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FPRX

Five Prime

$11.86

0.19 (1.63%)

20:08
02/20/19
02/20
20:08
02/20/19
20:08

Five Prime doses first patient in phase 1B trial of FPA150

Five Prime Therapeutics announced that it initiated patient dosing in the Phase 1b dose expansion portion of the Phase 1a/1b clinical trial of FPA150, a first-in-class immuno-oncology antibody that targets B7-H4. The objective of the Phase 1b dose expansion is to evaluate the safety, tolerability, pharmacokinetics and potential preliminary clinical benefit of FPA150 monotherapy in patients with breast, ovarian and endometrial cancers that over-express B7-H4. A subgroup of patients in the Phase 1b portion will undergo pre- and on-treatment biopsies to assess the pharmacodynamic effects of FPA150 on the tumor and the tumor microenvironment, including changes in markers of tumor immune infiltrates and cytokine levels. Endpoints for the Phase 1b portion include objective response rate, duration of response and progression-free survival.

  • 04

    Mar

FPRX Five Prime
$11.86

0.19 (1.63%)

08/09/18
WELS
08/09/18
NO CHANGE
Target $35
WELS
Outperform
Five Prime price target lowered to $35 from $58 at Wells Fargo
Wells Fargo analyst Jim Birchenough lowered his price target for Five Prime to $35 from $58 following review of Q2 operating results and on disappointing update on Cabira in PVNS. The analyst reiterates an Outperform rating on the shares.
09/13/18
LEER
09/13/18
INITIATION
Target $24
LEER
Outperform
Five Prime resumed with an Outperform at Leerink
Leerink analyst Jonathan Chang resumed coverage of Five Prime with an Outperforn rating and $24 price target. While investors are cautious on cabiralizumab following updates at the Society for Immunotherapy of Cancer 2017 with limited visibility into future clinical updates and next development steps, MEDACorp KOLs he has spoken to remain positive on the approach. Additionally, Chang sees multiple sources of upside from his current valuation including opportunities for cabiralizumab beyond pancreatic cancer as well as Five Prime's advancing early stage pipeline including FPA150, FPT155, and BMS-986258.
01/17/19
WEDB
01/17/19
UPGRADE
WEDB
Outperform
Five Prime upgraded to Outperform from Neutral at Wedbush
01/17/19
01/17/19
UPGRADE
Target $16

Outperform
Five Prime upgraded to Outperform at Wedbush
As previously reported, Wedbush analyst Robert Driscoll upgraded Five Prime to Outperform from Neutral, with a $16 price target, given recent declines, which he believes leaves a more favorable risk/reward ahead of multiple clinical catalysts this year, and as the company focuses efforts on clinical development of its broad pipeline. Although 2019 data readouts will be centered on earlier stage assets, the analyst sees increased investor enthusiasm for the company's broad clinical pipeline, ahead of potential readouts for late stage assets next year.

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SEM

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KTOV

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OPRA

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ZAYO

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  • 23

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LHCG

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AMED

Amedisys

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HLM

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ALDR

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SHOP

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KTOV

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DMTK

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LDOS

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