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SNNA

Sienna Biopharmaceuticals

$2.69

-0.11 (-3.93%)

09:09
02/08/19
02/08
09:09
02/08/19
09:09

Sienna Biopharmaceuticals announces SNA-001 trial meets primary endpoint

Sienna Biopharmaceuticals announced positive topline results from its pivotal trial of SNA-001 in conjunction with an 810 nm Diode laser, involving 65 patients. SNA-001, a topical pre-treatment to standard laser hair removal, was studied in women and men with white, gray, blonde, light red and light brown hair. The data showed SNA-001 met the primary endpoint of non-inferiority in hair reduction. In additional analyses, SNA-001 was statistically superior compared to vehicle+Laser, demonstrating up to a 31% reduction of light hair from baseline. SNA-001 was also evaluated in conjunction with a 1064 Nd:YAG and 755 nm Alexandrite laser for the reduction of light hair, showing a significant reduction from baseline and providing a potential path to regulatory clearance. These results, however, were less differentiated from the vehicle+Laser group compared to the 810 nm Diode laser study results. A third and final pivotal trial of SNA-001 in acne was also completed, demonstrating SNA-001 was non-inferior to laser therapy and providing a potential path to regulatory clearance.

SNNA Sienna Biopharmaceuticals
$2.69

-0.11 (-3.93%)

05/15/18
BMOC
05/15/18
NO CHANGE
Target $30
BMOC
Outperform
Sienna recent pullback brings good entry point, says BMO Capital
BMO Capital analyst Gary Nachman says Sienna Biopharmaceuticals' key catalysts are getting closer following its Q1 results. The company's important data readouts over the next year, beginning in Q3, include SNA-125 for psoriasis and atopic dermatitis, SNA-001 for light hair removal and acne, and SNA-120 for pruritis, Nachman tells investors in a post-earnings research note. He continues to see a "good risk/reward" on the shares into the data catalysts and remains confident in management's ability to execute. Nachman believes recent pullback in the stock creates a good entry point and reiterates an Outperform rating on Sienna Biopharmaceuticals with a $30 price target.
07/31/18
BMOC
07/31/18
NO CHANGE
Target $27
BMOC
Outperform
Sienna has bigger value drivers than SNA-001 in acne, says BMO Capital
BMO Capital analyst Gary Nachman called Sienna Biopharmaceuticals' announcement that SNA-001 failed in two of its three pivotal studies in acne an "unfortunate outcome," but he believes the bigger long-term value drivers for Sienna remain SNA-001 for light-hair removal and SNA-125 for psoriasis and atopic dermatitis. After removing any SNA-001 acne revenue from his estimates, Nachman lowered his price target on Sienna Biopharmaceuticals to $27 from $30 and keeps an Outperform rating on the shares.
10/10/18
BMOC
10/10/18
NO CHANGE
BMOC
BMO Capital confident in management, pipeline at Sienna Biopharmaceuticals
BMO Capital analyst Gary Nachman reiterated an Outperform rating on Sienna Biopharmaceuticals shares after recent investor meetings with management. The analyst is "cautiously optimistic" on SNA-001 in hair removal, sees good risk/reward for SNA-120 in pruritis associated with psoriasis and SNA-125 for atopic dermatitis, and over is "confident in management's ability to execute this pipeline with multiple shots on goal."
12/04/18
BMOC
12/04/18
NO CHANGE
Target $17
BMOC
Outperform
Sienna Biopharmaceuticals price target lowered to $17 from $27 at BMO Capital
BMO Capital analyst Gary Nachman lowered his price target on Sienna Biopharmaceuticals to $17 following its mixed Phase 2b results for SNA-120. The analyst states that the program missed the primary endpoint in pruritis, but showed surprisingly good results on key secondary endpoints in psoriasis and sees the management changing its course to focus on the psoriasis indication. Nachman keeps his Outperform rating on Sienna Biopharmaceuticals based on the potential of SNA-120 in psoriasis, even though he acknowledges its "increased development risk and questions regarding ultimate opportunity in a crowded psoriasis market".

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Post Holdings

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VMware

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MGM Resorts

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MGM Growth

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United Continental

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JetBlue

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NUE

Nucor

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NABZY

National Australia Bank

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TAP

Molson Coors

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MSFT

Microsoft

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Basic Energy

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MSFT

Microsoft

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MSFT

Microsoft

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RRGB

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T

AT&T

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Red Robin

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MSFT

Microsoft

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HBIO

Harvard Bioscience

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MSFT

Microsoft

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0.06 (0.04%)

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ISRG

Intuitive Surgical

$536.44

13.25 (2.53%)

17:38
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GLD

SPDR Gold Shares

$136.44

1.85 (1.37%)

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WAL

Western Alliance

$44.45

0.74 (1.69%)

17:29
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