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MGTA

Magenta Therapeutics

$18.66

1.27 (7.30%)

07:37
03/19/19
03/19
07:37
03/19/19
07:37

Magenta Therapeutics declared development candidate in C200 program

At the end of 2018, Magenta declared a development candidate in its C200 targeted conditioning program, which is designed to deplete stem cells in the bone marrow. The Company presented data at the TCT meeting in February 2019 on the development candidate, an anti-CD117 amanitin ADC, showing that it potently and selectively depleted hematopoietic stem cells in non-human primates while preserving the immune system. The ADC was well tolerated at the efficacious doses. Magenta has begun investigational new drug-enabling studies with this ADC and plans to develop it as a conditioning agent for stem cell gene therapy, in patients with genetic disorders such as sickle cell disease, where current conditioning regimens are toxic.

  • 19

    Mar

MGTA Magenta Therapeutics
$18.66

1.27 (7.30%)

07/16/18
JPMS
07/16/18
INITIATION
Target $18
JPMS
Overweight
Magenta Therapeutics initiated with an Overweight at JPMorgan
JPMorgan analyst Jessica Fye started Magenta Therapeutics with an Overweight rating and $18 price target. The analyst believes the company is positioned to transform the stem cell transplant market.
07/16/18
WEDB
07/16/18
INITIATION
Target $22
WEDB
Outperform
Magenta Therapeutics initiated with an Outperform at Wedbush
Wedbush analyst David Nierengarten started Magenta Therapeutics with an Outperform rating and $22 price target, noting that the company is developing its wholly-owned pipeline of therapies that aim to improve every major step of the hematopoietic stem cell transplant process, providing multiple shots on goal in an area largely overlooked by drug developers.
07/16/18
COWN
07/16/18
INITIATION
COWN
Outperform
Magenta Therapeutics initiated with an Outperform at Cowen
Cowen analyst Marc Frahm initiated Magenta Therapeutics with an Outperform rating as he believes the company's drug pipeline candidates have the potential to improve several aspects of a stem cell transplant and could transform the accessibility of transplantation. Frahm expects Magenta Therapeutics shares to appreciate as multiple candidates advance in development.
03/14/19
RAJA
03/14/19
INITIATION
RAJA
Outperform
Magenta Therapeutics initiated with an Outperform at Raymond James
Raymond James analyst Dane Leone initiated Magenta Therapeutics with an Outperform rating and a price target of $22. The analyst has three key reasons for recommending the stock: First, MGTA-456 has produced encouraging clinical results and "has an opportunity to significantly increase the utilization of cord blood units within transplant procedures." Second, MGTA-145 has the potential to improve patient outcomes and reduce costs associated with stem cell mobilization. Third, C200 can help alleviate a key headwind for the adoption of cell-based gene therapy.

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