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BFRA

Biofrontera

$14.50

(0.00%)

07:35
04/16/19
04/16
07:35
04/16/19
07:35

Biofrontera reports secondary endpoint results from Phase 3 PDT study

Biofrontera reported results for the secondary endpoints of its Phase 3 clinical trial evaluating the safety and efficacy of conventional photodynamic therapy, or PDT, with Ameluz in combination with the BF-RhodoLED lamp for the treatment of actinic keratoses, or AK, on the extremities or trunk/neck. Patients were treated with Ameluz on one side of the body and with a placebo gel on the other side. In line with the result for the primary endpoint of the study, which showed a mean lesion clearance rate per patient's side of 86% for Ameluz compared to 33% for placebo, superiority of Ameluz was demonstrated for all secondary parameters investigated. Even if mild AKs were ignored and only moderate AKs were considered, mean lesion clearance rates per patient's side were 84% with Ameluz compared to 27% with placebo. In patients treated on the extremities, mean lesion clearance rates per patient's side were also 84% with Ameluz compared to 27% with placebo. Mean lesion clearance rates in the area trunk/neck were even higher. Furthermore, the comparison parameter "patient complete clearance" also emphasized the superiority of Ameluz: 67% of the patients' sides were completely cleared 12 weeks after the last PDT compared to 12% of the placebo-treated sides. All of the results were statistically highly significant. Thus, all secondary endpoints also confirm the superiority of Ameluz over the control group. These results support the primary endpoint data for the applications to the European Medicines Agency and FDA, which Biofrontera plans to submit during Q3.

  • 29

    Apr

BFRA Biofrontera
$14.50

(0.00%)

11/28/18
LSCM
11/28/18
INITIATION
Target $19
LSCM
Buy
Biofrontera assumed with a Buy at Lake Street
Lake Street analyst Thomas Flaten assumed coverage of Biofrontera with a Buy rating and $19 price target. All the pieces are coming together for Biofrontera and Ameluz, its photodynamic drug therapy for pre-cancerous and cancerous skin lesions, Flaten tells investors in a research note. He believes Ameluz's "superior" clinical profile will combine with a "compelling" reimbursement story in the U.S. and a "robust" clinical development strategy to drive sales growth.
12/28/18
LSCM
12/28/18
NO CHANGE
Target $19
LSCM
Buy
Lake Street does not see court ruling hurting Biofrontera's results
Lake Street analyst Thomas Flaten affirms a Buy rating on Biofrontera with a $19 price target after Dusa Pharmaceuticals announced Wednesday that the U.S. District Court for the District of Massachusetts issued a preliminary injunction prohibiting Biofrontera from using Dusa's trade secrets in its commercial activities. Dusa sells Levulan, which competes directly with Biofrontera's Ameluz in the United States, Flaten tells investors in a research note. The analyst does not anticipate the ruling will have any material negative impact on Biofrontera's ongoing business or financial results. However, Biofrontera and Dusa are engaged in multiple lawsuits which collectively create uncertainty around Biofrontera shares, adds Flaten.
01/03/19
BNCH
01/03/19
NO CHANGE
BNCH
Activision, Canopy Growth among Best Ideas for first half of 2019 at Benchmark
Benchmark analysts selected their Best Ideas for the first half of 2019, naming 16 stocks, including: Activision Blizzard (ATVI), BioTelemetry (BEAT), Biofrontera (BFRA), Ctrip (CTRP), Huazhu Group (HTHT), II-VI (IIVI), Intevac (IVAC), LHC Group (LHCG), Meredith (MDP), Marvell (MRVL), NeoGenomics (NEO), Pegasystems (PEGA), Silicon Labs (SLAB), Varonis (VRNS), Canopy Growth (CGC) and Waitr Holdings (WTRH).
03/26/19
BNCH
03/26/19
NO CHANGE
BNCH
Buy
Biofrontera's recent acne deals positive, says Benchmark
Benchmark analyst Bruce Jackson noted that Biofrontera announced an agreement to acquire U.S. dermatology company Cutanea Life Sciences following last week's announcement of a new collaborative research and development agreement with Maruho for Biofrontera's acne drug, Ameluz. He sees both deals as positive for both companies, noting that Biofrontera gains funding to move Ameluz forward more quickly and Maruho gains an expanded U.S. salesforce. Jackson keeps a Buy rating on Biofrontera shares.

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