Acadia

$29.47

-0.59 (-1.96%)

17:58
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03/25
17:58
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Hot Stocks
Acadia says President Brett Turner leaving by mutual agreement »

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AAPL

Apple

$188.78

-2.33 (-1.22%)

17:41
03/25/19
03/25
17:41
03/25/19
17:41
Recommendations
Apple analyst commentary at Piper Jaffray »

Apple price target raised…

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  • 25

    Mar

  • 03

    Jun

ZFGN

Zafgen

$2.70

-0.15 (-5.26%)

17:38
03/25/19
03/25
17:38
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Hot Stocks
Armistice Capital reports 5.6% passive stake in Zafgen »

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NOC

Northrop Grumman

$268.56

0.27 (0.10%)

17:36
03/25/19
03/25
17:36
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17:36
Hot Stocks
Northrop Grumman awarded $245.05M Navy contract modification »

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