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SRPT

Sarepta

$118.22

-5.78 (-4.66%)

13:15
03/25/19
03/25
13:15
03/25/19
13:15

Piper stays bullish on Sarepta, says CK spikes 'not worrisome'

Piper Jaffray analyst Danielle Brill reiterates an Overweight rating on Sarepta Therapeutics provided a nine-month update for all four patients in its Phase 1 microdystrophin gene therapy trial. Results showed "marked improvements" in the NorthStar Ambulatory Assessment for all patients while creatine kinase level spikes were also observed, Brill tells investors in a research note. The analyst attributes the CK spikes to spikes to physical exertion and finds them "not worrisome." CK levels trended down for patients and the functional data continue to look encouraging, Brill contends. She stays bullish on Sarepta shares. The stock in afternoon trading is down 2%, or $2.99, to $119.27.

  • 25

    Mar

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    Aug

SRPT Sarepta
$118.22

-5.78 (-4.66%)

03/25/19
HCWC
03/25/19
NO CHANGE
Target $267
HCWC
Buy
Sarepta data bode well for registration study, says H.C. Wainwright
The functional gains with Sarepta Therapeutics' SRP-9001 in this morning's data bode well for the registration study, H.C. Wainwright analyst Debjit Chattopadhyay tells investors in a research note. Micro-dystrophin gene therapy appears to positively impact key functional endpoints with a 34% increase in NSAA scores, and a -20%, -29%, and -13% change in time to rise, four-minute stair climb, and time to 100 meters, respectively from baseline to day 270, says the analyst. While bears are likely to point to the large variability in CK, a 64% decline from baseline, while not quite the 90%-plus at an earlier time point, for a measurement that is uniquely susceptible to activity is more an attribute of increased functional capacity as opposed to waning of gene therapy's effectiveness hypothesis in the younger patients, contends Chattopadhyay. He has a Buy rating on Sarepta with a $267 price target.
03/25/19
JPMS
03/25/19
NO CHANGE
JPMS
Overweight
Data today reinforce Sarepta's 'pole position,' says JPMorgan
The updated data from the first four Duchenne muscular dystrophy patients of Sarepta Therapeutics' Phase 1/2 trial at nine months are "all directionally positive" on both biomarker and functional assessments, JPMorgan analyst Anupam Rama tells investors in a research note. The analyst is not surprised with the creatine kinase fluctuations as patients become more active and finds it important that all biomarker/functional endpoints were improved from baseline at nine months. While lingering questions about competition in the micro-dystrophin space remain, these data reinforce Sarepta's "pole position," Rama contends. He keeps an Overweight rating on the shares. The stock in morning trading is down 4%, or $4.53, to $117.73.
03/25/19
RBCM
03/25/19
NO CHANGE
Target $192
RBCM
Outperform
Sarepta data does not change thesis on DMD program, says RBC Capital
RBC Capital analyst Brian Abrahams notes that Sarepta Theraputics this morning reported nine-month functional and creatine kinase data from baseline from the four patients in the Phase 1 open-label study of the company's micro-dystrophin gene therapy candidate for Duchenne muscular dystrophy. Overall, Abrahams says the results show continued improvements in North Star Ambulatory Assessment functional scores vs. the baseline, and that while the update may not stop concerns, it does not change his overall thesis on the program, where he continues to believe the totality of expression, biomarker and functional data point to real benefits that should enable improvements supporting approval in ongoing/subsequent studies. Abrahams, who has an Outperform rating and $192 price target on Sarepta, says he would use weakness as a buying opportunity.
03/25/19
NEED
03/25/19
NO CHANGE
Target $196
NEED
Buy
Sarepta treatment shows 'impressive' improvement at 9 months, says Needham
After Sarepta presented updated 9 month data from four boys in a study testing their micro-dystrophin gene therapy, Needham analyst Chad Messer said "impressive" functional improvement was observed in all four patients and that levels of creatinine kinase, which is a measure of muscle damage, were generally improved and below levels normally associated with Duchenne. Messer maintains a Buy rating and $196 price target on Sarepta shares.

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AT&T

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AEO

American Eagle

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SAGE

Sage Therapeutics

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$0.00

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PMT

PennyMac Mortgage

$22.75

-0.055 (-0.24%)

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SALM

Salem Media

$1.49

0.03 (2.05%)

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HROW

Harrow Health

$6.74

0.21 (3.22%)

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ZUMZ

Zumiez

$34.02

-0.67 (-1.93%)

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Zumiez director sells 5.8K shares of common stock »

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TRC

Tejon Ranch

$16.07

0.02 (0.12%)

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EXTR

Extreme Networks

$6.89

0.02 (0.29%)

, AVGO

Broadcom

$315.10

0.61 (0.19%)

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$315.10

0.61 (0.19%)

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WDFC

WD-40

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ASPU

Aspen Group

$7.00

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Netflix

$293.21

-9.27 (-3.06%)

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Uber

$27.89

0.18 (0.65%)

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$145.73

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UBS

UBS

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XP

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