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ADXS

Advaxis

$0.45

-0.0499 (-10.04%)

08:07
03/25/19
03/25
08:07
03/25/19
08:07

Advaxis granted U.S. patent relating to Axalimogene Filolisbac

Advaxis announces that the U.S. Patent and Trademark Office has granted patent number 10,189,885 titled "Non-Hemolytic LLO Fusion Proteins and Methods of Utilizing Same." This composition-of-matter patent extends protection for axalimogene filolisbac, or AXAL, through March 2028. Advaxis is in discussions with FDA regarding the partial clinical hold on its Phase 3 AIM2CERV trial and is working to address the questions raised by the Agency surrounding prior AXAL chemistry, manufacturing and controls matters. The FDA did not cite any safety issues related to the trial and all currently enrolled patients are continuing to receive treatment, although no new patients are being enrolled. Advaxis is also in dialogue with FDA to request an amendment to the SPA to include an earlier interim analysis for efficacy.

ADXS Advaxis
$0.45

-0.0499 (-10.04%)

06/13/18
JEFF
06/13/18
DOWNGRADE
Target $2
JEFF
Hold
Advaxis downgraded to Hold from Buy at Jefferies
Jefferies analyst Biren Amin downgraded Advaxis to Hold and cut his price target for the shares to $2 from $9. The analyst prefers to step to the sidelines pending proof-of-concept data. He sees no clear path to partnering for axalimogene filolisbac and notes efficacy data for the ADXS-NEO and ADXS-HOT programs are likely two years away.
06/13/18
06/13/18
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Square (SQ) downgraded to Neutral from Buy at Buckingham with analyst Chris Brendler saying he is taking a "breather" following the year-to-date share outperformance but raised his price target to $65 from $55. 2. Yelp (YELP) downgraded to Sell from Hold at Aegis. 3. AT&T (T) was downgraded to Sell from Neutral at MoffettNathanson while Time Warner (TWX) was downgraded to Neutral from Buy at the firm. Time Warner was also downgraded to Market Perform from Outperform at Barrington. 4. Comcast (CMCSA) downgraded to Market Perform from Outperform at Raymond James. 5. Advaxis (ADXS) downgraded to Hold from Buy at Jefferies. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/12/18
HCWC
09/12/18
NO CHANGE
Target $2
HCWC
Buy
Advaxis price target lowered to $2 from $3 at H.C. Wainwright
H.C. Wainwright analyst Swayampakula Ramakanth lowered his price target for Advaxis to $2 following the company's Q3 results but keeps a Buy rating on the shares. The analyst believes the company has sufficient cash to fund its operations into the second half of 2019, and his new price target reflects expected dilution from the $20M equity raise on September 11.
12/18/18
HCWC
12/18/18
DOWNGRADE
HCWC
Neutral
Advaxis downgraded to Neutral from Buy at H.C. Wainwright
H.C. Wainwright analyst Swayampakula Ramakanth downgraded Advaxis (ADXS) to Neutral without a price target. Amgen's (AMGN) termination of a development and collaboration agreement puts ADXS-NEO in limbo, Ramakanth tells investors in a research note. The analyst believes Amgen's withdrawal has "considerably increased" the development risk on ADXS-NEO and potentially ADXS-HOT as well. He steps to the sidelines "until the viability of the programs can be assured."

TODAY'S FREE FLY STORIES

LULU

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GOLD

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WCC

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NFLX

Netflix

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SGEN

Seattle Genetics

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-3.26 (-2.77%)

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SYBT

S.Y. Bancorp

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DG

Dollar General

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HROW

Harrow Health

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TENB

Tenable Holdings

$24.81

-0.46 (-1.82%)

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TROW

T. Rowe Price

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FTSV

Forty Seven

$30.44

16.04 (111.39%)

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ZS

Zscaler

$47.34

0.62 (1.33%)

, TPR

Tapestry

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0.26 (1.02%)

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ZS

Zscaler

$47.34

0.62 (1.33%)

TPR

Tapestry

$25.80

0.26 (1.02%)

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FRAN

Francesca's

$19.83

1.29 (6.96%)

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Francesca's reports Q3 adj. EPS ($1.12) vs. ($2.08) last year »

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WH

Wyndham Hotels & Resorts

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CNST

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AMGN

Amgen

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NVTA

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ATI

Allegheny Technologies

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ATI

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PTON

Peloton

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VVV

Valvoline

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PCG

PG&E

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  • 07

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LEG

Leggett & Platt

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ADUS

Addus HomeCare

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