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MNLO

Menlo Therapeutics

$7.81

-0.09 (-1.14%)

08:34
03/25/19
03/25
08:34
03/25/19
08:34

Menlo Therapeutics announces publication of Phase 2 serlopitant trial data

Menlo Therapeutics announced the publication of the company's Phase 2 trial of serlopitant for the treatment of pruritus associated with prurigo nodularis, or PN, in the Journal of the American Academy of Dermatology, or JAAD. The previously presented trial results demonstrate that serlopitant reduced pruritus in patients with treatment-refractory PN and was well-tolerated. The study met its primary and multiple secondary efficacy endpoints of pruritus reduction in patients in the serlopitant treatment group compared with placebo. In this randomized, double-blind, placebo-controlled study, 128 patients with chronic, treatment-refractory PN for more than 6 weeks received serlopitant, 5 mg, or placebo orally once daily for 8 weeks. For the primary endpoint assessment, pruritus scores were measured using the average itch visual analog scale. Pruritus scores improved significantly more in patients treated with serlopitant than in patients treated with placebo.

MNLO Menlo Therapeutics
$7.81

-0.09 (-1.14%)

07/24/18
ROTH
07/24/18
INITIATION
Target $29
ROTH
Buy
Menlo Therapeutics initiated with a Buy at Roth Capital
Roth Capital analyst Yasmeen Rahimi started Menlo Therapeutics with a Buy rating and $29 price target. The analyst cited the company's Phase 3 asset serlopitant for prurigo nodularis, with significant upside potential from Phase 2 programs in psoriasis-related pruritus and refractory chronic cough.
09/06/18
CANT
09/06/18
INITIATION
Target $25
CANT
Overweight
Menlo Therapeutics initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Louise Chen initiated Menlo Therapeutics with an Overweight and $25 price target.
09/06/18
CANT
09/06/18
INITIATION
Target $25
CANT
Overweight
Cantor sees positive data driving Menlo shares higher, starts at Overweight
Cantor Fitzgerald analyst Louise Chen initiated coverage of Menlo Therapeutics with an Overweight rating and $25 price target. The analyst expects pipeline success to drive consensus earnings estimates and the stock higher. Chen believes a "positive, steady stream of pivotal data readouts" for Nularis, Tussix and Psorixa will begin in Q4 of this year.
10/09/18
JEFF
10/09/18
NO CHANGE
Target $7
JEFF
Hold
Menlo Therapeutics price target lowered to $7 from $9 at Jefferies
Jefferies analyst David Steinberg lowered his price target for Menlo Therapeutics to $7 after the company said it will halt serlopitant development in chronic cough with the Phase 2 study failing to meet its endpoints. This marks the second clinical failure this year, but the rest of the program continues on post the prior Phase 2 success in prurigo nodularis and chronic pruritus, Steinberg tells investors in a research note. The analyst keeps a Hold rating on Menlo Therapeutics.

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