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AVRO

Avrobio

$18.27

-0.77 (-4.04%)

07:13
03/25/19
03/25
07:13
03/25/19
07:13

Avrobio expects cash, cash equivalents to fund requirements into 2H20

As of December 31, 2018, AVROBIO had $126.3M in cash and cash equivalents, as compared to $6M in cash and cash equivalents as of December 31, 2017. This increase was primarily the result of the completion of the company's initial public offering completed in June 2018, which raised net proceeds of $104M, and the company's Series B financing completed in January 2018, which generated net proceeds of $58.3M. Based on the company's current operating plan, AVROBIO expects its cash and cash equivalents as of December 31, 2018 will enable the company to fund its operating expenses and capital expenditure requirements into the second half of 2020.

AVRO Avrobio
$18.27

-0.77 (-4.04%)

10/09/18
GUGG
10/09/18
INITIATION
GUGG
Buy
Avrobio initiated with a Buy at Guggenheim
Guggenheim analyst Whitney Ijem initiated Avrobio with a Buy rating and $35 price target, calling the two-day 61% sell off on the company's Ph1 Fabry data update an overreaction.
11/27/18
LEER
11/27/18
INITIATION
Target $27
LEER
Market Perform
Avrobio initiated with a Market Perform at Leerink
Leerink analyst Mani Foroohar initiated Avrobio with a Market Perform rating and a price target of $27.
11/27/18
LEER
11/27/18
INITIATION
LEER
Leerink initiates select Genetic Medicine names on increasing regulatory clarity
Leerink analyst Mani Foroohar initiated select Genetic Medicine stocks, stating that the field is "is rich with companies developing drugs" to treat rare diseases and that he is increasingly more bullish on "innovation velocity and increasing regulatory clarity in the sector. Based on his "balanced view of pricing dynamics", the analyst issues an Outperform rating on Wave Life Sciences (WVE), Rocket Pharmaceuticals (RCKT), Intellia Therapeutics (NTLA), Eidos Therapeutics (EIDX), Dicerna (DRNA) and Bluebird Bio (BLUE). The analyst likes Wave Life Sciences as a pure play on Oligotherapeutics and its stereopure chemistry platform as a differentiated approach to oligo drug design. Foroohar is positive on Rocket Pharma's lead assets in gene therapies for Fanconi Anemia and Leukocyte Adhesion Deficiency-I "which will likely be the company's first potential approved product." The analyst is positive on Intellia Therapeutics' "robust balance sheet to support development, trading at a material discount to closest comps peers". For Eidos, the analyst cites the prospects of its drug candidate for TTR amyloidosis currently in a placebo-controlled Phase 2 study that may offer a competitive profile relative to Pfizer's (PFE) tafamidis. For Dicerna, Foroohar notes that its DCR-PHXC "is an RNAi therapeutic that targets lactate dehydrogenase A for the treatment of all subtypes of Primary Hyperoxaluria vs. competitor Alnylam's (ALNY) lumasiran, which only treats PH Type 1. For Bluebird Bio, the analyst is positive on its position as a "leader in ex vivo gene therapy, with four programs with visibility towards near-term regulatory approval". Foroohar initiates Avrobio (AVRO), Alnylam (ALNY), and Ionis Pharmaceuticals (IONS) with Market Perform rating based on competitive launches for their products along with "mixed" early signs of their results. The analyst also rates Regenxbio (RGNX) at underperform, saying that its "current valuation more than accounts for robust royalty streams from sales in spinal muscular atrophy" and other partnered assets.
01/17/19
LEER
01/17/19
NO CHANGE
Target $19
LEER
Market Perform
Avrobio price target lowered to $19 from $27 at Leerink
Leerink analyst Mani Foroohar lowered his price target for Avrobio to $19 from $27, while reiterating a Market Perform rating on the shares. While the analyst is positive on recent additions to senior management, he is more conservative on the market opportunity for Fabry gene therapy given the need for higher-intensity preconditioning regimens than the company has used previously, and believes that the potential adoption of value-based annuity pricing models by the industry could pose further risk to Avrobio's bottom line.

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FMCC

Freddie Mac

$0.00

(0.00%)

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GDS

GDS Holdings

$47.16

1.88 (4.15%)

21:00
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BIG

Big Lots

$19.17

-0.75 (-3.77%)

, GCO

Genesco

$36.94

0.38 (1.04%)

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Earnings
Notable companies reporting before tomorrow's open »

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UNVR

Univar

$23.15

0.22 (0.96%)

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PLUG

Plug Power

$3.10

-0.195 (-5.93%)

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RGLD

Royal Gold

$117.91

0.64 (0.55%)

, TECK

Teck Resources

$15.71

-0.11 (-0.70%)

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RGLD

Royal Gold

$117.91

0.64 (0.55%)

TECK

Teck Resources

$15.71

-0.11 (-0.70%)

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IR

Ingersoll-Rand

$128.95

1.405 (1.10%)

19:41
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Upgrade
Ingersoll-Rand rating change at Wells Fargo »

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ICPT

Intercept

$119.86

2.42 (2.06%)

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HUN

Huntsman

$22.34

0.37 (1.68%)

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Huntsman acquires Icynene-Lapolla for all-cash payment of $350M »

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  • 12

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UBER

Uber

$28.65

-0.405 (-1.39%)

18:48
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Uber: Non-consensual kissing of sexual body part reported in 1 in 3M U.S. trips »

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UBER

Uber

$28.65

-0.405 (-1.39%)

18:45
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Hot Stocks
Uber says fatal physical assault reported in 1 in every 122M U.S. trips »

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DOMO

Domo

$19.47

-0.19 (-0.97%)

, EZPW

Ezcorp

$5.21

-0.01 (-0.19%)

18:44
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Hot Stocks
Fly Intel: After Hours Movers »

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DOMO

Domo

$19.47

-0.19 (-0.97%)

EZPW

Ezcorp

$5.21

-0.01 (-0.19%)

DOCU

DocuSign

$69.51

-0.465 (-0.66%)

ULTA

Ulta Beauty

$236.09

-3.27 (-1.37%)

ZUMZ

Zumiez

$30.63

0.67 (2.24%)

CLDR

Cloudera

$10.02

0.16 (1.62%)

MDLA

Medallia

$29.79

0.55 (1.88%)

CRWD

Crowdstrike

$53.00

-2.04 (-3.71%)

AOBC

American Outdoor Brands

$9.42

0.38 (4.20%)

YEXT

Yext

$16.62

0.065 (0.39%)

PD

PagerDuty

$24.99

-0.66 (-2.57%)

SAIC

SAIC

$83.82

-0.57 (-0.68%)

ZM

Zoom Video

$69.73

-0.22 (-0.31%)

KFY

Korn/Ferry

$40.26

0.39 (0.98%)

COO

Cooper Companies

$313.10

1 (0.32%)

GWRE

Guidewire

$119.32

0.68 (0.57%)

OKTA

Okta

$119.18

-2.64 (-2.17%)

UBER

Uber

$28.65

-0.405 (-1.39%)

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UBER

Uber

$28.65

-0.405 (-1.39%)

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Uber says 107 total fatalities in 2017-2018 reported in relation to Uber app »

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UBER

Uber

$28.65

-0.405 (-1.39%)

18:34
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Periodicals
Breaking Periodicals news story on Uber »

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CMG

Chipotle

$819.61

10.12 (1.25%)

18:33
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Chipotle CEO: I took time to understand what makes us unique »

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RCII

Rent-A-Center

$26.02

0.36 (1.40%)

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Rent-A-Center raises quarterly dividend to 29c from 25c per share »

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BKH

Black Hills

$76.66

0.01 (0.01%)

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Black Hills utilities receive approval to upsize Renewable Ready program »

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PRIM

Primoris

$21.92

0.3 (1.39%)

18:02
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Primoris awarded two pipeline contracts for over $45M »

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LMAT

LeMaitre

$35.94

-0.09 (-0.25%)

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LeMaitre CFO sells 121K shares of common stock »

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CLBK

Columbia Financial

$16.33

-0.24 (-1.45%)

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Columbia Financial expands stock buyback to acquire additional 3M shares »

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AXS

Axis Capital

$58.42

0.31 (0.53%)

17:49
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Axis Capital increases quarterly dividend 2.5% to 41c per share »

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  • 26

    Feb

PZZA

Papa John's

$59.67

-0.53 (-0.88%)

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Former Papa John's CEO files suit against ad firm, Bloomberg says »

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  • 11

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THG

Hanover Insurance

$133.80

0.52 (0.39%)

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Hanover Insurance raises dividend to 65c/shr, announces $2.50 special dividend »

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  • 26

    Feb

BHVN

Biohaven Pharmaceutical

$53.79

-0.235 (-0.44%)

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Biohaven Pharmaceutical issued patent relating to troriluzole »

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EPZM

Epizyme

$15.32

-0.48 (-3.04%)

17:45
12/05/19
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Upgrade
Morgan Stanley upgrades Epizyme to Overweight ahead of lymphoma data »

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