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CLBS

Caladrius

$5.30

0.07 (1.34%)

17:32
02/13/19
02/13
17:32
02/13/19
17:32

Caladrius says no improvement in primary endpoint in T-Rex study results

Caladrius announced top-line results from the Sanford Project: T-Rex study, a prospective, randomized, placebo-controlled, double-blind Phase 2a clinical trial of 110 subjects to evaluate the safety and efficacy of the company's CLBS03 as a treatment for recent-onset type 1 diabetes, or T1D, in adolescents. The initial analysis of the one-year follow-up data for all subjects shows that CLBS03 was well tolerated at the doses tested in the study, however, no improvement in the primary endpoint of preservation of C-peptide levels vs. placebo at one year was observed at the group level. As with many Phase 2a trials, the database from this study is large and the analysis and interpretation of all the information will require several months of intensive evaluation and will be critical to the decision regarding the next steps in development of CLBS03. In addition, the data from the 2-year follow-up, once complete, will afford supplemental information and are necessary to complete the evaluation of this therapy.

CLBS Caladrius
$5.30

0.07 (1.34%)

01/24/19
HCWC
01/24/19
NO CHANGE
Target $18.5
HCWC
Buy
Caladrius an 'intriguing opportunity' near cash levels, says H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis calls shares of Caladrius Biosciences an "intriguing opportunity" trading at near cash levels. A disconnect exists in evaluating the investment case for Caladrius' assets, which are supported by "compelling" clinical data, Pantginis tells investors in a research note. The analyst looks beyond the company's CD34+ cell therapy platform and highlights its second platform, T Regulatory Cell Therapy. He says the upcoming Phase 2 clinical readout using CLBS03 in Type 1 diabetes patients is the first major 2019 catalyst for Caladrius. Pantginis reiterates a Buy rating on the shares with an $18.50 price target.
11/20/18
HCWC
11/20/18
INITIATION
Target $18.5
HCWC
Buy
Caladrius assumed with a Buy at H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis assumed coverage of Caladrius Biosciences with a Buy rating and $18.50 price target. Based on a "strong management team and strong pipeline focus, Caladrius' thesis has been stabilized and is positioned for success," Pantginis tells investors in a research note. He points out the company is developing two technology platforms, with the lead based on CD34+ cells' playing a role in ischemic repair.
09/10/18
HCWC
09/10/18
NO CHANGE
Target $15
HCWC
Buy
Caladrius price target raised to $15 from $12 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised his price target for Caladrius Biosciences to $15 saying the shares are still undervalued following last month's Q2 results. The substantially lower than expected net loss "underscores prudent financial management," Selvaraju tells investors in a research note. The T-Rex Study Phase 2 trial of CLBS03 in Type 1 diabetes is slated to report top-line data in Q1 of 2019, the analyst points out. If the CLBS03 data are positive, the company could secure a partnership with a larger pharmaceutical firm for late-stage development, he contends. Selvaraju reiterates a Buy rating on Caladrius.
03/07/18
HCWC
03/07/18
NO CHANGE
Target $12
HCWC
Buy
Caladrius price target raised to $12 from $7 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised his price target for Caladrius Biosciences (CLBS) to $12 after the company acquired from Shire (SHPG) an exclusive worldwide license to data and regulatory filings for a late-stage CD34+ cell therapy program for the treatment of chronic myocardial ischemia targeting refractory angina. The deal "significantly enriches" Caladrius' existing pipeline and should provide an "additional attractive shot on goal" in the coming years, Selvaraju tells investors in a research note. He increased his valuation of the company to $120M from $60M and reiterates a Buy rating on the shares.

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SM

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