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BLUE

Bluebird Bio

$156.20

2.65 (1.73%)

08:03
03/22/19
03/22
08:03
03/22/19
08:03

Bluebird Bio opens gene and cell therapy manufacturing facility

bluebird bio announced the official opening of its first wholly owned manufacturing facility in Durham, N.C., that will produce lentiviral vector for the company's investigational gene and cell therapies, including: bb2121 and bb21217 for the treatment of multiple myeloma and potentially LentiGlobin(TM) for the treatment of transfusion-dependent beta-thalassemia and sickle cell disease. Currently, bluebird employs approximately 50 scientists, engineers, manufacturing and operations personnel at the facility and is on track to grow to approximately 70 employees by the end of 2019. bluebird bio purchased the facility in November 2017. Once completed, the company will have invested more than $80M building a site equipped with multiple manufacturing suites capable of producing lentiviral vector. The facility also includes warehouse and quality control testing laboratories. The facility construction is substantially complete and equipment qualification is underway. Initially, bluebird bio expects the facility to produce clinical and commercial supply of lentiviral vector, which is a critical component of the company's gene and cell therapies. The facility is large enough to accommodate significant future expansion, including the possibility of manufacturing commercial drug product. In addition to the Durham facility, bluebird bio also has multi-year agreements with three manufacturing partners in the United States and Europe: Brammer Bio, Novasep, and MilliporeSigma. Each of these partners is collaborating with bluebird bio on production of lentiviral vector across all programs. bluebird bio also partners with Lonza and apceth Biopharma to produce drug product for Lenti-D and LentiGlobin.

  • 08

    Apr

BLUE Bluebird Bio
$156.20

2.65 (1.73%)

02/25/19
RHCO
02/25/19
NO CHANGE
Target $184
RHCO
Buy
Bluebird Bio price target lowered to $184 from $223 at SunTrust
SunTrust analyst Edward Nash lowered his price target on Bluebird Bio to $184 to reflect his updated expectations of E.U. LentiGlobin approval and bookings coming in 2020, rather 2019, along with a shallower penetration curve of the treatment in the U.S. The analyst is also keeping his Buy rating on the shares and sees Bluebird Bio as "best positioned to transition gene therapy from a scientific endeavor to a successful commercial proposition" given its "five potentially curative products in the clinic".
02/25/19
COWN
02/25/19
INITIATION
COWN
Outperform
Bluebird Bio coverage transferred with an Outperform at Cowen
Cowen analyst Yaron Werber assumed coverage on Bluebird Bio with an Outperform. The analyst believes that investors should have a strong interest in the stock, as bluebird has a deep pipeline, and is launching three drugs in 2019-2020, with "a slew of data" coming in 2019.
03/05/19
LEER
03/05/19
DOWNGRADE
LEER
Market Perform
Bluebird Bio downgraded to Market Perform from Outperform at SVB Leerink
03/05/19
03/05/19
DOWNGRADE
Target $145

Market Perform
Bluebird Bio downgraded to Market Perform on valuation at SVB Leerink
As previously reported, SVB Leerink analyst Mani Foroohar downgraded Bluebird Bio to Market Perform from Outperform, with a $145 price target. While the analyst remains optimistic on the company's ability to secure approval for BCMA, Lenti-D, and LentiGlobin programs, he believes the current valuation reflects these attractive fundamentals in line with his high probability of success assumptions.

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