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PFE

Pfizer

$42.63

-0.24 (-0.56%)

14:58
04/04/19
04/04
14:58
04/04/19
14:58

Pfizer says FDA approves sNDA to expand indications for IBRANCE

Pfizer announced that the U.S. Food and Drug Administration approved a supplemental New Drug Application to expand the indications for IBRANCE in combination with an aromatase inhibitor or fulvestrant to include men with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer. The approval is based on data from electronic health records and postmarketing reports of the real-world use of IBRANCE in male patients sourced from three databases: IQVIA Insurance database, Flatiron Health Breast Cancer database and the Pfizer global safety database. "With this approval, we are now able to offer IBRANCE to the underserved male breast cancer community and provide more patients with HR+, HER2- metastatic breast cancer the opportunity to access an innovative medicine," said Chris Boshoff, M.D., Ph.D., Chief Development Officer, Oncology, Pfizer Global Product Development. "We appreciate that our partnership with the FDA has allowed us to take a significant step forward in the use of real-world data to bring medicines to patients who are most in need."

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PFE Pfizer
$42.63

-0.24 (-0.56%)

01/31/19
01/31/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pfizer (PFE) upgraded to Outperform from Neutral at Credit Suisse and to Buy from Hold at Argus. 2. Tiffany (TIF) upgraded to Overweight from Neutral at Atlantic Equities with analyst Daniela Nedialkova saying the pullback has been largely driven by macro concerns while fundamentals of the brand are strong and preliminary FY19 guidance is conservative. 3. Scotts Miracle-Gro (SMG) upgraded to Neutral from Underweight at JPMorgan with analyst Jeffrey Zekauskas citing valuation. 4. Geron (GERN) upgraded to Buy from Neutral at B. Riley FBR with analyst George Zavoico saying he believes investors should focus on the pivotal Phase III trial of imetelstat. 5. Ralph Lauren (RL) upgraded to Outperform from Market Perform at Telsey Advisory with analyst Dana Telsey saying the company's improving sakes, combined with ongoing margin expansion, should bolster its earnings. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
02/20/19
SBSH
02/20/19
UPGRADE
Target $41
SBSH
Neutral
Pfizer resumed with a Neutral from Sell at Citi
Citi analyst Andrew Baum resumed coverage of Pfizer following a period of restriction and upgraded the shares to Neutral from Sell. He also boosted his price target for the shares to $41 from $37. The analyst says the recent pullback in the stock, along with the 5%-8% 2019-2021 consensus estimate reductions, gives him the opportunity to close his Sell rating. He believes management action on business development, cost saving or moves to better monetize Pfizer's Established Product business are likely near-term drivers of the stock.
02/20/19
02/20/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pfizer (PFE) resumed with a Neutral from Sell at Citi with analyst Andrew Baum saying the recent pullback in the stock, along with the 5%-8% 2019-2021 consensus estimate reductions, gives him the opportunity to close his Sell rating. 2. Transocean (RIG) and Diamond Offshore (DO) were upgraded to Overweight from Underweight at Barclays. 3. American Axle (AXL) upgraded to Buy from Neutral at BofA/Merrill with analyst John Murphy citing progress with restructuring, GM's (GM) truck cycle, and balance sheet deleveraging. 4. Credit Suisse (CS) upgraded to Hold from Sell at Berenberg. 5. Ipsen (IPSEY) upgraded to Neutral from Sell at Goldman Sachs with analyst Diana Na citing valuation. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
02/26/19
LEHM
02/26/19
NO CHANGE
LEHM
Galapagos weakness could be tied to Pfizer safety alert, says Barclays
Barclays believes the weakness today in Galapagos NV (GLPG) could be attributed to, at least in part, the FDA's safety communication on Pfizer's (PFE) post-marketing study of 10mg daily Xeljanz. Competitor safety issues with higher dose JAK inhibitors was a major focus of Galapagos' post-earnings conference call last week, Barclays tells investors in a research note. Galapagos management, while limited in what it can say pending the data, seems to believe they can get both doses approved, Barclays contends. Further, the firm points out that the company has received no communication and sees no reason to conclude that the FDA has determined that thromboembolic events are a class effect of the JAKs. Shares of Galapagos are down 1.5%, or $1.45, to $97.28 in late morning trading.

TODAY'S FREE FLY STORIES

SGEN

Seattle Genetics

$71.10

1.69 (2.43%)

21:00
04/25/19
04/25
21:00
04/25/19
21:00
Recommendations
Seattle Genetics analyst commentary at Piper Jaffray »

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TCBK

TriCo Bancshares

$39.57

-0.47 (-1.17%)

20:35
04/25/19
04/25
20:35
04/25/19
20:35
Earnings
TriCo Bancshares reports Q1 EPS 74c, consensus 71c »

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XOM

Exxon Mobil

$82.25

0.51 (0.62%)

, CVX

Chevron

$117.93

-0.38 (-0.32%)

20:25
04/25/19
04/25
20:25
04/25/19
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

XOM

Exxon Mobil

$82.25

0.51 (0.62%)

CVX

Chevron

$117.93

-0.38 (-0.32%)

CL

Colgate-Palmolive

$68.64

-0.2 (-0.29%)

ADM

Archer Daniels

$41.77

-0.99 (-2.32%)

WY

Weyerhaeuser

$26.27

-0.07 (-0.27%)

AAL

American Airlines

$33.36

-0.64 (-1.88%)

LEA

Lear

$146.64

-6.455 (-4.22%)

IPG

Interpublic Group

$22.28

-0.26 (-1.15%)

GT

Goodyear Tire

$19.56

-0.54 (-2.69%)

AN

AutoNation

$39.43

0.91 (2.36%)

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ATRC

AtriCure

$28.19

0.21 (0.75%)

20:18
04/25/19
04/25
20:18
04/25/19
20:18
Recommendations
AtriCure analyst commentary at Piper Jaffray »

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NOW

ServiceNow

$260.95

18.54 (7.65%)

19:43
04/25/19
04/25
19:43
04/25/19
19:43
Recommendations
ServiceNow analyst commentary at Jefferies »

ServiceNow price target…

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GFI

Gold Fields

$3.74

0.08 (2.19%)

19:34
04/25/19
04/25
19:34
04/25/19
19:34
Upgrade
Gold Fields rating change at BMO Capital »

Gold Fields upgraded to…

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AMZN

Amazon.com

$1,902.53

1.81 (0.10%)

19:28
04/25/19
04/25
19:28
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19:28
Hot Stocks
Watchdog finds at least 78,000 reviews removed from Amazon »

Watchdog Which? said that…

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EHTH

eHealth

$62.23

0.32 (0.52%)

, MAT

Mattel

$12.30

-0.25 (-1.99%)

19:02
04/25/19
04/25
19:02
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19:02
Hot Stocks
Fly Intel: After Hours Movers »

UP AFTER EARNINGS: …

EHTH

eHealth

$62.23

0.32 (0.52%)

MAT

Mattel

$12.30

-0.25 (-1.99%)

KNL

Knoll

$20.57

-0.22 (-1.06%)

GRUB

GrubHub

$69.83

0.53 (0.76%)

PRO

Pros Holdings

$45.06

-0.25 (-0.55%)

F

Ford

$9.41

-0.17 (-1.77%)

COF

Capital One

$88.09

0.3 (0.34%)

SFLY

Shutterfly

$42.30

-0.65 (-1.51%)

COLM

Columbia Sportswear

$104.45

-0.65 (-0.62%)

SWN

Southwestern Energy

$4.03

-0.13 (-3.13%)

DFS

Discover

$77.48

0.43 (0.56%)

LOGM

LogMeln

$84.32

0.085 (0.10%)

BABY

Natus Medical

$25.20

0.54 (2.19%)

AMZN

Amazon.com

$1,902.53

1.81 (0.10%)

TMUS

T-Mobile

$72.68

-0.67 (-0.91%)

SBUX

Starbucks

$77.07

0.65 (0.85%)

ATEN

A10 Networks

$7.28

0.14 (1.96%)

PFPT

Proofpoint

$131.35

3.56 (2.79%)

FII

Federated Investors

$33.57

0.605 (1.84%)

INTC

Intel

$57.59

-1.13 (-1.92%)

BEAT

BioTelemetry

$59.26

0.52 (0.89%)

BGG

Briggs & Stratton

$13.61

-0.44 (-3.13%)

SKYW

SkyWest

$58.44

-1.31 (-2.19%)

SGEN

Seattle Genetics

$71.10

1.69 (2.43%)

VCRA

Vocera

$31.31

0.36 (1.16%)

ILMN

Illumina

$318.91

4.47 (1.42%)

INT

World Fuel Services

$31.15

0.1 (0.32%)

BMRN

BioMarin

$85.40

-0.06 (-0.07%)

MHK

Mohawk

$130.69

-3.46 (-2.58%)

03/08/13
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ATEN

A10 Networks

$7.28

0.14 (1.96%)

19:00
04/25/19
04/25
19:00
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19:00
Earnings
A10 Networks sees Q2 EPS (8c) to 0c, two estimates 0c »

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ATEN

A10 Networks

$7.28

0.14 (1.96%)

18:59
04/25/19
04/25
18:59
04/25/19
18:59
Earnings
A10 Networks reports Q1 EPS (9c), two estimates (7c) »

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CNC

Centene

$50.20

0.04 (0.08%)

18:44
04/25/19
04/25
18:44
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18:44
Hot Stocks
Centene CEO: Most people are happy with their healthcare »

In an interview on…

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APHA

Aphria

$7.64

-0.17 (-2.18%)

18:23
04/25/19
04/25
18:23
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18:23
Hot Stocks
Green Growth Brands says offer for Aphria has expired »

Green Growth Brands…

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ALGN

Align Technology

$296.77

-0.35 (-0.12%)

18:21
04/25/19
04/25
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18:21
Hot Stocks
Align Technology CEO: We are enjoying good growth in North America »

In an interview on…

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AAPL

Apple

$205.28

-1.82 (-0.88%)

18:21
04/25/19
04/25
18:21
04/25/19
18:21
Periodicals
Several veterans leave Apple's design team, WSJ reports »

Apple's design team…

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FB

Facebook

$193.23

10.59 (5.80%)

18:18
04/25/19
04/25
18:18
04/25/19
18:18
Hot Stocks
Canadian agency says probe shows Facebook broke privacy law »

Canada's Office of…

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NOV

National Oilwell

$26.44

-0.04 (-0.15%)

18:17
04/25/19
04/25
18:17
04/25/19
18:17
Earnings
National Oilwell reports Q1 EPS (20c), consensus (8c) »

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FB

Facebook

$193.23

10.59 (5.80%)

18:16
04/25/19
04/25
18:16
04/25/19
18:16
Hot Stocks
Ireland's DPC opens statutory inquiry into Facebook »

Ireland's Data…

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FB

Facebook

$193.23

10.59 (5.80%)

18:15
04/25/19
04/25
18:15
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18:15
Hot Stocks
NY AG to investigate Facebook's collection of user email contact databases »

New York State Attorney…

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AMZN

Amazon.com

$1,902.53

1.81 (0.10%)

18:09
04/25/19
04/25
18:09
04/25/19
18:09
Hot Stocks
Amazon.com says had 'a lot of good customer wins' in Q1 »

Says: Usage growth higher…

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FIBK

First Interstate

$41.94

-0.63 (-1.48%)

18:08
04/25/19
04/25
18:08
04/25/19
18:08
Earnings
First Interstate reports Q1 EPS 69c, consensus 72c »

Reports Q1 provision for…

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F

Ford

$9.41

-0.17 (-1.77%)

18:03
04/25/19
04/25
18:03
04/25/19
18:03
Hot Stocks
Breaking Hot Stocks news story on Ford »

Ford says improving…

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PUB

People's Utah Bancorp

$28.02

0.09 (0.32%)

18:01
04/25/19
04/25
18:01
04/25/19
18:01
Earnings
People's Utah Bancorp reports Q1 EPS ,55c consensus 55c »

Reports Q1 NII $26.91M,…

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AEGN

Aegion

$19.44

-0.58 (-2.90%)

17:57
04/25/19
04/25
17:57
04/25/19
17:57
Hot Stocks
Aegion subsidiary awarded three contracts valued at $13M total »

Aegion announced that its…

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  • 02

    May

AMZN

Amazon.com

$1,902.53

1.81 (0.10%)

17:55
04/25/19
04/25
17:55
04/25/19
17:55
Hot Stocks
Amazon.com says will spend $800M in Q2 to move to one-day Prime delivery »

Says: Need to build out…

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F

Ford

$9.41

-0.17 (-1.77%)

17:53
04/25/19
04/25
17:53
04/25/19
17:53
Hot Stocks
Ford CFO: Encouraged by progress made in China toward return to profitability »

Sees FY19 revenue growth,…

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