Breaking News Instant updates and real-time market news.

MDGL

Madrigal Pharmaceuticals

$132.67 /

-2.04 (-1.51%)

06:53
04/08/19
04/08
06:53
04/08/19
06:53

Madrigal Pharmaceuticals to present additional data from Phase 2 NASH study

Madrigal Pharmaceuticals announced that on Thursday, April 11, at the International Liver Congress 2019, European Association for the Study of the Liver in Vienna, further in depth analyses of the Phase 2 NASH study with MGL-3196 will be presented. Resmetirom is currently in Phase 3 development for the treatment of NASH patients with stage 2-3 fibrosis. MGL-3196-05 was a 36-week multicenter, randomized, double-blind, placebo- controlled serial MRI-PDFF, paired liver biopsy study in adults with biopsy-confirmed NASH and hepatic fat fraction greater than or equal to10%. In 12 week interim and 36 week final analyses, MGL-3196 treated patients had significantly more reduction of liver fat compared with placebo on MRI-PDFF and up to 77% of resmetirom-treated patients showed at least a 30% reduction of liver fat. NASH resolution was attained on biopsy in 39% of resmetirom patients who had a positive PDFF response. At 36 weeks 107 paired biopsies were assessed to examine the predictive power of PDFF response on histologic response of NAS, NASH resolution and reduction of ALT. In resmetirom-treated patients, a 12 week PDFF response versus non-response was predictive of NASH resolution at week 36 and correlated with improvements in steatosis, hepatocyte ballooning and inflammation as well as reduction in ALT. Placebo patients with weight loss greater than or equal to5% were likely PDFF responders, and a PDFF response in placebo patients also predicted reductions in inflammation and hepatocyte ballooning. Dr. Harrison stated, "These analyses show that positive MRI-PDFF responses correlate with reductions in hepatocyte ballooning, inflammation and NASH resolution on liver biopsy and are associated with decreases in ALT. The data suggest that reduction of hepatic fat is a critical component of NASH improvement and resolution."

  • 12

    Apr

MDGL Madrigal Pharmaceuticals
$132.67 /

-2.04 (-1.51%)

03/28/19 UBS
Madrigal Pharmaceuticals price target raised to $143 from $119 at UBS
02/28/19 H.C. Wainwright
Madrigal price target lowered to $228 from $313 at H.C. Wainwright
01/23/19 UBS
Madrigal Pharmaceuticals initiated with a Neutral at UBS
12/14/18 Wolfe Research
Madrigal Pharmaceuticals initiated with an Outperform at Wolfe Research

TODAY'S FREE FLY STORIES

Hot Stocks
AbbVie says Phase 3 trial of venetoclax combo did not meet primary endpoint » 18:57
02/28/20
02/28
18:57
02/28/20
18:57
ABBV

AbbVie

$85.27 /

-0.065 (-0.08%)

AbbVie announced the…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Invitation Homes cancels participation at Citi Global Property CEO Conference » 18:32
02/28/20
02/28
18:32
02/28/20
18:32
INVH

Invitation Homes

$28.65 /

-0.29 (-1.00%)

Invitation Homes…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Hudson Pacific cancels presentation at Citi 2020 Global Property CEO Conference » 18:31
02/28/20
02/28
18:31
02/28/20
18:31
HPP

Hudson Pacific

$32.26 /

-1.15 (-3.44%)

Hudson Pacific Properties…

Hudson Pacific Properties announced the cancellation of the company's presentation and webcast at Citi's 2020 Global Property CEO Conference, previously scheduled to take place on Tuesday, March 3, at 11:00 a.m. ET. Management no longer plans to attend the conference in light of a growing list of cancellations.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Syndicate
CatchMark Timber files $600M mixed securities shelf  18:25
02/28/20
02/28
18:25
02/28/20
18:25
CTT

CatchMark Timber

$9.17 /

-0.48 (-4.97%)

 
ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Syndicate
Westwater Resources files $50M mixed securities shelf  18:24
02/28/20
02/28
18:24
02/28/20
18:24
WWR

Westwater Resources

$1.77 /

+0.05 (+2.91%)

 
Hot Stocks
Clean Harbors CEO: We have a good year ahead of us » 18:23
02/28/20
02/28
18:23
02/28/20
18:23
CLH

Clean Harbors

$69.16 /

-3.69 (-5.07%)

In an interview on…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
Teladoc to host investor day » 17:56
02/28/20
02/28
17:56
02/28/20
17:56
TDOC

Teladoc

$124.79 /

-10.38 (-7.68%)

Investor Day to be held…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
General Electric to hold a conference call » 17:52
02/28/20
02/28
17:52
02/28/20
17:52
GE

General Electric

$10.83 /

+0.45 (+4.34%)

Management holds an…

Management holds an investor outlook conference call on March 4 at 8 am. Webcast Link

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
Centene to host conference call » 17:49
02/28/20
02/28
17:49
02/28/20
17:49
CNC

Centene

$52.90 /

+0.27 (+0.51%)

Chairman & CEO…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Wolverine World Wide's Jeppesen sells 45,493 common shares » 17:49
02/28/20
02/28
17:49
02/28/20
17:49
WWW

Wolverine World Wide

$26.34 /

-0.55 (-2.05%)

In a regulatory filing,…

In a regulatory filing, Wolverine World Wide's president of Global Operations and Heritage Groups Michael Jeppesen disclosed the sale of 45,493 common shares of the company on February 27 at a price of $27.65 per share.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Syndicate
Westwater Resources files to sell 1M shares of common stock for holders  17:48
02/28/20
02/28
17:48
02/28/20
17:48
WWR

Westwater Resources

$1.77 /

+0.05 (+2.91%)

 
Periodicals
United Airlines to delay investor day set for March 5, Bloomberg says » 17:42
02/28/20
02/28
17:42
02/28/20
17:42
UAL

United Airlines

$61.42 /

-3.58 (-5.51%)

United Airlines has…

United Airlines has delayed its investor day, which was originally planned for March 5, to September, citing the coronavirus outbreak, Bloomberg reports.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Syndicate
Mondelez files automatic mixed securities shelf  17:40
02/28/20
02/28
17:40
02/28/20
17:40
MDLZ

Mondelez

$52.83 /

-1.61 (-2.96%)

 
ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
FDA approves GSK's Advil Dual Action with Acetaminophen for OTC use » 17:39
02/28/20
02/28
17:39
02/28/20
17:39
GSK

GlaxoSmithKline

$40.51 /

-1.07 (-2.57%)

GlaxoSmithKline announced…

GlaxoSmithKline announced that the U.S. Food and Drug Administration has approved Advil Dual Action with Acetaminophen as an over-the-counter product for pain relief. The exclusive formula is now the first FDA-approved OTC combination of ibuprofen and acetaminophen in the United States and will be available over-the-counter nationwide in 2020. Franck Riot, Head of R&D, GSK Consumer Healthcare said: "For decades, many consumers have been using ibuprofen and acetaminophen to get the benefits of both active ingredients when safely treating their headaches, muscle aches, backaches, arthritis and other joint pain. Now Advil, the No. 1 selling OTC pain reliever, will offer US consumers the first-ever alternative option -- a single, fixed-dose combination pain reliever. As the world-leader in pain relief, Advil Dual Action and our recently FDA-approved Voltaren Arthritis Pain gel, demonstrates GSK's commitment to providing new safe, effective and convenient pain relief options for consumers."

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Syndicate
Radian Group files automatic mixed securities shelf  17:37
02/28/20
02/28
17:37
02/28/20
17:37
RDN

Radian Group

$21.24 /

-0.495 (-2.28%)

 
ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Lockheed Martin Comments awarded $141.66M Navy contract modification » 17:35
02/28/20
02/28
17:35
02/28/20
17:35
LMT

Lockheed Martin

$369.93 /

-9.89 (-2.60%)

Lockheed Martin was…

Lockheed Martin was awarded a $141.66M modification to a previously awarded fixed-price-incentive-firm-target contract. This modification provides for the stand-up of organic level repair capabilities for the combat aircraft F-35 communications, navigation and information system. Work is expected to be completed by June 2024. FY19 aircraft procurement funds in the amount of $70.83M, FY19 aircraft procurement funds in the amount of $35.41M and FY19 aircraft procurement funds in the amount of $35.41M will be obligated at time of award, none of which will expire at the end of the current fiscal year. The Naval Air Systems Command is the contracting activity.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Bell-Boeing awarded $165.28M Navy contract modification » 17:28
02/28/20
02/28
17:28
02/28/20
17:28
BA

Boeing

$275.23 /

-12.87 (-4.47%)

Bell-Boeing was awarded a…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Periodicals
General Motors to hire 1,200 new workers for Michigan plants, Bloomberg reports » 17:27
02/28/20
02/28
17:27
02/28/20
17:27
GM

General Motors

$30.48 /

-0.23 (-0.75%)

General Motors announced…

General Motors announced it will hire 1,200 new workers for its two plants in Lansing, Michigan, partly due to rising demand for the company's mid-sized sport utility vehicles, Bloomberg's David Welch reports. The company plans to add a third shift and 800 workers at its Lansing Delta Township plant, where it builds the Chevrolet Traverse and Buick Enclave SUVs. GM also will institute a second shift, including 400 new hires, at its Lansing Grand River factory. That facility makes the Chevy Camaro sports car and the all-new Cadillac CT4 and CT5 sedans. Reference Link

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Periodicals
Walmart names Iannone COO for U.S. e-commerce, Bloomberg says » 17:24
02/28/20
02/28
17:24
02/28/20
17:24
WMT

Walmart

$107.68 /

-2.67 (-2.42%)

Walmart has appointed…

Walmart has appointed Jamie Iannone as its COO for U.S. e-commerce, Bloomberg's Matthew Boyle reports. Iannone, who joined the retailer in 2014, was previously heading hte web, membership, and marketing operations of Sam's Club, Boyle says, citing a memo. At Sam's Club, who led several initiatives to improve customer service and increase online sales, the author notes. Reference Link

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Northrop Grumman awarded $262.28M Air Force contract modification » 17:24
02/28/20
02/28
17:24
02/28/20
17:24
NOC

Northrop Grumman

$328.32 /

-3.26 (-0.98%)

Northrop Grumman has been…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Vectrus awarded $121.78M Army contract modification » 17:20
02/28/20
02/28
17:20
02/28/20
17:20
VEC

Vectrus

$51.96 /

-0.34 (-0.65%)

Vectrus was awarded a…

Vectrus was awarded a $121.78M modification to a contract for continued support of critical operation, maintenance and defense of Army communications. Work will be performed in Kuwait, with an estimated completion date of August 28. FY20 operations and maintenance funds in the amount of $121.78M were obligated at the time of the award. U.S. Army Contracting Command is the contracting activity.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Chesapeake Granite announces NYSE determination to suspend trading of its units » 17:12
02/28/20
02/28
17:12
02/28/20
17:12
CHKR

Chesapeake Granite

$0.58 /

-0.0448 (-7.15%)

Chesapeake Granite…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

Earnings
New Oriental Education cuts Q3 revenue view to $902.1M-$933.2M » 17:05
02/28/20
02/28
17:05
02/28/20
17:05
EDU

New Oriental Education

$128.27 /

-4.43 (-3.34%)

Q3 consensus $998.56M.…

Q3 consensus $998.56M. The company previously announced its outlook which estimated the total net revenues for the third quarter to be in the range of $983M-$1.006B, representing year-over-year growth in the range of 23%-26%. The weaker-than-expected revenues are mainly due to the impact of the outbreak of coronavirus in China, which was significantly offset by measures taken by the company to effectively move its offline classes to small size online live broadcasting classes through the self-developed OMO system during the quarter.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Earnings
TAL Education cuts Q4 revenue view to $850.1M-$871.9M, consensus $996.92M » 17:02
02/28/20
02/28
17:02
02/28/20
17:02
TAL

TAL Education

$54.44 /

-0.58 (-1.05%)

The company previously…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Acasti receves Nasdaq notification over minimum bid requirements » 17:01
02/28/20
02/28
17:01
02/28/20
17:01
ACST

Acasti Pharma

$0.43 /

-0.0126 (-2.88%)

Acasti Pharma announced…

Acasti Pharma announced that on February 28, 2020, it received written notification from the Nasdaq Listing Qualifications Department for failing to maintain a minimum bid price of U.S.$1.00 per share for the last 30 consecutive business days, as required by Nasdaq Listing Rule 5550a2 - bid price. The Nasdaq notification has no immediate effect on the listing of Acasti Pharma's shares. Under Nasdaq Listing Rule 5810c3A - compliance period, Acasti Pharma has 180 calendar days, or until August 26, 2020, to regain compliance. If at any time over this period the bid price of Acasti Pharma's shares closes at $1.00 per share or more for a minimum of ten consecutive business days, Nasdaq will provide written confirmation of compliance and the matter will be closed.

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.