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XERS

Xeris Pharmaceuticals

$9.75

-0.36 (-3.56%)

08:51
03/25/19
03/25
08:51
03/25/19
08:51

Xeris Pharmaceuticals presents new data on developmental RTU glucagon

Xeris Pharmaceuticals announced it is presenting data on its developmental ready-to-use room-temperature stable liquid glucagon at two medical conferences. Xeris will present the first data from its Phase 2 study of RTU, room-temperature stable liquid glucagon for congenital hyperinsulinemia during ENDO 2019. As part of this randomized, placebo-controlled study, five patients with CHI under 1 year of age were enrolled to receive Xeris' RTU glucagon delivered continuously through an Omnipod infusion pump to prevent hypoglycemia and to lower supplemental glucose requirements, via reductions in intravenous glucose infusion rates. The company said, "Treated patients had a positive clinical response compared to those receiving placebo, and follow-up open-label treatment resulted in a clinically meaningful response in all evaluable patients." Results of a Xeris budget impact model on the estimated potential reduction in costs associated with use of its RTU room-temperature stable liquid glucagon will be presented in a poster during the Academy of Managed Care Pharmacy's AMCP Managed Care & Specialty Pharmacy Annual Meeting. The model was developed to estimate the economic impact of open coverage of Gvoke HypoPen for the treatment of severe hypoglycemia events as an alternative to currently marketed glucagon emergency kits . The company said, "With its positive functional efficacy profile, the results of the model illustrate the potential financial benefits for open coverage of glucagon rescue pen. The health utilization data also supports physicians to increase patient access to completed and filled glucagon prescriptions, in order to optimize patient outcomes. Results of the analysis indicate that significant overall cost savings may be achieved with use of the Xeris GRP." A New Drug Application for Xeris' lead product candidate, Gvoke HypoPen for the treatment of severe hypoglycemia, is currently under review with the U.S. Food and Drug Administration, with a decision expected during Q2.

  • 10

    Jun

XERS Xeris Pharmaceuticals
$9.75

-0.36 (-3.56%)

07/16/18
JEFF
07/16/18
INITIATION
Target $23
JEFF
Buy
Xeris Pharmaceuticals initiated with a Buy at Jefferies
Jefferies analyst David Steinberg started Xeris Pharmaceuticals with a Buy rating and $23 price target. The company's "derisked" lead asset, with its new drug application to be filed in Q3, is a ready-to-use liquid glucagon autoinjector for emergency hypoglycemia that could help replace the "cumbersome" current standard of care, Steinberg tells investors in a research note. The Xeris pen could generate peak sales of $400M, the analyst estimates.
07/16/18
MZHO
07/16/18
INITIATION
Target $26
MZHO
Buy
Xeris Pharmaceuticals initiated with a Buy at Mizuho
Mizuho initiated Xeris Pharmaceuticals with a Buy and $26 price target.
07/17/18
MZHO
07/17/18
INITIATION
Target $26
MZHO
Buy
Mizuho starts Xeris Pharmaceuticals with Buy rating, $26 target
Mizuho analyst Difei Yang last night initiated coverage of Xeris Pharmaceuticals with a Buy rating and $26 price target. The company offers a potentially superior solution for the treatment of severe hypoglycemia compared to the standard of care - Eli Lilly's (LLY) glucagon emergency kit, Yang told investors in a research note. The analyst sees a "significant growth opportunity" for the ready-to-use glucagon rescue pen as more healthcare professionals prescribe an easier option for patients with diabetes at risk of severe hypoglycemia.
09/13/18
EAMC
09/13/18
INITIATION
Target $10
EAMC
Sell
Xeris Pharmaceuticals initiated with a Sell at Empire
Empire analyst Dr. Cathey Reese initiated Xeris Pharmaceuticals with a Sell and $10 price target saying its main pipeline product is a stable liquid glucagon in an autoinjector device, which the company filed for an FDA approval in mid-August-2018. Reese said several competitor pipelines, including Eli Lilly's (LLY), are in development for stable liquid glucagon products and the likely approval of Lilly's nasal spray glucagon should make it difficult for Xeris to reach investors' revenue expectations.

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