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PFE

Pfizer

$41.67

-0.56 (-1.33%)

, MRK

Merck

$76.71

-0.82 (-1.06%)

17:47
02/11/19
02/11
17:47
02/11/19
17:47

FDA accepts Pfizer's Biologics License Application priority review for Bavencio

EMD Serono, the biopharmaceutical business of Merck (MRK) in the U.S. and Canada, and Pfizer (PFE) announced that the FDA has accepted for Priority Review the supplemental Biologics License Application for BAVENCIO in combination with INLYTA for patients with advanced renal cell carcinoma. The application has been given a target action date in June 2019. The submission is based on data from the pivotal Phase III JAVELIN Renal 101 trial, which were presented in a Presidential Symposium at the European Society of Medical Oncology 2018 Congress in Munich. In December 2017, the FDA granted Breakthrough Therapy Designation for BAVENCIO in combination with INLYTA for treatment-naive patients with advanced RCC. Despite available therapies, the outlook for patients with advanced RCC remains poor. Approximately 20% to 30% of patients are first diagnosed at the metastatic stage. The five-year survival rate for patients with metastatic RCC is approximately 12%. The clinical development program for avelumab, known as JAVELIN, involves at least 30 clinical programs and more than 9,000 patients evaluated across more than 15 different tumor types. In addition to RCC, these tumor types include breast, gastric/gastro-esophageal junction, and head and neck cancers, Merkel cell carcinoma, non-small cell lung cancer, and urothelial carcinoma.

PFE

Pfizer

$41.67

-0.56 (-1.33%)

MRK

Merck

$76.71

-0.82 (-1.06%)

  • 16

    Feb

  • 11

    Apr

  • 18

    May

PFE Pfizer
$41.67

-0.56 (-1.33%)

01/31/19
01/31/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pfizer (PFE) upgraded to Outperform from Neutral at Credit Suisse and to Buy from Hold at Argus. 2. Tiffany (TIF) upgraded to Overweight from Neutral at Atlantic Equities with analyst Daniela Nedialkova saying the pullback has been largely driven by macro concerns while fundamentals of the brand are strong and preliminary FY19 guidance is conservative. 3. Scotts Miracle-Gro (SMG) upgraded to Neutral from Underweight at JPMorgan with analyst Jeffrey Zekauskas citing valuation. 4. Geron (GERN) upgraded to Buy from Neutral at B. Riley FBR with analyst George Zavoico saying he believes investors should focus on the pivotal Phase III trial of imetelstat. 5. Ralph Lauren (RL) upgraded to Outperform from Market Perform at Telsey Advisory with analyst Dana Telsey saying the company's improving sakes, combined with ongoing margin expansion, should bolster its earnings. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
01/31/19
ARGS
01/31/19
UPGRADE
Target $55
ARGS
Pfizer upgraded to Buy from Hold at Argus
Argus analyst David Toung upgraded Pfizer (PFE) to Buy with a price target of $55, saying he anticipates an upward revenue inflection point in 2021 after flat sales in the second half of 2019 and first half of 2020. After cycling through Lyrica loss of exclusivity over the next year, the analyst anticipates Pfizer to benefit from optimized portfolio of assets as it completes its consumer healthcare business joint venture with GlaxoSmithKline (GSK). Toung adds that while he does not "expect major transformational deals", he does see the management pursuing "acquisitions and divestitures that improve long-term profitability".
01/31/19
01/31/19
UPGRADE
Target $47

Outperform
Pfizer upgraded to Outperform on new product story at Credit Suisse
As previously reported, Credit Suisse analyst Vamil Divan upgraded Pfizer to Outperform from Neutral and raised his price target on the shares to $47 from $45. The analyst notes that Pfizer has been working through a dark period with extensive patent expirations that have hampered the company's ability to grow, but that period is now nearing an end. Further, the analyst believes the company's new product story with multiple marketed and pipeline assets may be underappreciated.
01/31/19
ARGS
01/31/19
UPGRADE
ARGS
Buy
Pfizer upgraded to Buy from Hold at Argus
MRK Merck
$76.71

-0.82 (-1.06%)

02/05/19
BOFA
02/05/19
NO CHANGE
BOFA
Merck added to US 1 List, Allergan removed at BofA/Merrill
02/01/19
PIPR
02/01/19
NO CHANGE
Target $3
PIPR
Overweight
Piper says OncoSec's TAVO resensitizing anti-PD-1 progressers 'impressive'
After OncoSec (ONCS) reported updated data for the registrational KEYNOTE-695 study evaluating TAVO plus Merck's (MRK) Keytruda, Piper Jaffray analyst Edward Tenthoff noted that TAVO's ORR improved and called the fact that TAVO resensitized anti-PD-1 progressers "impressive." He reiterates an Overweight and $3 price target on OncoSec shares.
01/23/19
01/23/19
DOWNGRADE

Fly Intel: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Tesla (TSLA) downgraded to Underperform from Sector Perform at RBC Capital with analyst Joseph Spak saying the company's more "tactful messaging" conveys downward pressure to growth expectations and also sees the "realities" of Tesla becoming a volume player highlighting its "challenges to scale and deliver high volume at high ASPs/margins." 2. Lowe's (LOW) downgraded to Hold from Buy at Loop Capital with analyst Laura Champine saying she thinks she was previously too optimistic on Lowe's likely margin progression. 3. Williams-Sonoma (WSM) downgraded to Underweight from Equal Weight at Morgan Stanley with analyst Simeon Gutman saying he believes top and bottom-line pressures will intensify in 2019. 4. Merck (MRK) downgraded to Market Perform from Outperform at BMO Capital with analyst Alex Arfaei citing the company's over-dependence on Keytruda, the Street's high expectations, and his views on upcoming competitor trials combining for a more balanced risk-reward on Merck. 5. Pfizer (PFE) and Mylan (MYL) were downgraded to Neutral from Buy at UBS. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
01/23/19
01/23/19
DOWNGRADE
Target $80

Market Perform
Merck downgraded to Market Perform from Outperform at BMO Capital
As previously reported, BMO Capital analyst Alex Arfaei downgraded Merck to Market Perform and also lowered his Q4 earnings view to 98c from $1.12 while keeping his $80 price target on the shares. The analyst cites the company's over-dependence on Keytruda, the Street's high expectations, and his views on upcoming competitor trials combining for a more balanced risk-reward on Merck. Arfaei anticipates that Merck's revenue growth would slow after 2021 given the loss of exclusivity for Januvia, adding that the company's pipeline does not look "good enough to offset meaningful Keytruda disruptions."

TODAY'S FREE FLY STORIES

SQM

SQM

$37.08

-0.99 (-2.60%)

21:36
04/22/19
04/22
21:36
04/22/19
21:36
Initiation
SQM initiated  »

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NEE

NextEra Energy

$190.53

1.21 (0.64%)

, UTX

United Technologies

$136.99

-0.01 (-0.01%)

20:25
04/22/19
04/22
20:25
04/22/19
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

NEE

NextEra Energy

$190.53

1.21 (0.64%)

UTX

United Technologies

$136.99

-0.01 (-0.01%)

KO

Coca-Cola

$47.38

-0.11 (-0.23%)

VZ

Verizon

$58.38

0.33 (0.57%)

PG

Procter & Gamble

$106.04

-0.01 (-0.01%)

LMT

Lockheed Martin

$315.24

0.94 (0.30%)

SHW

Sherwin-Williams

$451.83

-0.61 (-0.13%)

TWTR

Twitter

$34.39

-0.01 (-0.03%)

STT

State Street

$69.92

-0.02 (-0.03%)

CNC

Centene

$48.19

0.04 (0.08%)

FITB

Fifth Third

$27.54

0.02 (0.07%)

NUE

Nucor

$57.00

-0.49 (-0.85%)

DGX

Quest Diagnostics

$85.17

-0.55 (-0.64%)

HAS

Hasbro

$88.02

-0.72 (-0.81%)

HOG

Harley-Davidson

$39.71

-1.2 (-2.93%)

PII

Polaris Industries

$98.93

0.185 (0.19%)

JBLU

JetBlue

$16.84

-0.13 (-0.77%)

GPK

Graphic Packaging

$12.98

0.035 (0.27%)

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LOGC

LogicBio Therapeutics

$12.28

0.15 (1.24%)

20:16
04/22/19
04/22
20:16
04/22/19
20:16
Hot Stocks
LogicBio Therapeutics' methylmalonic acidemia treatment gets FDA orphan status »

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  • 06

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RBB

RBB Bancorp

$19.18

-0.61 (-3.08%)

19:38
04/22/19
04/22
19:38
04/22/19
19:38
Earnings
RBB Bancorp reports Q1 EPS 51c, consensus 55c »

Reports Q1 NII $25.9M,…

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  • 23

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BEN

Franklin Resources

$35.04

-0.27 (-0.76%)

19:09
04/22/19
04/22
19:09
04/22/19
19:09
Periodicals
Franklin Resources to reduce workforce by up to 5%, Bloomberg says »

Franklin Resources…

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  • 26

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TSLA

Tesla

$262.90

-10.35 (-3.79%)

18:59
04/22/19
04/22
18:59
04/22/19
18:59
Periodicals
Consumer Reports: Tesla 'Autopilot' is no substitute for a human driver »

Consumer Reports states:…

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  • 22

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    Apr

CMRE

Costamare

$5.65

-0.09 (-1.57%)

, WHR

Whirlpool

$139.39

0.35 (0.25%)

18:56
04/22/19
04/22
18:56
04/22/19
18:56
Hot Stocks
Fly Intel: After Hours Movers »

UP AFTER EARNINGS: …

CMRE

Costamare

$5.65

-0.09 (-1.57%)

WHR

Whirlpool

$139.39

0.35 (0.25%)

CDNS

Cadence Design

$64.23

0.87 (1.37%)

BEDU

Bright Scholar

$11.38

-0.105 (-0.91%)

RRC

Range Resources

$9.83

0.07 (0.72%)

WAL

Western Alliance

$43.36

-0.89 (-2.01%)

ALDR

Alder Biopharmaceuticals

$12.77

0.1 (0.79%)

ROKU

Roku

$58.19

1.5 (2.65%)

VCYT

Veracyte

$23.04

0.02 (0.09%)

HARP

Harpoon Therapeutics

$11.35

-1.68 (-12.89%)

RMBS

Rambus

$11.80

-0.1 (-0.84%)

GRTS

Gritstone Oncology

$14.57

0.86 (6.27%)

GES

Guess

$16.66

-0.41 (-2.40%)

BHP

BHP Group

$55.14

0.19 (0.35%)

03/08/13
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03/06/13
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  • 05

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  • 25

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PCG

PG&E

$21.45

0.435 (2.07%)

18:52
04/22/19
04/22
18:52
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18:52
Hot Stocks
PG&E submits updated financing proposal for safety, reliability investments »

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18:40
04/22/19
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18:40
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18:40
General news
Treasury Closing Summary: »

Treasury Closing Summary:…

PCG

PG&E

$21.45

0.435 (2.07%)

18:39
04/22/19
04/22
18:39
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18:39
Hot Stocks
PG&E names Fred Buckman to board, expands board to 15 directors »

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AAPL

Apple

$204.62

0.79 (0.39%)

18:36
04/22/19
04/22
18:36
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18:36
Periodicals
Apple sued for $1B by teen claiming glitch in facial recognition software »

The report by…

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  • 30

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GOOG

Alphabet

$1,248.96

11.74 (0.95%)

, GOOGL

Alphabet Class A

$1,253.94

12.01 (0.97%)

18:36
04/22/19
04/22
18:36
04/22/19
18:36
Periodicals
Google walkout organizers say company retaliated against them, Wired says »

Two employee activists at…

GOOG

Alphabet

$1,248.96

11.74 (0.95%)

GOOGL

Alphabet Class A

$1,253.94

12.01 (0.97%)

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  • 29

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CTRA

Contura Energy

$56.27

0.5 (0.90%)

18:16
04/22/19
04/22
18:16
04/22/19
18:16
Hot Stocks
Contura Energy announces departure of CEO Kevin Crutchfield »

Contura Energy announced…

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  • 01

    May

BWEN

Broadwind Energy

$1.88

0.06 (3.30%)

18:04
04/22/19
04/22
18:04
04/22/19
18:04
Hot Stocks
Broadwind Energy announces $19.5M tower order »

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  • 23

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HLX

Helix Energy

$8.59

0.2 (2.38%)

18:04
04/22/19
04/22
18:04
04/22/19
18:04
Earnings
Helix Energy reports Q1 adjusted EPS 1c, consensus 0c »

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  • 23

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VBTX

Veritex

$25.92

-0.3 (-1.14%)

18:03
04/22/19
04/22
18:03
04/22/19
18:03
Earnings
Veritex reports Q1 diluted operating EPS 59c, consensus 55c »

Net interest margin…

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  • 23

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BCS

Barclays

$8.70

-0.05 (-0.57%)

18:00
04/22/19
04/22
18:00
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18:00
Periodicals
Barclays planning to slash bonuses for investment bankers, FT says »

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  • 25

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NVDA

Nvidia

$188.48

2.22 (1.19%)

, TSLA

Tesla

$262.90

-10.35 (-3.79%)

17:53
04/22/19
04/22
17:53
04/22/19
17:53
Periodicals
Nvidia calls Tesla claims on self-driving 'inaccurate', MarketWatch says »

Tesla (TSLA) claims that…

NVDA

Nvidia

$188.48

2.22 (1.19%)

TSLA

Tesla

$262.90

-10.35 (-3.79%)

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  • 22

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  • 10

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EFSC

Enterprise Financial

$42.49

-1.4 (-3.19%)

17:47
04/22/19
04/22
17:47
04/22/19
17:47
Hot Stocks
Enterprise Financial board raised dividend to 15c per share »

The company's Board…

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  • 23

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EFSC

Enterprise Financial

$42.49

-1.4 (-3.19%)

17:46
04/22/19
04/22
17:46
04/22/19
17:46
Earnings
Enterprise Financial reports Q1 EPS 67c, consensus 91c »

Reports Q1 revenue…

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  • 23

    Apr

17:45
04/22/19
04/22
17:45
04/22/19
17:45
General news
U.S. tax refunds »

U.S. tax refunds are on…

BPRN

Bank of Princeton

$32.30

(0.00%)

17:43
04/22/19
04/22
17:43
04/22/19
17:43
Earnings
Bank of Princeton reports Q1 EPS 3c, may not compare to consensus 53c »

Reports Q1 NII $9.9M,…

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  • 08

    May

LENS

Presbia

$0.56

-0.0034 (-0.61%)

17:29
04/22/19
04/22
17:29
04/22/19
17:29
Hot Stocks
Presbia discloses staff reduction, search for investor or strategic partner »

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WAL

Western Alliance

$43.36

-0.89 (-2.01%)

17:23
04/22/19
04/22
17:23
04/22/19
17:23
Earnings
Western Alliance reports Q1 adjusted EPS $1.16, consensus $1.09 »

Reports Q1 NII $247.3M…

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  • 23

    Apr

FCF

First Commonwealth

$13.26

-0.22 (-1.63%)

, SAN

Banco Santander

$5.12

-0.015 (-0.29%)

17:21
04/22/19
04/22
17:21
04/22/19
17:21
Hot Stocks
First Commonwealth to acquire 14 branches from Santander »

First Commonwealth…

FCF

First Commonwealth

$13.26

-0.22 (-1.63%)

SAN

Banco Santander

$5.12

-0.015 (-0.29%)

03/08/13
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  • 23

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