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PBYI

Puma Biotechnology

$38.69

-0.35 (-0.90%)

08:05
04/01/19
04/01
08:05
04/01/19
08:05

Puma Biotechnology, Pierre Fabre enter into license agreement

Puma Biotechnology and Pierre Fabre have entered into an exclusive license agreement under which Pierre Fabre will develop and commercialize NERLYNX within Europe and part of Africa. In September 2018 the European Commission granted marketing authorization for NERLYNX for the extended adjuvant treatment of adult patients with early stage hormone receptor positive HER2-overexpressed/amplified breast cancer and who are less than one year from the completion of prior adjuvant trastuzumab-based therapy. Under the terms of the agreement, Puma will receive an upfront payment of $60M, as well as additional regulatory and commercial milestone payments totaling up to $345M. In addition, Puma will receive significant double-digit royalties on NERLYNX sales throughout the territory covered by the license agreement between Puma and Pierre Fabre.

PBYI Puma Biotechnology
$38.69

-0.35 (-0.90%)

12/18/18
RBCM
12/18/18
NO CHANGE
Target $29
RBCM
Sector Perform
Puma Biotechnology price target raised to $29 from $26 at RBC Capital
RBC Capital analyst Kennen MacKay raised his price target on Puma Biotechnology to $29 after its release of a positive phase 3 NALA trial data which "could establish Nerlynx as Standard of Care in 3L+ metastatic HER2+ breast cancer on paper". The analyst also keeps his Sector Perform rating on the shares, adding that the "commercial uptake" for the program remains a "concern" amid the changes in Standard of Care model to off-label therapies, which he says should keep the stock as a "show me" story.
01/03/19
GUGG
01/03/19
DOWNGRADE
GUGG
Neutral
Puma Biotechnology downgraded to Neutral from Buy at Guggenheim
01/17/19
LEER
01/17/19
INITIATION
Target $21
LEER
Market Perform
Puma Biotechnology initiated with a Market Perform at Leerink
Leerink analyst Thomas Smith started Puma Biotechnology with a Market Perform rating and $21 price target. In the near-term, the analyst sees the shares trading based on the outlook for Nerlynx revenue in its currently approved indication, extended adjuvant therapy after adjuvant Herceptin, and prospects for uptake in a near-term expansion indication, metastatic breast cancer. Results in Q3 were disappointing, he notes, further deflating investor sentiment as sales growth slowed and the number of company-reported active patients on therapy was revised lower. However, shares are trading in-line with his below consensus estimates and at current levels he cannot rule out strategic interest, given the resurgence in oncology-focused M&A and scarcity of commercial-stage oncology assets.
03/01/19
SBSH
03/01/19
NO CHANGE
Target $70
SBSH
Buy
'Excuses' for not owning Puma Biotechnology 'rapidly shrinking,' says Citi
With Puma Biotechnology's U.S. Nerlynx sales shaping up at $300M in 2019, U.S. metastatic revenue coming in 2020, Europe launching in the first half of 2019 and rest-of-world territories with high royalties coming online in next 12-24 months, the Nerlynx brand is closing in on the $500M mark "faster than many investors may appreciate," Citi analyst Yigal Nochomovitz tells investors in a research note. The "list of excuses for not owning the launch now seems to be rapidly shrinking," adds the analyst after Puma reported Q4 results. He raised his price target for the shares to $70 from $67 and keeps a Buy rating on the shares.

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PEGI

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